ISN-PKD Foundation Webinar: Early Diagnosis and Risk Stratification in ADPKD
- 4 PM CET
This webinar will introduce the problem of CKDu, a form of chronic kidney disease primarily affecting young men in rural agricultural communities, with no identifiable link to common causes of CKD. We aim to bring together the leading experts of the ISN International Consortium of CKDu Collaborators (i3C) to share their expertise with the kidney healthcare providers from the NIS and Russia Region. Our speakers will present an overview of the epidemiology, potential etiological factors, clinical spectrum, and management, as well as research methodologies applicable to assess CKDu prevalence.
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disorder, yet general nephrologists often report uncertainty regarding optimal diagnosis, risk stratification, and timing of interventions. This webinar offers a practical, case-based learning experience designed to build confidence in these essential aspects of ADPKD care. Following a concise overview of the disease and highlights from the KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of ADPKD, attendees will engage in virtual grand rounds featuring real-world cases that illustrate key decision points in diagnosis, monitoring, treatment initiation, and referral.
Special attention will be given to use of tools such as the Mayo Imaging Classification (MIC), the PROPKD score, and genetic testing, as well as shared decision-making around therapies like tolvaptan. Participants will leave better equipped to identify rapid progressors, implement timely nephroprotective strategies, and coordinate multidisciplinary care.
Learning objectives:
- Recognize and accurately diagnose ADPKD early in its course, including in atypical or incidental presentations.
- Apply risk stratification tools such as the Mayo Imaging Classification and PROPKD score to guide management decisions.
- Initiate timely interventions, including blood pressure control, dietary interventions, tolvaptan, and understand criteria for selecting appropriate candidates.
Moderator
Sola Bahous (Lebanon)
Speakers
Fouad Chebib (USA)
Christopher Kwoh (USA)