Training
- Field teams should receive training in case detection, standardized clinical assessment, harmonized data collection, and appropriate referral pathways, consistent with i3C recommendations.
- Field teams should receive training which includes ethical conduct of research in vulnerable populations, informed consent, and communication of uncertainty, particularly when invasive procedures or experimental interventions are considered.
- Principal investigators and/or study leads should receive targeted training on epidemiologic methods, exposure assessment, and molecular and genetic sampling approaches should be provided, as appropriate to study objectives. · Existing ISN educational resources and modules, such as ISN Academy CKDu-related content, should be utilized to support capacity building and standardization across sites.
Equipment and resource preparation
- Basic clinical and laboratory infrastructure required for CKDu detection, including standardized creatinine measurement, urinalysis, and blood pressure assessment, should be made available.
- Resources for biospecimen collection, storage, and transport should be planned and aligned with molecular and genetic study objectives where applicable.
- Access to renal pathology services should be assessed and strengthened before initiating biopsy-based studies, including training, quality assurance, and safe sample handling.
- Resource planning should be aligned with realistic intervention and implementation pathways, recognizing that limited infrastructure may constrain both research and subsequent intervention testing.