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Wednesday, 09 November 2016 01:14

Tuberculosis and chronic kidney disease: an emerging global syndemic

By  Romanowski et al.
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The link between chronic kidney disease (CKD) and tuberculosis (TB) has been known for more than 40 years, but the interaction between these 2 diseases is still poorly understood. Dialysis and renal transplant patients appear to be at a higher risk of TB, in part related to immunosuppression along with socioeconomic, demographic, and comorbid factors. Meanwhile, TB screening and diagnostic test performance is suboptimal in the CKD population, and there is limited evidence to guide protocols. Given the increasing prevalence of CKD in TB endemic areas, a merging of CKD and TB epidemics could have significant public health implications, especially in low- to middle-income countries such as India and China, that are experiencing rapid increases in CKD prevalence and account for more than one-third of global TB prevalence. To begin addressing TB-CKD, a clear understanding of the relationship between these 2 conditions needs to be established, and consistent, evidence-based screening and treatment guidelines need to be developed.

This article was translated into Chinese, you can read it here

 Authors: Kamila Romanowski, Edward G. Clark, Adeera Levin, Victoria J. Cook, James C. Johnston

Reference: Kidney Int Volume 90, Issue 1, May 10 2016, Pages 34-40 ; doi:10.1016/j.kint.2016.01.034

Additional Info

  • Language: English
  • Contains Audio: No
  • Content Type: Articles
  • Source: KI
  • Year: 2016
  • Members Only: No
Read 3294 times Last modified on Wednesday, 09 November 2016 01:27