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Wednesday, 27 April 2016 14:09

Clinical Research: A prospective Study of clinico-epidemiology, outcome and catastrophic out-of-pocket Expenditure associated with obstetrical-AKI

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image iyerName: Raja Ramachandran

Hospital / Affiliation: Post Graduate Institute of Medical Education and Research, Chandigarh, India

Home Country: India

Host Country: India

Year: 2015

Status of your program: IN PROGRESS



Title of the project:

Aprospective Study of clinico-epidemiology, outcome and catastrophic out-of-pocket Expenditure associated with obstetrical-AKI


Acute Kidney Injury


Short description of the project or abstract:

Acute kidney injury (AKI) complicating pregnancy remains a cause of significant fetomaternal mortality and morbidity, particularly in developing countries. In addition to causing fetomaternal complications, it also results in significant health and financial adversary. The present study is a prospective study of pregnancy related dialysis dependent AKI. The objective of the study are to evaluate the causes and factors influencing outcome of obstetrical-AKI at a tertiary care referral hospital in India and to estimate the catastrophic out of pocket (OOP) expenditure associated with management of obstetrical-AKI on the family.
Eligible patients: All pregnant patients who will be admitted to our tertiary care referral hospital with AKI will be eligible for enrolment. AKI will be defined and staged according to Kidney Disease: Improving Global Outcomes (KDIGO) definition. Patients with pre-existing kidney disease with superimposed AKI will also be eligible for enrolment in this study.
Inclusion criteria: Pregnant/post-partum (till 2 weeks post delivery) patients with AKI as defined according to KDIGO definition at admission or during course in the hospital, willing to give informed consent.
Exclusion criteria: Failure to give informed consent by patient or legally acceptable representative and organ transplant recipients. Clinical features, laboratory investigation and the direct/indirect cost details at baseline (at the time of enrolment), discharge, and at monthly intervals for 3 months of onset of illness will be entered in an electronic database. After three months, patients will be followed by every 6 months with serum creatinine and urine routine examination only.


Learning or Research objectives:

Primary outcomes are clinical outcome at the end of 3 months and percentage of cases experiencing catastrophic OOP expenditure during the management of dialysis dependent AKI. Secondary outcomes are causes of obstetrical-AKI, direct and indirect expenses in the management of AKI and to create an electronic registery of Obstetrical-AKI.


Additional Info

  • Year: 2015
  • Status: In progress
  • Partners: ISN only
  • Region: Oceania and South East Asia
  • Country: India
  • Topics: AKI
Read 6618 times Last modified on Wednesday, 27 April 2016 14:43

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