Day 1

Day 1 – June 23, 2022


11:00 ISN Welcome Speech Agnes Fogo      USA
11:10 Welcome from the 2022 ISN Frontiers Meeting Chairs Giuseppe Remuzzi Italy
Marina Noris Italy
Raja Ramachandran India
Plenary Lecture
11:15 Rare Renal Diseases of Complement Dysregulation: Open a Window on the Future of Medicine Giuseppe Remuzzi Italy
Immune Complex Associated Membranoproliferative Glomerulonephritis and C3 Glomerulopathy

Session 1:

What Have We Learnt from Animal Models?

12:00 The Complement System and the Kidney in Humans and Rodents Richard Quigg United States
12:20 Mouse Models of C3G: Role of C3 and C5 Activation Products Matthew Pickering United Kingdom
12:40 Q&A Discussion
Lunch break 13:00 Lunch and poster viewing

Session 2:

Advances in Pathophysiology

13:50 Genetic Basis: CFHR Hybrids Peter Zipfel Germany
14:10 Genetic Basis: The Role of Rare and Common Complement Gene Variants Rossella Piras Italy
14:30 Nephritic Factors and Anti-complement Futoantibodies Sophie Chauvet France
14:50 Oral presentation from abstract selection:
The three C-terminal domains of FHR1 influence complement activation and FHR1 cooperation with other complement regulators
Luce Perie Germany
15:00 Q&A Discussion
Coffee break 15:20 Coffee break and poster viewing

Session 3:

Clinical – Unanswered Questions

15:50 The Variable Expression of C3G/IC-MPGN: Complement, Post-infectious, Paraproteins Moglie Le Quintrec-Donnette France
16:10 Maths Helps Clinicians with Making a Diagnosis and Predicting Outcomes Marina Noris Italy
16:30 Oral presentation from abstract selection
Artificial Intelligence Assisted Quantification of Complement Convertases in Glomerulonephritis
Luce Perie Germany
16:40 Oral presentation from abstract selection
Outcome of Kidney Grafts Transplanted for C3 Glomerulopathy and Membranoproliferative Glomerulonephritis
Matthieu Halfon  Switzerland
16:50 Q&A Discussion
Keynote Lecture 17:20 C3G/IC-MPGN in 2022 Richard Smith United States
Welcome Reception 18:00 Welcome Reception