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World Kidney Day (WKD) organizers, ISN and IFKF, wish to thank all partners and collaborators who helped advance the WKD 2020 message highlighting the importance of preventive measures and the need for increased awareness in kidney disease prevention during this year’s event.

The 15th edition of WKD was marked worldwide on March 12 by stakeholders, regional and local authorities, the WHO, patients, and the general public, raising the profile of kidney diseases and generating solidarity among the nephrology community.

WKD reached 327 million people via social media: WKD content was liked, commented on, shared, and clicked 43 thousand times, and #worldkidneyday gained 154 million impressions.

The extent and variety of worldwide activities, which were adapted where necessary due to concerns surrounding the COVID-19 pandemic, are a testimony to the strength and engagement of the WKD community.

Inspiring campaign activities can be viewed, added to the WKD 2020 photo stream, or mapped here.

The Editorial Team of Kidney International would like to reassure our readership that we will continue to bring you high quality information throughout the COVID-19 pandemic to help all of us deal with the crisis and provide high quality care to our patients. We have a mechanism in place to rapidly review and arrive at publication decisions for papers on the kidney implications of COVID-19, and release these papers in an open access format within one week after acceptance. We believe the best way nephrologists can contribute to the fight against this disease is by arming ourselves with the best and most up-to-date data possible.

The Editors of Kidney International would also like to thank all of our Reviewers for their outstanding work in guiding the publication of high impact papers. We understand that for most of us now many of our academic activities have been curtailed as we focus our efforts on combating the virus. We apologize to our Authors for any delays encountered in the reviewing process for non-COVID-19-related articles. Normal turnaround time for Kidney International averages 14 days for all original manuscripts, and we will make every effort to maintain a short review process during this time of stress.

During the first quarter of 2020 the number of submitted manuscripts to Kidney International has increased by 15% and we are grateful to the authors for choosing to publish with us despite the pandemic. We are very much aware of the huge professional and personal difficulties Authors are facing, including the shut down of laboratories and the virtual stand-still of most clinical trials, and we will take these difficulties into account during the reviewing process.

Despite all of these challenges, The Editorial Team remains dedicated to the mission of Kidney International and we are proud to serve the kidney community and contribute, together with the International Society of Nephrology, to global kidney health. We are happy to hear from our readership and will appreciate any suggestions of how we can help you manage during this crisis.

To celebrate World Kidney Day (WKD), the ISN dressed the Manneken Pis fountain in Brussels in WKD colors to raise awareness of kidney health issues and activities.

The ISN team explained to onlookers the significance of the costume as it was unveiled, encouraging the public to use #worldkidneyday to accompany photographs taken of the WKD Mannekin Pis.

The ceremony was preceded by a meeting at Brussels City Hall alongside the Collège du Bourgmestre, the Echevin de la Ville de Bruxelles, the Echevin de la Culture, and representatives of the President of the Order of Friends of Manneken-Pis.

ISN Executive Director, Charu Malik, thanked city representatives for bringing the cause to the heart of Brussels and gave a short speech outlining the impact of kidney disease worldwide, calling for concrete measures in every country to promote and advance kidney disease prevention.

The Head of the Nephrology Department at the Cliniques Universitaires of Saint Luc and long-time ISN member, Professor Michal Jadoul, also addressed the audience to highlight simple preventative strategies available to healthcare professionals to identify kidney diseases in patients at an early stage.

ISN Kidney Health Professionals Working Group (KHP WG) members Rachel Walker and Paul Bennett submitted a paper that has been published as an editorial letter in the Renal Society of Australasia Journal 2020.

The KHP WG is a comprehensive and complementary nursing and allied health professional group formed by ISN in 2017 to address the gap in the non-nephrologist workforce and to encourage nursing involvement in program delivery and development.

The paper addresses the urgent need to develop nephrology nursing leadership within low- and middle-income countries to improve the management, safety, and quality of kidney care.

The development of a strong renal nursing and allied health workforce will increase the capacity to better meet the needs of people with kidney disease worldwide.

At a meeting held in December 2019 in Delhi, India, between the ISN President and Executive Director, and the Indian Society of Nephrology Governing Body, ISN and the Indian SN agreed to extend and formalize their existing partnership to include collaboration on all ISN programs and activities, demonstrating their mutual commitment to the advancement of nephrology in the South Asia region and globally.

This partnership seeks to advance regional capacity building through the ISN-Indian SN Fellowships, Sister Renal Centers (SRC), Educational Ambassadors (EAP), Continuing Medical Education meetings (CME), Scientific Writing Courses (SWC) and Interventional Nephrology Scholarships and a joint session at the ISN World Congress of Nephrology.

ISN President, Vivek Jha comments: ”This ongoing joint partnership continues to help reinforce the specialty of nephrology in the South Asia region and globally. It will help people become more aware of nephrology and kidney disease across the world, which is one of the missions of the ISN.”

In particular, this partnership is intended to encourage the training of South Asian and African Fellows in India, and Indian Fellows abroad, and to build partnerships between emerging and supporting Sister Renal Centers from the region. In both cases, the long-term objective is to create Regional Training Centers of excellence in India.

Indian Society of Nephrology President Prof. K.L. Gupta says: “We are committed to working for the advancement of nephrology in India, but also in low-and-middle-income countries from the South Asia Pacific region and around the world, and look forward to our continued collaboration with the ISN.”

As a result of this partnership, ISN and the Indian Society of Nephrology will co-jointly support the following Sister Renal Centers collaborations:

  • Pair between the Christian Institute of Health Sciences & Research in Dimapur, and the Christian Medical College in Vellore, both in India.
  • Pair between the University of Nigeria Teaching Hospital in Enugu, Nigeria and the George Institute for Global Health in Delhi, India.
  • Trio between the Hospital Central de Maputo, Mozambique, the Christian Medical College in Vellore, India and the University of California in Los Angeles, United States.

The next application deadline for the Fellowship Program is May 1. For the Sister Renal Centers Program, the deadline is October 1.

Monday, 16 March 2020 11:21

Attend the ISN 2020 Frontiers Meeting

The International Society of Nephrology, in collaboration with the Mario Negri Institute for Pharmacological Research, will hold the ISN 2020 Frontiers Meeting on ‘Complement-related kidney diseases: classification, genetics, and treatment’ from October 1-3, in Bergamo, Italy.

This specialist meeting will focus on the two prototypical complement-mediated kidney diseases: atypical hemolytic uremic syndrome (aHUS), and C3 Glomerulopathies/Membranoproliferative Glomerulonephritis (C3G/MPGN), giving scientists engaged in rare diseases the opportunity to speed up research and drug development in the field.

All ISN members are cordially invited to register to experience cutting-edge science presented by a global panel of clinical and scientific experts.

ISN encourages those directly involved in this area of expertise to reach a greater audience by submitting an abstract for the event.

High water intake and low urine osmolality are associated with favorable metabolic profile at a population level: low vasopressin secretion as a possible explanation” by ISN Hydration For Kidney Health (ISN-H4KH) Research Grant awardee, Sofia Enhörning, was published in the European Journal of Nutrition in February.

Sofia Enhörning et al, investigated if low total water intake or high u-Osm correlated with high fp-copeptin and components of the metabolic syndrome at the population level finding that low concentrations of the vasopressin marker copeptin were linked to high water intake, low u-Osm, and a favorable metabolic profile.

In 2015, Dr. Sofia Enhörning, from Skåne University Hospital in Malmö, Sweden, received an ISN Research Grant, with support from Danone Nutricia Research, for her project: "Plasma copeptin as a predictor of, and copeptin associated loci in, cardiorenal disease – population based prospective cohort studies and a mendelian randomization approach.” 

Prof. Philip KT Li
Prof. Philip KT Li

Honorary Professor of Medicine, Chinese University of Hong Kong and President of Hong Kong College of Physicians, and represents ISN on the WKD Joint Steering Committee 

Dr.Guillermo García García
Dr.Guillermo García García

Research Professor, University of Guadalajara Health Sciences Center, and Director of Nephrology, Hospital Civil de Guadalajara, Mexico, and represents IFKF on the WKD Joint Steering Committee

Preventive interventions – put in place in every country – could be the most suitable means of reducing the prevalence of chronic kidney disease (CKD) and the costs associated with it.


One in three people in the general population (an estimated 850 million people) is at increased risk of CKD. Worldwide, an estimated 10% of people have CKD, and estimates suggest nine in ten of those are unaware of their condition. The global burden of CKD is rapidly increasing with a projection of becoming the fifth most common cause of years of life lost globally by 2040.

Read the article

E-print version available here

Novel coronavirus disease (COVID-19) is a newly discovered contagious disease caused by SARS-CoV-2 virus, primarily manifesting as an acute respiratory illness with interstitial and alveolar pneumonia, but can affect multiple organs such as kidney, heart, digestive tract, blood and nervous system. The rapidly spreading outbreak which first emerged in Wuhan, Hubei Province in China in December 2019 has raised concerns about a global pandemic.

Read More

English Version Spanish Version

As part of the Saving Young Lives (SYL) project, 17 doctor-nurse pairs from eight countries across Africa received a week-long training in Acute Peritoneal Dialysis during the SYL Renal Skills Course at Red Cross Children’s Hospital in Cape Town, South Africa, from February 17 to 21, 2020.

The course directors, Red Cross’s Mignon McCulloch and Alp Numanoglu, conducted workshops on Pediatric Life Support Resuscitation, Vascular Access, PD for Nurses, and AKI.

The course included: a hands-on PD insertion workshop, and clinical stations in acute PD, automated PD, hemodialysis (HD), and Continuous Veno-Venous Hemofiltration (CVVH).

The 34 doctors and nurses in attendance left the course with increased capacity to provide acute PD services in adults and children with AKI in hospitals where access to treatment was not previously available.

Data collected by ISN from former SYL workshop participants indicates that over 500 patients with AKI have received treatment for acute PD through the SYL project and a 65% survival rate is reported.

After graduation, ISN Sister Renal Centers or ISN-TTS Sister Transplant Centers partnerships can opt to support a third emerging center within the region through the ISN SRC Trio Program.

Three recently graduated Trio partnerships demonstrate the valuable impact these collaborations can have on local nephrology capacity.

 

Emerging Institution: Nephrology Institute, Zhengzhou University, Zhengzhou (NIZU), China; Supporting Institution: Institute of Nephrology, Peking University, Beijing (INPU), China; Mentoring Institution: Renal Division, Brigham and Women’s Hospital (BWH), Harvard University.

Prior to 2014, the NIZU had a large number of patients with kidney disease but lacked diagnostic expertise and equipment in renal pathology. With the help of INPU and the BWH, they were able to set up their own pathology department for kidney diseases in Henan Province. Nurses and doctors received training in clinical and pathology skills to improve expertise and accuracy in the diagnosis and treatment of rare and complex diseases, and their prognosis.

The hospital wards grew from three to six, increasing bed capacity from 193 to 308. The renal replacement therapy center expanded to include two blood purification centers and two peritoneal dialysis centers. Equipment increased to include 132 blood dialysis machines, over 170 blood purification machines, and 45 continuous renal replacement therapy units. A peritoneal dialysis hotline was set up to provide better services for patients.

NIZU joined the TESTING and C-STRIDE clinical research trials initiated by INPU. 36 national projects were allocated to NIZU by various organizations including the Ministry of science and technology, the Medical Management Institute of National Health and Family Planning Commission, and the National Natural Science Foundation of China. 200 articles were published in Chinese medical journals.

In 2018, NIZU established the first Dialysis Pathway Operation Center for Uremia in the Henan Province. According to China Hospital Science and Technology Influence Ranking, the institute rose from 17th place in 2016 to 11th place in 2018.

 

Emerging Institution: Tikur Anbessa Specialized Hospital (TASH), Ethiopia; Supporting Institution: St. John’s Medical College, India; Mentoring Institution: Montreal Children's Hospital, Canada.

The goal here was to establish a pediatric nephrology service in Ethiopia, transfer knowledge and skills, and equip the emerging center in data collection and analysis to produce reliable, reputable studies.

The emerging center, initially run by only one senior pediatric nephrologist, expanded to acquire two additional pediatric nephrologists trained through the SRC Program. Two renal follow-up centers have now been set up, one in the emerging center and an additional institution in the capital as an outreach program. The supporting center provided acute PD and HD catheters, biopsy guns, and BP apparatus for all age groups. Children who have received transplants abroad can now receive post-operative care within the emerging center. The total number of pediatric nephrologists has increased to five in Ethiopia.

A pediatric nephrology subspecialty curriculum was developed for the emerging institution. Teaching materials were produced and Continual Medical Education (CME) meetings were held to reach pediatricians caring for children with kidney diseases.

With the support of the program, TASH made multiple poster presentations both nationally and internationally. In 2019, they received the best abstract award at the AFPNA congress in India for sharing their experience of using improvised acute PD solutions to provide RRT via rigid catheters. A research grant was awarded to TASH through the ISN Clinical Research Program to conduct the first large prospective AKI study in Ethiopia.

Bezaye Abebe, liaison officer at the emerging center, states: “The bright faces we see when our children beat death and come back for [a] follow-up, is a reason to push through every day against all the limitations in the country.”       

 

Emerging Institution: Susana López de Valencia, Colombia; Supporting Institution: Fundación Valle del Lili (FVL), Colombia Mentoring Institution: Boston Children’s Hospital.

The goal was to improve pediatric nephrology in the Southwest region of Colombia by:

  • creating an outpatient clinic Learning Center Program to support children with renal diseases,
  • training healthcare professionals in detection, prevention, and treatment innovations for renal diseases,
  • developing strategies to improve AKI treatment,
  • setting up an in-utero CAKUT database,
  • evaluating patients to detect early hypertension and proteinuria.

Through the program, staff from SLV were able to visit Boston Children’s Hospital to receive training. The emerging center benefitted from additional ISN programs, including fifteen Continuing Medical Education (CME) meetings hosting international speakers, and an Educational Ambassador (EA) Program visit from Dr Guido Filler, from the Children’s Hospital of Eastern Ontario, Canada.

Support from the urology and nephrology teams from Boston Children’s Hospital helped develop a myelodysplasia clinic as well as a pediatric nephrology unit in Popoyàn for the assistance and follow-up of pediatric patients with renal pathology. An approved AKI network was established in Cali and Popayàn Intensive Care Units.

Both the supporting and mentoring institutions provided training to two transplant surgeons, one adult nephrologist, one pediatric nephrologist, and one pediatric intensivist as well as three nurses enabling the development of a pediatric renal transplant service at Hospital San Jose-Popayàn including a transition program for adolescents with kidney transplants.

Several research studies were carried out and a research group on kidney diseases in the indigenous population was initiated as part of an effort to increase awareness and associated risks of renal diseases in children in the TOTORO aboriginal community.

In a final report on the impact of the program, the emerging center stated: “We have always received permanent and timely support for everything requested from the ISN…We believe that ISN is an example of excellent support for the entire nephrology community that encourages people to work in an organized way, impacting the prevention of kidney disease in the world.”

Celebrating ISN’s 60th anniversary, Kidney International’sMilestones in Nephrology” series continues with a review of some of the original articles it has published on the treatment of glomerular disease, publications that helped make significant changes in patient management:

  • Shorter term corticosteroids are equally effective as longer term in primary nephrotic syndrome in children (Yoshikawa N, Nakanishi K, Sako M, et al.)
  • Calcineurin inhibitors in focal segmental glomerulosclerosis and membranous nephropathy (Cattran DC, Appel GB, Hebert LA, et al.)
  • High-dose melphalan and autologous stem cell transplantation is feasible in end-stage kidney failure patients with amyloid light-chain (AL) amyloidosis (Casserly LF, Fadia A, Sanchorawala V, et al.)
  • Renal effects of enzyme replacement therapy in Fabry disease (FD) (Thurberg BL, Rennke H, Colvin RB, et al.)

Read more

The ISN is pleased to announce this year’s recipient of the Schrier Award, which recognizes the most deserving partnership from recently graduated ISN Sister Renal Centers (SRC) Program and ISN-TTS Sister Transplant Centers Program pairs.

The ISN Sister Renal Centers Program chair and deputy chair, the ISN-TTS Sister Transplant Centers Program co-chairs, and the ISN Programs chair reviewed the applications of six SRC pairs and three trio partnerships. All nine collaborations earned significant merit but the jury recognized notable excellence from the SRC Tanzania-Canada partnership between the Kilimanjaro Christian Medical Centre (KCMC) in Tanzania and the Queen’s University in Canada. This pair availed of additional ISN Programs to build a strong and durable partnership, achieving successful and sustainable outcomes.

The SRC Program played a crucial role in developing a number of programs at KCMC that aimed to build sustainable and high-quality diagnostic and treatment facilities for kidney diseases, as well as set up research projects in line with local priorities:

  • The Program funded Dr. Kilonzo to complete a two-year ISN Fellowship at the University of Cape Town under the mentorship of Prof. Bryan Rainer. The training, and the additional mentorship provided by Dr. Yeates from the supporting center, equipped Dr. Kilonzo to help set up acute PD and Clinic Care programs at KCMC. The initiative included outpatient nephrology clinics built for the follow-up of patients and eventually became part of the Saving Young Lives Project. Trainees Dr. Suda Ghosh and Dr. Huda Akrabi received ISN Fellowship funding in subsequent years further contributing to the strength of the center.
  • A hemodialysis program was launched that has expanded from an initial 7 chairs to 40 chairs in 2020 and is now active 24 hours a day, seven days per week.
  • Dr. Kilonzo and Dr. Yeates, alongside other young nephrologists, founded the Nephrology Society of Tanzania (NESOT), which meets annually for a scientific conference. The strong network created through the Society has increased lobbying power to petition local government to provide ongoing resources, actively promoting the need for improved kidney health in Tanzania.
  • An annual continuing education program for nephrology nurses was developed: Ms. Emy Cowlan, an experienced hemodialysis nurse trainer from Ontario, visited KCMC twice during the program providing mentorship to nurses and organizing an off-site educational meeting.
  • An ISN Clinical Research grant was awarded to KCMC in 2018 to support an ongoing research study, supervised by Dr. Yeates, to identify risk factors and outcomes of community-acquired AKI in adults and children.
  • KCMC will shortly begin a Sister Transplant Centers partnership with Manchester University in the United Kingdom aiming to build capacity for living donor transplants at KCMC over the coming years.

Having graduated, KCMC is now planning to form a trio to support a new emerging center in Northern Tanzania. Dr. Karen Yeates comments “We honestly feel that the SRC funding has had a real and measurable impact on lives saved in Tanzania through the successive and systematic building of the nephrology program though the SRC partnership.”

The deadline for the next round of Fellowship applications is May 1, 2020.

The ISN Fellowship Program offers nephrology training to physicians from low-resource countries and provides a valuable opportunity to grow professionally and to improve kidney healthcare in emerging countries by becoming established leaders in the field. A recent article outlines the significant results that are attainable through the program.

Read the guidelines and apply here.

To facilitate hands-on training experiences and benefit from similar cultural and linguistic environments, the ISN will prioritize candidates applying to train in a Host Center from their home region.

All Fellowship applicants must establish a training plan in collaboration with the Host Mentor reflecting the skills and knowledge required by their Home Institution to be implemented at their home clinic.

Candidates who wish to train in all aspects of nephrology or apply for long-term training (six months or more) have a greater chance of success if hands-on training is secured. If candidates are unable to obtain hands-on experience, they are advised to apply with a well-designed, short-term (up to 6 months) training program enabling them to achieve specific goals in an observer role.

For any enquiries concerning your application please contact fellowship@theisn.org.

Tuesday, 03 March 2020 14:36

Three Days Until World Kidney Day

 

The fifteenth edition of World Kidney Day takes place on Thursday, March 12, 2020.

 This global campaign highlights the importance of kidneys to overall health and raises awareness of risk factors to reduce the frequency and impact of kidney disease and its associated health problems.

The 2020 campaign focuses on preventive interventions to avoid the onset and progression of kidney disease calling for “kidney health for everyone everywhere – from prevention to detection and equitable access to care.”

 Early prevention and delay of progression of kidney diseases through educational campaigns, patient empowerment, cross-disciplinary training for medical personnel, and integrated programs for non-communicable diseases are sustainable options to reduce the cost and consequences of these conditions for both individuals and countries.

 The World Kidney Day Campaign owes its success to the enthusiasm and dedication of members of the public, doctors, politicians, and celebrities. This support is essential to the campaign’s ultimate goal: preventing kidney diseases and improving the lives of those living with kidney diseases.

Celebrate on March 12 by promoting a positive message of prevention through a healthy lifestyle. And support people living with or recovering from kidney disease by sharing online using the hashtag #WorldKidneyDay.

SUPPORT A NEW FELLOWSHIP

The ISN is pleased to announce a new Fellowship in honor of Dr. Ravindra Mehta, the Ravi Mehta AKI Fellowship.

The fund has been set up in collaboration with Ravi Mehta’s friends and colleagues in recognition of his leadership and to honor his contribution to global health and education.

The ISN invites you to make a financial contribution to the Ravi Mehta AKI Fellowship to:

  • Support a Fellow: One ISN Fellow per year from a low-resource country will be able to train in Acute Kidney Injury;
  • Make a difference: Successful Fellows will be in a position to improve the standard of care in their home country after a period of training at an ISN-approved institution of their choice.

 

Dr. Mehta has dedicated his professional and personal life to reducing the burden of kidney disease across the world through research, training, education, collaboration, and global advocacy.

MAKE A DONATION TO THE RAVI MEHTA AKI FELLOWSHIP FUND

MAKE A DONATION TO THE RAVI MEHTA AKI FELLOWSHIP FUND

 

To donate using a check drawn on a US Bank, please send to the address below
with the reference “Ravi Mehta AKI Fellowship”:
International Society of Nephrology
340 North Ave, 3rd Floor
Cranford, NJ 07016
USA

U.S. donors can claim a tax deduction for charitable giving. The ISN Tax Identification Number is 59-1776707.

Monday, 24 February 2020 10:42

ISN Impact: Sister Renal Centers Program

In the early nineties, ISN leadership began discussions on active collaboration between established kidney care centers and emerging centers from low-resources areas. By 1996, 17 active partnerships were established and a further 16 were in a formative stage. These paired centers would become known as the Sister Renal Centers . Today, 63 partnerships are active within the Sister Renal Centers Program.

The overall impact of the ISN SRC Program on emerging centers is highlighted here by describing the successes of three SRC partnerships who graduated in 2019, having completed the six-year process involving a gradual progression through three possible upgrades from level C to level A.

Emerging Institution: Colonial War Memorial Hospital, Fiji; Supporting Institution: Concord Repatriation General Hospital, Australia.

When the partnership was formed in 2014, the goal was to establish the first Nephrology service in Fiji, acting as a hub for the development of Nephrology in the Pacific Islands.

Supported by the program, the hospital published a paper demonstrating that Fiji has one of the highest rates of end-stage kidney disease worldwide. The conclusions of this analysis were pivotal in the Fijian government’s decision to provide funding to set up a National Kidney Research and treatment center to improve access to kidney care for all.

The SRC program has been directly responsible for establishing organized renal care in Fiji. The Colonial War Museum hospital now has a dedicated renal clinic team and has established and maintained a renal biopsy program as well as a hemodialysis for acute kidney injury program that has treated hundreds of patients. The Fiji Nephrology Symposium has been run annually for five years and is now aligned with the Fiji Medical Association conference.

An electronic dialysis registry has been established to support improved data collection on the characteristics and outcomes of chronic dialysis in Fiji. A nascent culture of research has emerged with one peer-reviewed publication and seven abstracts accepted and presented, ensuring an improved scorecard on the Global Kidney Health Atlas between 2017 and 2019.

Fiji now has a Nephrology workforce comprising one nephrologist, one ISN Fellow, general physicians supporting Nephrology, and a network of motivated and increasingly experienced renal nurses able to benefit the next generation of clinicians.

Emerging Institution: National Medical Research Center for Children´s Health, Institute of Pediatrics NCZD Moscow, Russia; Supporting Institution: Department of Pediatric Nephrology and Transplantation, New Children´s Hospital, University of Helsinki, Finland.

National center kidney health moscow

The main goal was to begin pediatric renal r-transplantations (KT) in the emerging center in Moscow. The first KT was performed on November 1, 2017. Since then, 25 KT’s have been performed with great success at the emerging center.

Nephrologists, surgeons, and anesthesiologists were trained in intensive care, fluid and electrolyte management, surgical techniques, induction, and continuous immunosuppression at the supporting center in Helsinki in 2018 and 2019. Supporting center personnel visited Moscow twice with educational programs and activities addressing CKD care and the complications of pediatric kidney transplantation.

Secondary goals were also attained: general principles and approach in psychosocial issues of pediatric CKD and transplantation were shared between specialists at the centers. The clinical practice of congenital nephrotic syndrome was explored and conveyed to the emerging center. Indications and principles of molecular genetics in pediatric kidney diseases were discussed at length and a program of care for children with hereditary kidney disease was developed collaboratively and implemented at the emerging center.

The success of the program secured the employment of two experienced doctors at the center.

Emerging Institution: Viet Duc Hospital, Vietnam; Supporting Institution: Juntendo University, Japan.

juntendo university japan

The focus was on improving the knowledge of local nephrologists in renal care and training local pathologists.

From 2014 to 2019, six Continuing Medical Education (CME) courses in Renal Pathology were held from basic to advanced levels. Further courses took place in nephrology, dialysis, and transplantation covering all aspects of kidney diseases.

Staff from the Pathology and Kidney Diseases and Dialysis departments of the Viet Duc Hospital attended short-term training courses in Japan, and the Japanese Society of Nephrology (JSN) and the Asian Pacific Society of Nephrology (APSN) held scientific meetings in Tokyo.

Prior to the SRC Program, only two basic staining techniques were available for kidney biopsy samples for optic microscopy. Now five basic staining techniques are carried out routinely. The number of kidney biopsies carried out per year has increased from 50 cases in 2014 to 300 cases in 2019.

In order to promote the early detection and prevention of kidney disease and provide more evidence for policy making within the Vietnamese health care system, an epidemiology survey and urinalysis were conducted in 2695 Vietnamese subjects to detect risk factors for CKD and urine abnormalities.

The Viet Duc Pathology department has become a center of reference for seven other hospitals. Collaborative relationships between nephrologists and other relevant specialists in Hanoi and Northern Vietnam have been established as well as between local and international specialists creating the potential for future research projects and motivating young professionals to work in the field.

Moi Teaching and Referral Hospital

Emerging Institution: Moi Teaching and Referral Hospital (MTRH), Kenya Supporting Institution: Amsterdam UMC (VUme), The Netherlands

Building on an existing partnership between the Vrije Universiteit medical center in Amsterdam and the Moi Teaching and Referral Hospital in Kenya, the ISN Sister Renal Centers Program supported the development of a renal unit, including dialysis and renal transplantation, at MTRH.

Vascular surgeons from VUme visited MTRH to teach local surgeons how to create an AV fistula. The unit was eventually able to establish a training program for dialysis nurses and now performs over 1600 dialysis treatments per month.

Training was given to all nephrologists, surgeons, and operating room nurses by their VUme counterparts so that renal transplants could be performed at MTRH. The first three living-related renal transplant procedures were successfully performed by collaborating physicians from VUme and MTRH, and repeated several times a year until 2018 when MTRH carried out their first fully independent transplant procedure. In 2019, 43 living-related renal transplant procedures were performed and at least one procedure every other week is scheduled in 2020.

The ISN congratulates 11 new Fellows approved by the ISN Fellowship Committee following the first round of applications for 2020.

This year, Priyanka Subramani, from the Central and Northern Adelaide Renal and Transplantation Service in Australia, will undertake an ISN Reverse Fellowship at the Mbeya Zonal Referral Hospital in Tanzania under the supervision of Dr. Francis F. Fredrick. The ISN Reverse Fellowship is for young nephrologists from well-resourced settings willing to spend up to 12 months in a low or middle-income country (LMIC) to train clinical staff onsite through direct mentorship.

Etienne Ntabanganyimana, from the Gihundwe Hospital in Rwanda, was selected as the first Detlef Schlöndorff Fellow. He will travel to India to spend 12 months training in interventional nephrology under the mentorship of Prof. Santosh Varughese at the Christian Medical College in Vellore, India.

Na Tian from the General Hospital of Ningxia Medical University in China was awarded the ACN-ISN-HKSN Scholarship. This initiative supports young nephrologists living and working in China who are looking for short-term training in either their home country or Hong Kong and is co-funded, with the ISN, by the International Association of Chinese Nephrologists (IACN) and the Hong Kong Society of Nephrology (HKSN). Na Tian will train in the management of peritoneal dialysis for three months under the supervision of Prof. Philip K.T. Li at the Prince of Wales Hospital in Hong Kong.

A full list of finalists and their host institutions can be viewed below.

ISN thanks the following sponsors for their involvement in this project: The British Renal Association; the Detlef Schlöndorff Fund; Elsevier; the Hong Kong Society of Nephrology (HKSN); the International Association of Chinese Nephrologists (IACN); Kidneys for Life; Kidney Research UK; the Schrier Fund.

The next deadline for Fellowship applications is May 1, 2020. Read the guidelines here.

As part of its vision to ensure equitable access to kidney health globally, the International Society of Nephrology (ISN) is proud to launch the Emerging Leaders Program (ELP). With the aim of building a global talent pool of future leaders, the ELP welcomes ISN members interested in shaping the direction of kidney health through professional development and improved understanding of health policy and implementation to ensure health promotion and access to prevention, control and management of kidney diseases.

The Program will provide participants worldwide with the opportunity to work closely with international experts in order to develop leadership and advanced capabilities in:

  • implementation science and research;
  • developing and implementing evidence-informed policy;
  • evaluation, development and management of health systems;
  • principles of entrepreneurship, advocacy and communications;
  • influencing stakeholders including policymakers, funders, implementers and media.

To participants, the ELP offers (1) becoming part of a global network consisting of experts who positively impact the kidney health agenda around the world through collaboration as well as high quality and multidisciplinary research in discovery and implementation science; (2) empowerment to find innovative ways to let their voices be heard so they can act as agents of change at the local and international level and (3) access to continuous professional development to acquire the necessary resources, skills and knowledge to take on leadership roles locally and globally

Successful candidates will be matched with a mentor drawn from the ISN leadership to help them map out their journey and reach their career goals.

Eligibility Criteria

  • Early career academic (MD and/or PhD) as defined by being at the Fellow/Instructor/Assistant Professor level or equivalent for other countries.
  • The call is open to non-academics at comparable career levels who are interested in improving the global kidney health agenda.
  • Talented and motivated early-career professional (less than 10 years out of residency or training)
  • Ability to demonstrate commitment to the improvement of global kidney health using a collaborative approach.
  • Be a member of ISN (Not a member? Join here)

 

Applications

The application session will open shortly after the Congress. ISN leaders and staff will be available at the ISN booth at the World Congress of Nephrology in Abu Dhabi (26-29 March 2020) to answer questions from and guide those interested in applying.

If you have questions at this time, please contact Marie-Pierre Smal at mpsmal@theisn.org

ISN’s two Sister Centers Programs (SRC and ISN-TTS STC) link emerging renal and transplant centers with centers of excellence for long-term partnerships. The educational guidance provided by the supporting center over a six-year period aims to help the emerging center become self-sufficient and offer improved patient care.

In 2020, 13 new pairs (listed below) were approved by the ISN Sister Centers Program Committees to start a collaborative process, increasing the total number of centers that are currently active within the program to 63.

ISN is increasingly encouraging partnerships created within the same region where there is a shared understanding of language, culture, and any resource-related constraints; such regional collaborations are also more cost-effective for all partners. Graduating pairs are also encouraged to consider collaborating with a third center from the region to further enhance capacity in the locality.

Thanks to ISN’s alliance with The Transplantation Society, there is increasing support for centers willing to develop transplantation services.

The next round of applications for these programs closes on October 1. In order for applications to receive careful consideration, it is recommended that complete applications be submitted well in advance of the deadline date. Apply here:

ISN Sister Renal Centers Program: http://src.theisn.org

ISN-TTS Sister Transplant Centers Program: http://stc.theisn.org

 

13 new 2020 partnerships:

  • SRC Albania-Germany
  • SRC Argentina-Argentina
  • SRC India-India1
  • SRC India-UK5
  • SRC Nigeria-Nigeria-USA4
  • SRC Samoa-New Zealand
  • SRC Sri Lanka-UK2
  • SRC Uganda-USA
  • SRC Uzbekistan-Russia-Finland
  • SRC Vietnam-UK5
  • ISN-TTS STC Argentina-USA
  • ISN-TTS STC India-UK1
  • ISN-TTS STC Sri Lanka-Spain

The ISN Advancing Clinical Trials Toolkit is designed to assist in carrying out meaningful and robust clinical trials, or to become involved as a trial site, with the primary intention of improving patient care.

Available online for the first time at the ISN World Congress of Nephrology (WCN), Congress delegates are invited to experience the toolkit at the ISN booth. The online link to the ACT toolkit will be shared through the ISN Insight once it goes live.

The ISN-ACT Committee has drawn on the contributions of experts from around the world to help clinicians and researchers at all stages of a trial, including:

  • protocol development
  • funding requirements
  • registration
  • sourcing the investigational medicinal product
  • contractual agreements
  • ethical/regulatory approvals
  • training study staff
  • preparing for data collection
  • analysis of results
  • publication and dissemination
  • potential use in disease control

This initiative aims to encourage an increase in the number of international, high-quality clinical trials in nephrology to help identify the optimal prevention and treatment of kidney disease.

Kidney International Supplements (KIS) has published a set of papers describing the background, rationale, and action plans for developing a strategic approach to increase access to integrated end-stage kidney disease (ESKD) care worldwide over the next decade. Read this special edition here.

Following March 2018's second Global Kidney Health Summit organised by the International Society of Nephrology (ISN), the primary paper of the Summit, 'Increasing access to integrated ESKD care as part of Universal Health Coverage,’ was published in April 2019. Additional outputs from the diverse globally-representative multidisciplinary group of authors are now being published in KIS.

A range of issues relevant to the care of patients with ESKD, especially in the resource limited settings of low and lower-middle-income countries, have been discussed in the papers. They include global differences in the incidence and prevalence of ESKD and modality of care; ethical principles and advocacy for integrated care; sustainable dialytic care; safety and quality standards; and kidney transplantation and supportive care as components of integrated care. Two additional papers discuss findings of a survey that gathered global data on dialysis funding, eligibility, procurement, and monitoring, and assembled 88 clinical protocols, and present a series of 15 country case studies documenting context-driven variability in approaches to kidney care while demonstrating the potential advantages of multi-stakeholder engagement.

Each article includes perspectives from around the globe, represents the current state of knowledge, critically evaluates gaps and offers concrete suggestions to address those gaps. 

The Lilian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease (PKD) will now be awarded annually. ISN is grateful to Thomas Kaplan and the Recanati-Kaplan Foundation for their generosity in making this possible.

The Lillian Jean Kaplan Prize recognizes individuals exhibiting excellence and leadership in PKD clinical or basic research that improves knowledge and treatment of PKD. It is a prestigious award in this field.

This year’s award will be presented in a one-hour session taking place on Sunday, March 29 from 12 p.m. to 1 p.m. in Capital Suite 7 of the Abu Dhabi National Exhibition Center (ADNEC).

Andy Betts, CEO of the PKD Foundation, and Dr. Nathan Levin, Chair of the Lillian Jean Kaplan Prize Advisory Committee, will introduce and present this year’s award. The winner will deliver a scientific lecture.

Learn more

Monday, 24 February 2020 09:32

Mannekin Pis dresses up for World Kidney Day

All are warmly invited to join ISN at the Mannekin Pis, a public fountain statue and well-loved icon in the heart of Brussels, at 1 p.m. on Thursday, March 12, 2020, as part of ISN’s WKD campaign.

Mannekin Pis will dress up in World Kidney Day colors to grab the attention of passers-by at this prime location near the Grand Place on rue de l’Etuve.

Members of the ISN team will be present at the landmark all afternoon to promote a positive message of kidney health and hand out information about kidney disease prevention, drawing public attention to those living with or recovering from kidney disease.

Click here for addintional information

Monday, 10 February 2020 11:19

ISN Attends WHO Executive Board Meeting

ISN was invited and pleased to attend the 146th Session of the Executive Board (EB) of the World Health Organization (WHO) from February 3-8, 2020.

This year the EB Meeting addressed topics extremely relevant to kidney patients, such as the advancement of primary care and the implementation of the recent Political Declaration on Universal Health Coverage and noncommunicable diseases (NCDs).

In this context, ISN called on the WHO and Member States to recognize the immense burden of kidney disease worldwide and asked for urgent measures to ensure that kidney health is fully integrated in national NCD plans.

Concerning the EB meeting, Charu Malik, ISN Executive Director, commented: “ISN is proud to represent the kidney health community. We call for an integrated approach to kidney care that is people-centered and leaves no one behind. Action is needed now for the 850 million people affected by kidney disease globally!

Read the oral statements ISN made at the EB meeting here:

Statement on Item 146.6

Statement on Item 146.5

Statement on Item 146.22.3

Statement on item 146.7.2

Since 1985, the ISN Fellowship Program has supported over 800 fellows from 90 emerging countries. The program encourages professional fulfillment and supports equitable healthcare by establishing Fellows as valuable leaders in their home region qualified to share knowledge and experience.

Many past ISN Fellows make use of other ISN Programs and become involved in ISN committees or supporting groups. To highlight the potential for personal growth and professional influence that the Fellowship Program provides to all Fellows, ISN presents here a sample of past Fellows with notable active participation in and commitment to ISN activities.

 

The ISN Fellowship Program: Abduzhappar Gaipov, from Kazakhstan

An ISN member since 2012, Abduzhappar Gaipov, from Kazakhstan, became an ISN Investigator in 2014 getting involved in the AKI Global Snapshot study. He completed an online certified course on Renal Pathology (ISN-ANIO CNC Program) in 2016 at which time he joined the Young Nephrologists Committee and began serving on the ISN NIS & Russia Regional Board.

Dr. Gaipov was awarded a Fellowship in 2017, training in clinical and epidemiological research methodology under mentorship from Prof. Csaba P. Kovesdy at the University of Tennessee Health Science Center in the USA.

In 2017, he organized the CME meeting: “1st National Congress of Kazakhstan Society of Nephrologists, Dialysis and Transplant” in Aktau, Kazakhstan and joined the ISN-ACT (Advancing Clinical Trials) initiative.

He now serves on the CME Committee and is a member of the ISN Council, as Deputy Chair of the ISN NIS & Russia Regional Board.

 

The ISN Fellowship Program: Anthony Russell Villanueva, from the Philippines

Anthony Russell Villanueva, from the Philippines, was awarded a Fellowship in 2012 and received clinical training in general nephrology and research in renal medicine at the University of Michigan in the USA under Dr. Panduranga Rao at the University of Michigan in the USA from 2013-2014.

In 2018, Dr. Villanueva became Liaison Officer at the Emerging Center, the National Kidney and Transplant Institute in Quezon City, Philippines, for the ISN .

In 2019, he began serving on the ISN Oceania and South-East Asia Regional Board; and in the ISN Renal Disaster Preparedness Working Group, which was set up to provide expertise and assistance in renal-related matters in emergency situations.

Facilitated by his involvement with the ISN, Dr. Villaneuva took over as training officer at one of the largest Nephrology Training Programs in the Philippines and helped set up a Glomerulonephrotis Clinic. Currently an assistant program manager of the Renal Disease Control Program (REDCOP), he is able to promote preventative nephrology to local government units.

 

The ISN Fellowship Program: Fatiu Abiola Arogundade, from Nigeria

Fatiu Abiola Arogundade, from Nigeria, Africa, became an ISN member in 1999. In 2001, he undertook a Fellowship at the Cairo Kidney Center in Egypt, training for one year.

He has been a member of various ISN Committees over the years, including the Sister Renal Centre Committee and the Committee on Kidney Health in Disadvantaged Populations.

Dr. Abiola coordinated the SRC relationship between Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, and the Division of Nephrology at the University of Virginia which graduated from Category A in 2018. He was Home mentor to four ISN Fellows between 2012-2019 and an EAP program organizer in 2013. He has frequently been an abstract reviewer at the WCN having published 84 papers in peer-reviewed national and international journals himself.

Fatiu Abiola is currently a member of the Educational Ambassadors Committee.

 

The ISN Fellowship Program: Dr. Rolando Claure-Del Granado, from the University of San Simón in Cochabamba, Bolivia,

Dr. Rolando Claure-Del Granado, from the University of San Simón in Cochabamba, Bolivia, was awarded an ISN Fellowship in 2009 to undertake a one-year research Fellowship under mentorship from Dr. Ravindra L. Mehta in the Division of Nephrology at the University of San Diego, USA. The goal was to obtain further exposure to clinical research in acute renal failure and continuous renal replacement therapies. His training combined practical experience in a clinical research project with a core curriculum in clinical research methodology.

In 2015, Dr. Claure-Del Granado organized a CME meeting, ‘YNC 0by25 Workshop’ on AKI, in Santa Cruz de la Sierra, Bolivia, in collaboration with the Bolivian Society of Nephrology. In 2019, he arranged the 12th International Bolivian Congress of Nephrology. This meeting provided a comprehensive review of advances in clinical care and research in AKI, CKD, and Kidney Transplant and featured three workshops including a hands-on workshop on Hemodiafiltration.

Dr. Claure-Del Granado was chair of the Young Nephrologists Committee from 2016-2018. He is now a member of the Fellowship Committee and the Emerging Center Leader for the current SRC partnership between Hospital Obrero #2, C.N.S./Universidad Mayor de San Simon in Bolivia and the University of California San Diego. I think he is also very active on social media – ask fer; should mention that; and he is still a member of YNC – confirm with Miguel

 

The ISN Fellowship Program: Dr. Mirna Aleckovic-Halilovic, from the Clinic of Internal diseases at the University Clinical Center Tuzla in Bosnia and Herzegovina

Dr. Mirna Aleckovic-Halilovic, from the Clinic of Internal diseases at the University Clinical Center Tuzla in Bosnia and Herzegovina, trained for six months under Dr. Ahmed Aimun at the Royal Preston Hospital in the UK in 2015. An SRC pairing was also established between these institutions. Dr. Aleckovic-Halilovic acknowledged the advantage of being able to participate in both these programs simultaneously, stating that they “benefit each other in so many ways and facilitate achieving [the] purposes of both.”

Dr. Aleckovic-Halilovic was able to improve transplantation medicine in both her home institution and in her home country as a whole by adopting a higher quantity of biopsies using new biopsy techniques. She shared her expertise through research and publications and assisted colleagues from Bosnia and Herzegovina and Croatia in their applications for ISN Fellowships.

Dr. Aleckovic-Halilovic joined the Young Nephrologists Committee and became a member of the Eastern and Central Europe Regional Board in 2017 and a member of the ISN Clinical Research Committee in 2019.

Last year, she organized a week-long Educational Ambassador visit by Dr. Ahmed Aimun on Glomerular Diseases with a focus on hands-on training in Kidney Biopsy.

 

Apply for an ISN Fellowship here.

Since 1985, the ISN Fellowship Program has supported over 800 fellows from 90 emerging countries. The program encourages professional fulfillment and supports equitable healthcare by establishing Fellows as valuable leaders in their home region qualified to share knowledge and experience.

Many past ISN Fellows make use of other ISN Programs and become involved in ISN committees or supporting groups. To highlight the potential for personal growth and professional influence that the Fellowship Program provides to all Fellows, ISN presents here a sample of past Fellows with notable active participation in and commitment to ISN activities.

An ISN member since 2012, Abduzhappar Gaipov, from Kazakhstan, became an ISN Investigator in 2014 getting involved in the AKI Global Snapshot study. He completed an online certified course on Renal Pathology (ISN-ANIO CNC Program) in 2016 at which time he joined the Young Nephrologists Committee.

Dr. Gaipov was awarded a Fellowship in 2017, training in clinical and epidemiological research methodology under mentorship from Prof. Csaba P. Kovesdy at the University of Tennessee Health Science Center in the USA.

In 2017, he organized the CME meeting: “1st National Congress of Kazakhstan Society of Nephrologists, Dialysis and Transplant” in Aktau, Kazakhstan and joined the ISN-ACT (Advancing Clinical Trials) initiative.

He now serves on the CME Committee and is a member of the ISN Council, as Deputy Chair of the ISN NIS & Russia Regional Board.


Anthony Russell Villanueva, far right.

Anthony Russell Villanueva, from the Philippines, was awarded a Fellowship in 2012 and received clinical training in general nephrology and research in renal medicine at the University of Michigan in the USA under Dr. Panduranga Rao at the University of Michigan in the USA from 2013-2014.

In 2018, Dr. Villanueva became a key participant in the ISN Sister Renal Centers (SRC) partnership co-sponsored by ISN and the Asian Pacific Society of Nephrology. He took on the role of Liaison Officer for the Emerging Center at the National Kidney and Transplant Institute in Quezon City in the Philippines who were supported through the program by Tan Tock Seng Hospital in Singapore.

In 2019, he began serving on the ISN Oceania and South-East Asia Regional Board; and in the ISN Renal Disaster Preparedness Working Group, which was set up to provide expertise and assistance in renal-related matters in emergency situations.

Facilitated by his involvement with the ISN, Dr. Villaneuva took over as training officer at one of the largest Nephrology Training Programs in the Philippines and helped set up a Glomerulonephrotis Clinic. Currently an assistant program manager of the Renal Disease Control Program (REDCOP), he is able to promote preventative nephrology to local government units.

Fatiu Abiola Arogundade, from Nigeria, Africa, became an ISN member in 1999. In 2001, he undertook a Fellowship at the Cairo Kidney Center in Egypt, training for one year.

He has been a member of various ISN Committees over the years, including the Sister Renal Centre Committee and the Committee on Kidney Health in Disadvantaged Populations.

Dr. Abiola coordinated the SRC relationship between Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, and the Division of Nephrology at the University of Virginia which graduated from Category A in 2018. He was Home Mentor to four ISN Fellows between 2012-2019 and an EAP program organizer in 2013. He has frequently been an abstract reviewer at the World Congress of Nephrology (WCN) having published 84 papers in peer-reviewed national and international journals himself.

Fatiu Abiola is currently a member of the Educational Ambassadors Committee.

Rolando Claure-Del Granado, from the University of San Simón in Cochabamba, Bolivia, was awarded an ISN Fellowship in 2009 to undertake a one-year research Fellowship under mentorship from Dr. Ravindra L. Mehta in the Division of Nephrology at the University of San Diego, USA. The goal was to obtain further exposure to clinical research in acute renal failure and continuous renal replacement therapies. His training combined practical experience in a clinical research project with a core curriculum in clinical research methodology.

In 2015, Dr. Claure-Del Granado organized a CME meeting, ‘YNC 0by25 Workshop’ on AKI, in Santa Cruz de la Sierra, Bolivia, in collaboration with the Bolivian Society of Nephrology. In 2019, he arranged the 12th International Bolivian Congress of Nephrology. This meeting provided a comprehensive review of advances in clinical care and research in AKI, CKD, and Kidney Transplant and featured three workshops including a hands-on workshop on Hemodiafiltration.

Dr. Claure-Del Granado was chair of the Young Nephrologists Committee from 2016-2018. He is currently a member of the @ISNeducation Team, the WCN 2020 Social Media Team, the YNC, and the Fellowship Committee. He is Emerging Center Leader for the ongoing SRC partnership between Hospital Obrero #2, C.N.S./Universidad Mayor de San Simon in Bolivia and the University of California, San Diego as well as Site Leader for the Kidney Care Network project.

Mirna Aleckovic-Halilovic, from the Clinic of Internal diseases at the University Clinical Center Tuzla in Bosnia and Herzegovina, trained for six months under Dr. Ahmed Aimun at the Royal Preston Hospital in the UK in 2015. An SRC pairing was also established between these institutions. Dr. Aleckovic-Halilovic acknowledged the advantage of being able to participate in both these programs simultaneously, stating that they “benefit each other in so many ways and facilitate achieving [the] purposes of both.”

Dr. Aleckovic-Halilovic was able to improve transplantation medicine in both her home institution and in her home country as a whole by adopting a higher quantity of biopsies using new biopsy techniques. She shared her expertise through research and publications and assisted colleagues from Bosnia and Herzegovina and Croatia in their applications for ISN Fellowships.

Dr. Aleckovic-Halilovic joined the Young Nephrologists Committee and became a member of the Eastern and Central Europe Regional Board in 2017 and a member of the ISN Clinical Research Committee in 2019.

Last year, she organized a week-long Educational Ambassador visit by Dr. Ahmed Aimun on Glomerular Diseases with a focus on hands-on training in Kidney Biopsy.

Apply for an ISN Fellowship here.

Milestones in Nephrology Issue 2: Systemic autoimmune diseases and the kidney

To celebrate ISNs 60th anniversary, Kidney International’s “Milestones in Nephrology” series continues with a review of some of the original articles it has published on the effects of systemic autoimmune diseases on the kidney.

These articles have characterized the pathology and clinical course of these diseases and enabled the nephrology community to make informed decisions in treating these complex conditions:

  • The glomerular basement membrane as antigen: Goodpasture’s syndrome and anti-GBM glomerulonephritis (Wilson CB, Dixon FJ., 1973);
  • Severe GN but few glomerular antibodies: pauci-immune GN (Pusey CD, Rees AJ, Evans DJ, et al.);
  • Assessing the prognosis of lupus nephritis: the role of the kidney biopsy (Austin HA III, Muenz LR, Joyce KM, et al.); and
  • Personalizing immunosuppressive treatment in LN (Dooley MA, Hogan S, Jennette JC, et al.).
Thursday, 06 February 2020 12:09

ISN Welcomes a new Collective Society

ISN Welcomes a new Collective Society

In January, the Panamanian Society of Nephrology and Hypertension (SPNH)  joined ISN as a Collective Society, further strengthening a mutual commitment to the advancement of nephrology in Central America.

Collective Society status increases global activity and visibility through ISN endorsement giving priority consideration for managing joint events and complimentary participation in the Global Village at the World Congress of Nephrology (WCN).

ISN looks forward to working closely with the SPNH to advance kidney health worldwide – together.

If you would like more information about the benefits of collective membership, please send an email to membership@theisn.org.

“8 Golden Rules Challenge” for World Kidney Day 2020

On February 8, WKD launched #MyGr8Rule challenge urging everyone around the globe, of all ages and from all cultures, to look after their kidneys and prevent kidney disease.

To participate in the #MyGr8Rule challenge:

  • Accomplish one of the 8 golden rules of keeping kidneys healthy and preventing kidney disease such as keeping active, quitting smoking, eating a healthy diet etc.
  • Take a picture of yourself in action
  • Layer the Rules photo frame on top of your photo (optional)
  • Share on social media with the hashtag #MyGr8Rule

Involve family and friends to creatively complete as many #MyGr8Rule challenges as possible in anticipation of WKD on March 12.

Discover the WKD 8 golden rules and get inspiration here.

ISN represented at the Global Noncommmunicable Disease Alliance Forum

The third Global Noncommunicable Diseases Alliance (NCDA) Forum is being held in Sharja, UAE, from February 9 to 11, 2020. ISN, a partner of the NCDA, joined the Forum to represent kidney diseases worldwide.

The theme of the Forum was “Bridging the Gap” and focused on ways to accelerate the translation of political commitment into action, especially in light of the Political Declaration on NCDs (2018) and UHC (2019).

On February 10, ISN Advocacy Director Luisa Strani opened the workshop, “Building coalitions and social movements to address NCD multi-morbidities: Health systems for people, not siloes for diseases,” and moderated the discussion on the opportunities and challenges of developing an integrated approach to NCDs.

The ISN is a strong advocate of an integrated and people-centered approach to care, both key elements in reducing the multi-morbidity burden of kidney diseases and to achieve Universal Health coverage (UHC).

Follow ISN advocacy activities here.

ISN Clinical Research Program: Call for Applicants 2020

The ISN Clinical Research Program supports research and education programs in low-to-middle income countries, involving local nephrologists, health workers, and authorities. The Program helps implement research projects to detect and manage non-communicable chronic diseases such as CKD, AKI, hypertension, diabetes, and cardiovascular disease.

The deadline for online submission of proposals is May 1, 2020.

Proposals must be reviewed by a regional coordinator for approval before they are submitted online. To ensure adequate reviewal time, proposals should be sent to the regional coordinator before April 1, 2020.

Please access the online application platform before you contact your regional coordinator to see how project proposals should be written and what documentation is required.

Download the detailed Clinical Research Program Guidelines here for more information and eligibility.

ISN looks forward to supporting research projects that will help detect and manage non-communicable chronic diseases in emerging countries.

A two-day meeting was held in Vancouver, Canada, from January 31 to February 1, 2020, which brought together the ISN executive leadership, members of ISN Research groups, patients, clinicians, clinical trialists, academics, industry, and regulators to establish momentum for international collaborative work in clinical trials and research in kidney disease across the world.

The meeting introduced current ISN research activities and described the overall landscape in international clinical research. Six patient partners shared their kidney journeys and their perspectives on participating in research. The focus of the meeting was to present, vet, and clarify draft definitions of kidney failure as endpoints in clinical trials, and to understand the nuances and issues related to different definitions, in specific circumstances, in order to achieve international consensus.

A publication is being drafted, which will describe the recommended components of kidney failure endpoints for use in clinical trials, based on the totality of the work done by the conference participants. Dissemination activities are subsequently planned.

This is the first attempt by the international nephrology community to identify reproducible, robust definitions of kidney failure outcomes and acceptable surrogates for clinical trials, to be used worldwide, in any resource setting. The value of these consensus definitions will be to improve consistency and understanding of results in clinical trials. This is a first step toward a long-term goal to improve the evidence base from which to treat patients with kidney diseases worldwide.

This initiative is part of ISN’s recognition of the importance of clinical research and the need to enhance clinical trials based on established endpoints with international relevance. 

As part of its vision to ensure equitable access to kidney health globally, the International Society of Nephrology (ISN) is proud to launch the Emerging Leaders Program (ELP). With the aim of building a global talent pool of future leaders, the ELP welcomes ISN members interested in shaping the direction of kidney health through professional development and improved understanding of health policy and implementation to ensure health promotion and access to prevention, control and management of kidney diseases.

The Program will provide participants worldwide with the opportunity to work closely with international experts in order to develop leadership and advanced capabilities in:

  • implementation science and research;
  • developing and implementing evidence-informed policy;
  • evaluation, development and management of health systems;
  • principles of entrepreneurship, advocacy and communications;
  • influencing stakeholders including policymakers, funders, implementers and media.

To participants, the ELP offers (1) becoming part of a global network consisting of experts who positively impact the kidney health agenda around the world through collaboration as well as high quality and multidisciplinary research in discovery and implementation science; (2) empowerment to find innovative ways to let their voices be heard so they can act as agents of change at the local and international level and (3) access to continuous professional development to acquire the necessary resources, skills and knowledge to take on leadership roles locally and globally

Successful candidates will be matched with a mentor drawn from the ISN leadership to help them map out their journey and reach their career goals.

Eligibility Criteria:

  • Early career academic (MD and/or PhD) as defined by being at the Fellow/Instructor/Assistant Professor level or equivalent for other countries.
  • The call is open to non-academics at comparable career levels who are interested in improving the global kidney health agenda.
  • Talented and motivated early-career professional (less than 10 years out of residency or training)
  • Be able to demonstrate commitment to the improvement of global kidney health using a collaborative approach.
  • Be a member of ISN (Not a member? Join here)

Information Session and Applications
An information session will be scheduled to take place at the World Congress of Nephrology in Abu Dhabi (26-29 March 2020). The application session will open shortly after the Congress.

If you would like to attend the information session or ask questions about the program, please contact Marie-Pierre Smal at mpsmal@theisn.org

Monday, 27 January 2020 11:45

Young Nephrologists at WCN20

The World Congress of Nephrology in Abu Dhabi is fast-approaching. The Young Nephrologist Committee has put together an exciting program of sessions and events tailored specifically to young nephrologists and trainees:

Young Nephrologists Session

Saturday 28th March: 12 p.m. - 1 p.m., Capital Suite 5

Learn about the challenges and experiences of young nephrologists from around the world.

Talks will be given by young nephrologists from Lebanon, focusing on the challenges facing young female nephrologists in the Middle East, and from Uganda, on their experiences of the ISN Fellowship Program. And the winners of the young nephrologist abstract awards will present their work. This session will also include an update on the activities of the Young Nephrologist Committee and its objectives going forward.

Young Nephrologists Highlights Session

Sunday 29th March: 10 a.m. - 10.45 a.m., Spotlight Theatre (venue to be confirmed)

Find out how to become involved in ISN initiatives.

This informal and interactive session at the Spotlight Theatre will be an opportunity to hear about different ways young nephrologists can become actively involved with the work of ISN. This will include a talk from Pierre Ronco, the editor of Kidney International, outlining opportunities for publishing in ISN’s journals. Other ISN programs, such as the Fellowship Program and the Sister Renal Centers Program, will be showcased.

Young Nephrologist Social Event

Saturday 28th March: 5.30 p.m., Pearl Rotana Capital Centre

Network with young nephrologists from ISN’s global community.

The Pearl Rotana Capital Centre (www.rotana.com) has been specially designated for young nephrologists attending WCN20 in Abu Dhabi. This hotel is very close to the convention center and offers good rates; so do join other young nephrologists here if you haven’t yet booked accommodation.

A social event for all young nephrologists and trainees will be held here. Scientists, patients, and other healthcare professionals are warmly invited to join. This will be an informal occasion presenting an opportunity to meet other young nephrologists from around the world. This event was a great success in Melbourne, and ISN would love to see as many of you as possible again this year.

To encourage an international online community where ideas can be exchanged amongst young nephrologists from around the world, please remember to use the hashtag #ISNYoung for all content relevant to young nephrologists on social media at all times, including at the Congress.

 

See you in Abu Dhabi,

The Young Nephrologists Committee

A two-day meeting is to be held in Vancouver, Canada, from January 31 to February 1, 2020, bringing together members of ISN Research groups, patients, clinicians, clinical trialists, academics, industry, and regulators to establish momentum for international collaborative work in clinical trials and research in kidney disease across the world.

The meeting will introduce current ISN research activities and describe the overall landscape in international clinical research. The core focus of the meeting is to establish the 1st International Definition of Kidney Failure in Clinical Trials Consensus Document, with publication and dissemination to follow.

This is the first attempt by the international nephrology community to identify a reproducible, robust definition of kidney failure for clinical trials, to be used worldwide, in any resource setting. The value of this consensus definition will be to improve consistency and understanding of results in clinical trials. This is a first step toward a long-term goal to improve the evidence-base from which to treat patients with kidney diseases worldwide.

This initiative is part of ISN’s recognition of the importance of clinical research and the need to enhance clinical trials based on established endpoints with international relevance.

iran society

Below, Left to Right: 1. Mohsen Nafar (President of IrSN and Congress), 2. David Harris (Past-President of ISN), 3. Shahrzad Ossareh (Chair of Middle East Regional Board of ISN, Secretary General of IrSN), 4. Behrooz Broumand (Past President of IrSN), 5. Ghanbarali Raeisjalali (Iranian Nephrologist), 6. Mohammadali Shafiee (Iranian Nephrologist, Canada), 7. Jose Divino (Nephrologist, Brazil)

The Iranian Society of Nephrology (IrSN) hosted its 17th International Congress of Nephrology, Dialysis & Transplantation in Tabriz, in northwest Iran, from 19-22 November, 2019.

The conference was organized in collaboration with ISN, represented by Past President and current Chair of ISN Programs, David Harris, The International Pediatric Nephrology Association (IPNA), the Mayo Clinic Foundation, the Iranian Society of Pediatric Nephrology, and Tabriz University of Medical Sciences.

IrSN, one of the largest collective societies of ISN, has kept pace with the rapid progress in the science of nephrology and is well-placed to help build capacity in the field in neighbouring, emerging countries, and this is being progressively achieved.

Due to the disruption of internet services in Iran at the time of the Congress, the meeting was not live-streamed on the ISN website as planned. However, the full program is now accessible on the ISN Academy.

More photos are available here.

A multidisciplinary group of researchers and clinicians met in October 2018 to identify evidence and address controversies in potassium management providing research priorities and guidance for evaluation and management of dyskalemias in the context of kidney diseases.

Celebrate World Kidney Day (WKD) by organizing an awareness event in your community: a sports event, a concert, a roundtable talk, a flash mob, or even a street fest.

If you need help organizing a World Kidney Day event, download the 2020 “events guide”. If you’ve already planned your event, please add it to the interactive worldwide map.

Follow World Kidney Day social media channels (@worldkidneyday, worldkidney_day, @worldkidneyday) to take part in a fun interactive activity next month celebrating 15 years of WKD (#gr8).

Tuesday, 21 January 2020 14:00

Simulation Certificate Course in Abu Dhabi

Given the steadily increasing demand for interventional nephrology in low and middle-income countries, the ISN, with generous support from Cleveland Clinic, will hold a simulation training session from 8 a.m. to 12.30 p.m. on Friday, March 27, 2020, in Abu Dhabi.

The course focuses on learning and practicing procedures, such as central venous catheter placement, kidney biopsies, and physical examination of vascular access under supervision. The aim is to offer supervised training to help students feel comfortable performing the procedures. This course is separate from the Interventional Nephrology pre-course taking place on Thursday 26 at WCN20.

As a component of this course in Abu Dhabi, ISN will shortly release an online didactic module designed for general nephrologists, nephrology trainees, advanced practitioners, nephrology nurses, and technicians. It will provide an overview of vascular access biology, process of care, identification of complications, and fundamentals of quality improvement goals. To receive the “Mastery in Simulation Training” certificate, this online module must be completed and a supervised simulation training must be passed prior to the hands-on training session in Abu Dhabi.

The registration fee for the course is $1,000. Cleveland Clinic has generously agreed to sponsor the course fee for 15 trainees from low to middle-income countries. The sponsored delegates will be recognized as Brenda and Tim Huval Interventional Nephrology Scholars.

The course has a maximum capacity of 30 people. If you would like to participate in the course, please complete the registration form and send to isnprograms@theisn.org before March 3.


Supported by CCF

Registration Form

In honor of the late influential nephrologist and former Editor of Kidney International Detlef Schlöndorff, ISN has set up the Detlef Schlöndorff Fellowship Fund to support training for one Fellow per year.

The ISN congratulates Dr. Etienne Ntabanganyimana, from the Gihundwe Hospital in Rwanda, who has been selected as the first Detlef Schlöndorff Fellow by the ISN Fellowship Committee.

Dr. Ntabanganyimana will travel to India to spend 12 months training under the mentorship of Prof. Santosh Varughese at the Christian Medical College in Vellore. His training will focus on Interventional Nephrology.

The ISN wishes to thank Barbel Schlöndorff, wife of the late Detlef Schlöndorff, Patricia and Jeremiah Morrissey, and Pierre Ronco for their generous donations toward funding this fellowship.

Donations to the Detlef Schlöndorff Fellowship Fund can be made by PayPal. If you would like to make a donation by check or bank transfer, please contact Thomas Jacob, ISN Fellowship Program Coordinator, by email at Tjacob@Theisn.org.

Tuesday, 21 January 2020 13:54

Access the latest ISN-ACT Global Trials

Every month the ISN-ACT Team lists interesting new randomized controlled trials from around the world.

Highlights:

  • Brace for it: an external support device may help fistulas to mature
  • Getting things straight when it comes to peritoneal dialysis catheters

See the latest trials here

In the second half of 2019, ISN led two meetings in Colombia providing education on pediatric and adult kidney transplantation and patient accessibility to renal transplantation services.

The ISN-Transplant Society (TTS) Sister Transplant Center (STC) pair, Boston Children´s Hospital and ISN emerging center Fundación Valle del Líli in Cali, Colombia, held a meeting on the immunopathology of kidney transplantation from August 27-28, 2019, in Cali Colombia. This meeting was part of the ISN Continuing Medical Education Program (CME). The guest speaker, Dr. Andres Jaramillo, Director of the Histocompatibility Laboratory and Associate Professor of Laboratory Medicine and Pathology at the Mayo Clinic in Arizona, gave several talks over the course of the two-day conference, which included a workshop and laboratory in immunopathology of kidney transplantation.

The ISN Sister Renal Center (SRC) trio, ISN mentoring center Boston Children’s Hospital, ISN supporting center Fundacion Valle del Líli, and and ISN emerging center Hospital Susana López de Valencia in Popayàn, in collaboration with the Colombian Association of Nephrology (ASOCOLNEF) and the Colombian Pediatric Nephrology Association (ACONEPE) held a second meeting on acute and chronic kidney disease, “Renal health for everybody, everywhere”, from October 25-26, 2019, in Popayàn, Colombia. Dr. Francisco Flores, associate professor and consultant at Cincinnati Children’s Hospital, USA, was an invited speaker at the event.

According to Dr. Restrepo, the region faces several challenges: the mortality rate of acute kidney disease is high and more training in AKI detection and treatment is needed; there are difficulties communicating with the large aboriginal population with renal diseases in the Southwest region, and Cali is a long distance drive for many, with few direct planes. Popayàn has almost 650 patients in renal replacement therapy (RRT), and Pasto has 900 patients in RRT waiting for kidney transplantation (KTx).

Following these meetings, Popayan received the support necessary to start academic meetings and workshops to enhance RRT and stimulate interest for these programs among the medical population.

Drs. Andrés Jaramillo and Jaume Martorell from the Hospital Clinic, Barcelona, and Edgar Milford from Brigham and Women’s Hospital, Boston, support the Fundación Valle del Líli’s kidney immunopathology and tissue typing laboratory development. Plans are currently being made to set up two additional transplant centers in Popayan and Pasto. The ISN SRC and ISN-TTS STC Programs have supported and trained nurses, laboratory professionals, as well as adult and pediatric nephrologists toward launching the transplant program in Popayàn.

To celebrate ISN’s 60th anniversary throughout 2020, Kidney International’s “Milestones in Nephrology” series launches with a review of the development in understanding of the pathophysiology of the glomerulus, highlighting several original articles published in KI:

The glomerular signature in patients with hematuria (Kenneth F. Fairley and Douglas F. Birch, 1982);

The permselectivity of the glomerular capillary wall (Ramsay L.S. Chang, William M. Deen, Channing R. Robertson, and Barry M. Brenner, 1975);

T-cells and macrophages in rapidly progressive glomerulonephritis: clinicopathologic correlations (Bolton W.K., Innes D.J. Jr., Sturgill B.C., Kaiser D.L., 1987);

Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis (Yoshida Y., Fogo A., Ichikawa I., 1989); and

Genetic studies into inherited and sporadic hemolytic uremic syndrome (Warwicker P., Goodship T.H.J., Donne R.L., et al., 1998).

These articles, despite sometimes triggering controversy, opened the way for improved patient care, innovative therapeutic intervention, and genetic screening.

These groundbreaking papers from KI, shared monthly, will be discussed by an editor from KI and put into perspective of the most recent advances in the field.

Celebrating ISN’s 60th anniversary, this online timeline spans six decades of ISN’s remarkable history of commitment to advancing kidney health worldwide.

Follow ISN’s journey starting as a small community of visionaries with little funding to a global organization dedicated to improving kidney care worldwide through granting programs, education, research, and advocacy.

At the advent of its seventh decade, ISN is confident that members and partners will continue to work together toward equitable access to kidney health for all, adding new chapters to an enduring history.

The 38th edition of the International Vicenza Course on Acute Kidney Injury and Continuous Renal Replacement Therapies will be held from May 26-28, 2020, in Vicenza, Italy.

This scientific event will host an AKI path, a CRRT path, and a Meet the Expert path, as well as a series of lectures and panel discussions led by world experts in the field. The course will provide a valuable opportunity for discussion between peers and experienced colleagues to improve care for patients with acute kidney injury and multiple organ dysfunction.

Three complimentary passes to attend the event are available to young nephrologists under the age of 35 who are ISN members. Please note that travel and accommodation are not included in this offer. The ISN Young Nephrologists Committee will select the successful applicants. The deadline to apply is February 28, 2020.

Application Form

For further information, please contact mgallardo@theisn.org.

Dear colleagues,

The start of the new year provides us with the opportunity to look forward to the International Society of Nephrology's ongoing work, guided by its mission of advancing kidney health worldwide and the shared values of the ISN membership.

ISN’s capacity building and educational activities have helped build a critical mass of appropriately skilled professionals providing kidney care in parts of the world where such services are most needed. This has been possible through a global pool of volunteers who continue to selflessly share their expertise and knowledge.

ISN is committed to further enhance the capacity of a global nephrology workforce with the aim of building leaders who will not only advance in their own careers but work collaboratively to create integrated, scalable, and sustainable kidney care programs aligned with their national health priorities, as well as with global standards.

ISN’s efforts in helping to build leaders will be supplemented by strong and enhanced advocacy focus on an integrated approach to kidney care, as part of universal healthcare, in partnership with other professional societies, NGOs and multilateral organisations.

ISN is dedicated to enhancing the global nephrology community's participation in research, particularly in high-quality clinical trials and cohort studies, through activities that increase collaboration and sharing of experiences.

I want to thank each one of you for your contribution to making ISN a trusted leader, effective enabler, and connector of communities. The ISN's priorities are those of its members, and we look forward to hearing from you - either reaching us directly through the ISN Regional Boards or the leadership of your national and regional societies of nephrology.

I am honored to be serving as the ISN President in this 60th year of our society. I look forward to welcoming many of you at WCN20 in Abu Dhabi in March, and to the always lively and stimulating interchanges that take place at the Congress. 

Finally, I wish you the best for 2020, and look forward to working together for a future where all people have equitable access to sustainable kidney health.

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Banner for 60th anniversary Version 2 Announcement

The celebratory activities to mark ISN’s 60th anniversary in 2020 have been launched.

Throughout 2020, ISN will highlight past accomplishments, current projects, and future aspirations in its mission to advance kidney health worldwide.

Some of the activities taking place in our 60th year are:

  • a series of articles, “Milestones in Nephrology”, published in ISN journal Kidney International, highlighting 60 groundbreaking papers that helped change and advance the field of nephrology
  • a number of events and special announcements at the World Congress of Nephrology (WCN) in Abu Dhabi on March 26-29, 2020
  • a celebration of key developments in nephrology in different parts of the world on org throughout the year
  • new content on the ISN Academy
  • anew ISN logo and redesigned website

Follow us on social media to discover more #ISN60years

ISN is pleased to announce a new partnership with the Alder Hey Children's Hospital in Liverpool, United Kingdom, supporting one long-term Fellowship per year to train in pediatric nephrology. The collaboration seeks to contribute to the development of renal care in low and middle-income countries.

To start with, candidates will need to establish a training plan with a Host Mentor at the Alder Hey Children’s Hospital and outline the objectives of the training by February 1. Once the curriculum has been agreed, candidates can apply on the ISN Fellowship application portal by May 1.

More information on application requirements is available here.

Monday, 16 December 2019 09:31

ISN Welcomes Two New Collective Societies

The Colombian Association of Nephrology and Arterial Hypertension (ASOCOLNEF) and the Paraguayan Society of Nephrology (SPN) have joined as ISN Collective Societies, further strengthening a mutual commitment to the advancement of nephrology in the Latin American region.

Members of the SPN and ASOCOLNEF will enjoy the full benefits of ISN membership for a tailored fee. Collective Society status increases global activity and visibility through ISN endorsement, priority consideration for managing joint events, and complimentary participation in the Global Village at the World Congress of Nephrology (WCN).

In addition, individual members of these societies enjoy full membership benefits including special event rates journals, special event rates, and education at the ISN Academy.

ISN looks forward to working closely with ASOCOLNEF and PSN to advance kidney health worldwide – together.

If you would like more information about the benefits of collective membership, please send an email to membership@theisn.org.

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