Research

Explore the Reshaped ISN International Network of Chronic Kidney Disease Cohort Studies (iNET-CKD) Network Map

The newly updated ISN iNET-CKD Network cohorts map features a new layout, revised information on cohorts, and additional data. Access the ISN iNET-CKD Network cohorts map here. The ISN iNET-CKD Network is one-of-a-kind. It tracks ongoing chronic kidney disease (CKD) cohort studies located worldwide, facilitating an exchange of insights into CKD progression and its global implications. This network's...

Read the Latest ISN Journal Editorial Selections

Kidney International® Repurposing Drugs for Diseases Associated With Podocyte Dysfunction Due to recent advances in understanding the molecular and cellular mechanisms underlying podocyte injury, there is potential for repurposing already approved therapeutics for treating these disorders. This mini-review explores the complexities of repurposing drugs for kidney treatment, emphasizing the importance of extensive testing, emerging technologies, early intervention,...

Forewarned or Forearmed: Do Automated Medication-targeted Alerts Improve AKI Outcomes? Trial Summary and Commentary

Nikolay Bulanov, ISN-ACT Global Trials Focus Subgroup member, summarizes the design and outcomes of a study from the ISN-ACT Global Trials Focus' most recent global trials selection and comments on the trial's limitations. A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes Summary: In this parallel-group, pragmatic, open-label trial, 5060 hospitalized...

Latest ISN Journal Editorial Selections  

Kidney International® Managing the Symptom Burden Associated With Long-term Dialysis: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference In 2022, patients, doctors, therapists, nurses, pharmacists, and researchers came together at the KDIGO Controversies Conference, “Symptom-Based Complications in Dialysis,” to examine and agree on essential ideas about recognizing and treating symptoms in dialysis patients....

Results From the iNET-CKD Study on Hemoglobin in Global CKD Populations Published in Kidney International Reports®

The "Regional Variation in Hemoglobin Distribution Among Individuals With CKD: the ISN International Network of CKD Cohorts" study, led by ISN iNET-CKD* investigators, addresses anemia's global prevalence in people living with chronic kidney disease (CKD). Read the manuscript here. Current guidelines suggest a uniform hemoglobin (Hb) range for all people with CKD, but this research examines...

High-dose Hemodiafiltration or Hemodialysis for Patients With Kidney Failure? Michele Provenzano on the CONVINCE Trial

Michele Provenzano summarizes the design and outcomes of the ISN-ACT Global Trials Focus’ latest “Trial of the Month” and comments on possible mechanisms of the benefit and limitations of the results. A CONVINCE-ing trial for Hemodiafiltration Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure Reviewed by Dr. Provenzano, ISN-ACT Global Trials Focus Subgroup...

How to Write a Winning Abstract in Ten Easy Stages

Watch the webinar “Winning Steps for a Successful WCN’24 Abstract Submission and Beyond.” It’s abstract submission season! How can you write a good abstract that will get accepted to WCN’24? WCN’24 abstract reviewers Sabine Karam, Magdalena Madero, Roberto Pecoits-Filho and Rob Walker have got you covered! Follow their foolproof advice on writing a winning abstract...

Help Shape the Global Kidney Care Landscape: Download, Use and Share the ISN-Global Kidney Health Atlas Region-specific Summary Slides

The ISN-Global Kidney Health Atlas (ISN-GKHA) team has produced region-specific summary slides from the 2023 ISN-GKHA edition. Access the documents* here: Africa, Eastern and Central Europe, Latin America, Middle East, NIS and Russia, North America and the Caribbean, North and East Asia, Oceania and South East Asia, South Asia, Western Europe. Why are these slides useful? This...

Latest ISN Journal Summaries

Kidney International ® Editorial Selections The Power of “Negative” Experiments: Harry Goldblatt’s Pathway to Discovering How Renal Ischemia Causes Hypertension The author demonstrates that Harry Goldblatt’s willingness to conduct and publish studies with negative outcomes led to a fundamental understanding of blood pressure control within less than a decade of his initial discovery, published in...