- July 18, 2025
- Acute Kidney Injury, Chronic Kidney Disease, Dialysis, Pediatric nephrology
ISN TrialWatch | June – July 2025
Stronger Together: Finerenone & Empagliflozin Boost Kidney Outcomes in Diabetes
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes
The CONFIDENCE trial was a double-blind, randomized study enrolling 800 participants with chronic kidney disease (CKD) (eGFR 30–90 ml/min/1.73 m²), albuminuria (urinary albumin-to-creatinine ratio [UACR] 100– 5000 mg/g), and type 2 diabetes, all of whom were receiving renin–angiotensin system inhibitors. Participants were randomly assigned in a 1:1:1 ratio to...
