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Wednesday, 04 May 2016 23:06

Clinical Research: Determinants of AKI among patients undergoing surgical interventions in a tertiary healthcare centre in Nigeria

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image YemiName: Yemi Raheem Raji

Hospital / Affiliation: University College Hospital, Ibadan/College of Medicine, University of Ibadan, Ibadan

Home Country: Nigeria

Host Country: Nigeria

Year: 2015

Status of your program: Ended

 

 

Title: 

Determinants of acute kidney injury among patients undergoing surgical interventions in a tertiary healthcare centre in Nigeria

Topic:

Acute Kidney Injury 

 

Short description of the project or abstract:

Acute kidney injury (AKI) is a major cause of morbidity and mortality among patients undergoing surgical interventions, it is an important contributor of prolong hospital stay and huge cost of treatments. It is a common occurrence in the developed countries particularly following cardiac surgeries. Though cardiac surgeries are not common in most sub-Saharan African countries, a lot of other major and minor surgeries are being performed on regular basis. The burden of AKI in these categories of patients have not being adequately described, perhaps occurrence of AKI may be responsible for the high perioperative mortality. Also, data on short and long term outcomes of AKI among patients undergoing surgical intervention in sub-Saharan Africa are limited. Since AKI is a preventable disease with enormous benefit of early intervention, identification of risk factor for AKI with appropriate intervention during the perioperative period have the potential of reducing the huge burden of AKI in this group of patients.

This study therefore aims to identify the perioperative risk factors and short term outcomes of AKI among patients undergoing surgery. This is a longitudinal short term follow up study of 373 consecutive and consenting adult patients undergoing surgical interventions at the University College Hospital, Ibadan, Nigeria. Relevant information will be obtained using standard case report forms and these information will include demographics, type and mode of surgeries, peri-operative risk factors for AKI and co-morbidities. Serial monitoring of the kidney function will be carried out weekly till discharge, using serum creatinine and urine output. The patient after discharge will be followed for 3 months, during this period systemic examination will be performed on all participants. Urinalysis and serum electrolytes, urea and creatinine will be carried out. Outcome measures will include development of acute kidney injury, need for renal replacement dialysis, cost and Length of hospital stay and death.

 

Learning or Research objectives:

Broad Objective: 

To identify determinants of perioperative Acute Kidney Injury among patients requiring surgical intervention at the University College Hospital.

Specific Objectives:

  • To determine the incidence rate of AKI among patients undergoing surgery in the perioperative period
  • To identify the risk factors for AKI among patients undergoing surgery in the perioperative period
  • To determine the impact of AKI on cost and length of hospital stay among patients undergoing surgery in the perioperative period
  • To determine the impact of AKI on renal replacement therapy and mortality rate among patients undergoing surgery in the perioperative period

 

Additional Info

  • Year: 2015
  • Status: In progress
  • Partners: ISN only
  • Region: Africa
  • Country: Nigeria
  • Topics: AKI
Read 6725 times Last modified on Wednesday, 27 February 2019 10:07

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