Clinical Trials (ISN-ACT)

The ISN-Advancing Clinical Trials (ISN-ACT) is an ISN initiative to encourage existing infrastructures within ISN to improve the global nephrology community’s participation in clinical trial research.

ISN-ACT calls on investigators and interested individuals to join the initiative to generate more high-quality clinical trials and studies in nephrology, informing the optimal prevention and treatment of kidney disease and its complications for the benefit of patients.

The ISN calls on members to help grow the capacity of the global nephrology community to lead and participate in clinical trials, by contributing, collaborating, and sharing experience.

  • Facilitate collaboration by connecting people undertaking clinical trials and related studies in nephrology.
  • Provide a forum to discuss key scientific, operational, and analytical issues facing clinical trial researchers in kidney disease.
  • Increase the capacity to conduct high-quality clinical trials and studies in nephrology through ISN training and by connecting experienced and novice researchers.
  • Develop ISN led or supported activities that help standardize high-quality trial conduct in nephrology.

ISN-ACT Global Trials Focus (GTF)

The ISN-ACT Global Trials Focus is a monthly list identifying and summarizing recent interesting trials relevant to kidney disease.

View previous GTFs, the Trial of the Month in other languages and the GTF on the ISN Academy e-learning platform here.

For those reading the results of research studies, it is essential to be able to appreciate the key points, methodology, real life application and policy significance of this study. It is also important to understand whether there are problems or limitations with the results, whether and how the study was conducted in the best way possible, i.e., to get an answer to a question under investigation with minimum bias or risk of incorrectness or inaccuracy. For these reasons, going forward, different studies presented in the ISN-ACT Global Trials Focus (GTF) will be reviewed and explained in a way that helps all readers, no matter their degree of scientific knowledge, to appreciate some of these key points.

Through this collaboration of ISN-ACT GTF contributors with people living with kidney disease, we hope to contribute to a better awareness and understanding for all, of latest research relevant to kidney health and care, to enable meaningful communications between healthcare providers and people living with kidney disease, to facilitate advocacy efforts and finally, to encourage more participation in important clinical trial initiatives.

Pin Your Trial Network on the ISN Network of Trial Networks Map!

The ISN-ACT (Advancing Clinical Trials) has created an online map tracking trial networks in kidney care research around the world.

The aim is to facilitate clinical trial capacity and professional exchanges and collaboration by connecting people undertaking clinical trials and related studies in nephrology.

The map allows researchers to quickly locate trial networks with the capacity to carry out trials and promotes trials to improve outcomes for people with kidney disease.

Find out more about the networks involved and explore the map here.

This map is an ongoing initiative. To showcase your trial network on this map, contact us at 

Interested in joining the ISN-ACT Network?

Watch how to sign into ISN networks here.

Apply here.

For all inquiries on ISN-ACT, contact the ISN Research Team at

Meet the ISN-ACT Committee and Core Group Members here.