Infographic on the Complement System and Related Kidney Diseases, with narration
Animation on the Complement System and Related Kidney Diseases, with narration
Content will continue to be added throughout the year. Make sure to check back!
C3G
Overview C3G Infographic
In-Depth C3G Infographic
All of the recorded versions of the pre-webinar series leading up to KDIGO’s Controversies Conference on the Role of Complement in Kidney Disease can be found below.
Webinar 1: Dissecting the Role of Complement in Glomerulonephritis with a Focus on C3G
Webinar 2: What’s New in the Management and Treatment of GN: A look at ANCA and LN
Webinar 3: What’s New in the Management and Treatment of Glomerulonephritis: A look at IgAN and MN
Webinar 4: Role of Complement Beyond Glomerulonephritis (transplantation, DKD)
ISN Global Kidney Care Podcast on CMKDs
In this podcast, Drs Namrata Parikh, Gary Chan and Nick Medjeral-Thomas discuss key clinical and pathology features of inappropriate, pathogenic complement activity that guide physicians to a diagnosis of C3 glomerulopathy. They discuss differences in investigation and management strategies between their respective clinical centers in Ottawa, Hong Kong and London, including access to clinical trials of therapeutic complement inhibitors. To finish, they speculated on the future impact on clinical nephrology of complement pathway analysis and inhibition.
ISN Quiz on Complement mediated Glomerulopathies
ISN October 2022 eDigest on CMKDs
ISN’s October ’22 eDigest presents recent publications in Kidney International Reports on the pathophysiology, progression, treatment, and validation of complement-mediated kidney diseases. It also highlights four original papers, in the field of complement-mediated kidney diseases, that have been published in Kidney International within the past few months. Explore the eDigest here.
ISN Frontiers Webinars
Dr. Vladimír Tesař, Dr. Sydney Tang and Dr. Liz Lightstone provide expert guidance on the ongoing development of the toolkit; supported by Dr. Gary Chan, Dr. Namrata Parikh and Dr. Nicholas Medjeral-Thomas.
Vladimír Tesař
Vladimír Tesař is a head of the Department of Nephrology, 1st Faculty of Medicine, Charles University in Prague, Czech Republic. He is a member of the ISN Council Executive Committee and was chair of the Immunonephrology Working Group at ERA-EDTA from 2015 – 2021. He is the publications-author or co-author of more than 450 publications and is a member of the editorial board of Nephrology Dialysis Transplantation and Clinical Journal of the American Society of Nephrology.
Sydney Tang
Sydney Tang is currently Chair of Renal Medicine and Yu Professor in Nephrology at The University of Hong Kong. He is the President of the Asian Pacific Society of Nephrology, Executive Committee of KDIGO, and Chair of the CME Program Committee of the ISN. He is a past Chairman of the Hong Kong Society of Nephrology and serves the Hong Kong College of Physicians as Council Member (co-opt) and Secretary and Program Director (HK Island) of the Specialty Board in Nephrology.
Liz Lightstone
Liz Lightstone is Prof of Renal Medicine at Imperial College London. She is an elected member of the Women in Nephrology Executive Council. She is global co-chair of the SONG-GD steering committee, co-chairs the UK Kidney Research Consortium GN Clinical Study Group, established the Renal RaDar CKD and pregnancy rare disease group, is a member of the OMERACT 2022 SLE Working Group and the International Working Group on Glomerular Diseases and Pregnancy. She is a Trustee of Kidney Research UK and serves on their Research Strategy and Nominations and Governance Committees. She is a mentor on the 2021 ISN Emerging Leaders Programme.
Gary Chan
Gary Chan is currently an Associate Consultant and Honorary Clinical Assistant Professor at Queen Mary Hospital in Hong Kong, where he is in charge of the Acute Glomerulonephritis Clinic and the Genetic Kidney Disease Clinic. He is also the Training Programme Director for Nephrology at Hong Kong West Cluster Hospitals, Chair of the Young Nephrologist Committee of the Hong Kong Society of Nephrology and serves on the Continuing Medical Education Committee of the Asian Pacific Society of Nephrology.
Namrata Parikh
Namrata Parikh completed her nephrology training in India and is currently pursuing a fellowship in solid organ transplantation at The Ottawa Hospital, Ottawa, Canada. Her areas of interest are glomerular disease and kidney transplantation. She is a member of the @ISNEducation social media team, as well as a member of the Women in Nephrology – India social media team.
Nicholas Medjeral-Thomas
Nicholas Medjeral-Thomas is a kidney physician and clinician scientist at Imperial College London. His research focuses on the role of complement deregulation in C3 glomerulopathy and IgA nephropathy pathogenesis. He has made a number of important discoveries that improve our understanding of both these conditions. Most recently, he has investigated associations with and the potential pathogenic role of a protein called factor H related protein 5 (FHR5) in IgA nephropathy and C3 glomerulopathy. He has also investigated associations between lectin complement pathway proteins and COVID-19.
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The Complement-Mediated Kidney Diseases Toolkit is supported by Alexion AstraZeneca Rare Disease, Novartis and Roche.
Disclaimer text: This toolkit is intended to facilitate decision making of health professionals in their daily practice. However, final decisions concerning an individual patient must be made by the responsible health professional(s) in consultation with the patient and caregiver as appropriate. The ISN declines any responsibilities for any damage caused by the use that may be made of the information provided in this toolkit.