Thursday, 06 February 2020 12:11

Milestones in Nephrology: Systemic autoimmune diseases and the kidney

Milestones in Nephrology Issue 2: Systemic autoimmune diseases and the kidney

To celebrate ISNs 60th anniversary, Kidney International’s “Milestones in Nephrology” series continues with a review of some of the original articles it has published on the effects of systemic autoimmune diseases on the kidney.

These articles have characterized the pathology and clinical course of these diseases and enabled the nephrology community to make informed decisions in treating these complex conditions:

  • The glomerular basement membrane as antigen: Goodpasture’s syndrome and anti-GBM glomerulonephritis (Wilson CB, Dixon FJ., 1973);
  • Severe GN but few glomerular antibodies: pauci-immune GN (Pusey CD, Rees AJ, Evans DJ, et al.);
  • Assessing the prognosis of lupus nephritis: the role of the kidney biopsy (Austin HA III, Muenz LR, Joyce KM, et al.); and
  • Personalizing immunosuppressive treatment in LN (Dooley MA, Hogan S, Jennette JC, et al.).

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