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Thursday, 05 May 2016 09:10

Clinical Research: Screening for Acute Kidney Injury among hospitalized children in Nigeria

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Debo Ademola
Adebowale D ADEMOLA

Hospital / Affiliation: Department of Paediatrics, University College Hospital, Ibadan / College of Medicine, University of Ibadan, Oyo State, Nigeria, West Africa

Home Country: Nigeria

Host Country: Nigeria

Year: 2016

Status of your program: In progress



Title of the project:

Screening for acute kidney injury among hospitalized children in Nigeria


Pediatric Nephrology 


Short description of the project or abstract:

There is limited prospective data on the incidence, aetiology and outcomes of acute kidney injury (AKI) in sub-Saharan. Data is crucial to developing strategies for prevention of AKI, to improve treatment and to measure the effect of interventions. We are therefore studying the incidence and outcomes of AKI in consecutive admissions to our paediatric emergency room.
The objectives of the study are as follows:

  • Determine the proportion of admitted children who develop AKI.
  • Describe the distribution of AKI by stage among affected patients.
  • Determine risk factors for AKI in terms of aetiology, age group, and nephrotoxin exposure.
  • Determine the short term outcomes (length of stay in hospital and death) in children with AKI.
  • Determine the proportion of patients with elevated blood pressure, proteinuria, reduced eGFR at 3 months follow up in patients who have suffered AKI.

To adapt the KDIGO AKI guideline and build a clinical pathway for prevention and management of AKI based on data generated in this study, prior Nigerian studies, local context and available resources.
We recruit consecutive patients aged > 28 days to 18 years admitted to our Paediatric Emergency Room whose parents consent. Patients who have received dialysis in the preceding 3 months or who have a functioning kidney transplant are excluded. At 25th April 2016, we have recruited about one hundred and eighty patients.


Additional Info

  • Year: 2016
  • Status: In progress
  • Partners: ISN only
  • Region: Africa
  • Country: Nigeria
  • Topics: Paediatric nephrology
Read 6806 times Last modified on Monday, 22 May 2017 11:25

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