ISN Journal summaries on B cell-targeting immunotherapies and eGFR slope in the cardiorenal continuum
Kidney International® Tiny warriors, big impact: targeted immunotherapy in kidney diseases This review examines whether emerging B cell-targeting immunotherapies, particularly chimeric antigen receptor T-cell therapy and T-cell engagers, could improve outcomes in autoimmune kidney diseases where current treatments often fail. It summarizes early evidence, mainly from small uncontrolled studies in systemic lupus erythematosus, suggesting these approaches may achieve deeper B-cell depletion...