Inside the ORIGIN study: Visual and video abstracts on atacicept for the treatment of IgA Nephropathy
Watch the video for an animated explanation of the study based on the visual abstract. These resources were supported by Vera Therapeutics
ISN Journal summaries on CONVINCE trial findings and kidney transplantation in Iran
Kidney International® A health economic evaluation of the multinational, randomized controlled CONVINCE trial: cost-utility of high-dose online hemodiafiltration compared to high-flux hemodialysis Patients with kidney failure often receive either high-flux hemodialysis (HD) or high-dose hemodiafiltration (HDF). Previous research shows HDF may lower the risk of death compared to HD. This study looked at whether the potential health...
KIR publishes on findings from the ISN Western Europe Regional Board survey on preferred meeting formats
Kidney International Reports® (KIR) has published as an article-in-press the results of a survey conducted by the ISN Western Europe Regional Board on preferred scientific meeting formats— in-person, virtual, or hybrid. Explore the survey findings in KIR “Nephrology health professionals' perspectives on their preferred modality for scientific meetings, balancing affordability, sustainability and opportunities to interact...
ISN-GKHA 2023 findings feature in PLOS Global Public Health roundtable
PLOS Global Public Health recently hosted a roundtable with the lead authors of ISN-Global Kidney Health Atlas (ISN-GKHA) articles they published earlier this year. The authors highlight key insights from their research, which examined disparities in the availability, affordability, quality, and access to kidney care services across countries categorized by World Bank income group classifications. Watch...
Optimize trial integrity: New SOP and ethics resources in the ISN-ACT Clinical Trials Toolkit
The ISN-ACT Toolkit now features a section on Standard Operating Procedures (SOPs) in clinical trials to help improve clarity, consistency, and traceability in clinical trial processes. Access the SOP section of the ISN Clinical Trials Toolkit here Contributed by ISN-Advancing Clinical Trials Committee member Paula Andrea Marioli (Argentina) and colleagues, the section includes: Suggested SOP format – a structured guide...
Explore the latest ISN-ACT Global Trials Focus selection featuring a “Trial of the Month” on the role of targeted exercises for children on hemodialysis
ISN-ACT Global Trials Focus editorial team member Neeru Agarwal summarizes the design and outcomes of the latest "Trial of the Month" featured in ISN-ACT Global Trials Focus. Trial of the Month: Effect of muscle stretching and isometric exercises on quality of life in children undergoing regular hemodialysis Khalf-Allah et al., Pediatric Nephrology. 2024 39:3289-3299. Summary In this single-center study, 68...
Global kidney health visualized: Explore the ISN-GKHA interactive map
Launched at WCN’25, the ISN-Global Kidney Health Atlas (ISN-GKHA) interactive map is a powerful visual tool to explore comprehensive global kidney health data from the 2019 and 2023 ISN-GKHA reports. This interactive, searchable platform highlights key trends currently shaping kidney health and care with the potential to drive improvements worldwide. Explore global kidney health...
PLOS articles spotlight ISN-GKHA 2023 findings on the international state of kidney care
PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications. Read the individual papers in PLOS Global Public Health: “Landscape of kidney replacement...
ISN’s Global Kidney Health Atlas 2023 Data Addresses Kidney Care Gaps in Resource-limited Settings
PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications. Read the individual papers in PLOS Global Public Health: “Landscape of Kidney Replacement...
Is Semaglutide a Game-changer for CKD? Insights for the Layperson Into the SMART Trial in the “Guide for Everyone”
The “ISN Global Kidney Trials Insights: A Guide for Everyone,” inspired by the ISN-ACT Global Trials Focus summaries, translates complex trial findings into accessible information. This initiative empowers people living with kidney disease and their caregivers to better understand advancements in kidney care. Access all the simplified summaries here. The latest case study features the SMART...
ISN Journal Summaries on Hypertension-avoidance Strategies and Age-based GFR
Kidney International® A Sub-study of the POISE-3 Randomized Trial Examined Effects of a Perioperative Hypotension-avoidance Strategy Versus a Hypertension-avoidance Strategy on the Risk of Acute Kidney Injury This sub-study of the POISE-3 trial investigated whether a strategy to prevent low blood pressure during surgery could reduce the risk of acute kidney injury (AKI). Researchers randomized 7,307 patients...
Celebrating ISN’s 2024 Publications: Driving Kidney Research for Better Patient Outcomes
As we step into 2025, we reflect on the impactful ISN-led research of 2024. These studies deepen our understanding of kidney health and advance global kidney care as a health priority. Below, we highlight some of the year’s key contributions: An Update on the Global Disparities in Kidney Disease Burden and Care Across World Countries...
Video Abstract: Results From the ORIGIN Phase 2b Study and Open-label Extension
Watch the video here This video abstract was supported by Vera Therapeutics
ISN-ANIO Workshop on Global Clinical Trials in Diverse Populations – Registration Is Open!
The clinical trials workshop will be held on February 5, 2025, at the Pride Plaza Aerocity in New Delhi, India, as lead-up to the ISN World Congress of Nephrology 2025 (WCN’25) from February 6-9, 2025. It is organized by the ISN-ANIO committee, a collaboration between the ISN and the American Nephrologists of Indian Origin...
ISN Journal Editorial Selections on aHUS Management, Rituximab Therapy, Methylmalonic Acidemia, and Rare Kidney Diseases
Kidney International® Outcomes From the International Society of Nephrology Hemolytic Uraemic Syndromes International Forum The 2023 ISN aHUS Forum brought together global experts to discuss key challenges in managing complement-mediated hemolytic uraemic syndromes (HUS), including nomenclature, biomarkers, and treatment protocols. Key areas for future research were identified, such as genetic predisposition, optimal complement inhibitor use, and improving...
Exploring Groundbreaking Research: Introducing High-impact Trials at WCN’25
The High-impact Trials (HIT) sessions at WCN'25 promise exciting insights and findings from cutting-edge research in kidney care and related fields, including: The FLOW Trial investigating semaglutide's impact on kidney outcomes and cardiovascular safety The REGENCY Trial on improving renal response rates in lupus nephritis with Obinutuzumab The ZEUS Trial evaluating ziltivekimab's potential for cardiovascular protection in...
Results of Open-label Extension of the ORIGIN Study – Explore the Visual Abstract
This visual abstract was supported by Vera Therapeutics. Download Visual Abstract
Celebrating Excellence: Meet Eleven New ISN-Named Fellows
The ISN congratulates its newest ISN-Named Fellows: Megan Borkum and Neeru Agarwal for ISN-ACT (clinical trials) Rajitha A. Abeysekera for SharE-RR (registries) Somkanya Tungsanga, Nivedita Kamath, Victoria Nkunu, Caner Alparslan, Viviane Calice-Silva, Abduzhappar Gaipov, Anna Francis and Maria Pippias, for ISN-GKHA (ISN-Global Kidney Health Atlas) Learn more about our ISN-Named Fellows here These early-career ISN members were approved as ISN-Named...
Results From ISN’s Kidney Care Network Published in PLOS Medicine: Advancing Acute Kidney Disease Management in Low-resource Settings
Download PDF A groundbreaking study led by ISN members as part of the Kidney Care Network (KCN) initiative has been published in PLOS Medicine. This research provides critical insights into acute kidney disease (AKD) in low- and lower-middle-income countries (LLMICs) and proposes actionable solutions to address gaps in care. Read the publication here Why this study matters AKD...
New Perspectives on Treatment Protocols: Kidney International® Publishes Late-breaking Clinical Trials
Two significant research studies were accepted as late-breaking clinical trials at Kidney Week 2024 and have subsequently been published in Kidney International®. Higher Intraoperative Blood Pressure Does Not Reduce Acute Kidney Injury in Non-Cardiac Surgery: What Do the Results of the POISE-3 Trial Tell Us? The POISE-3 trial's analysis found no benefit in targeting a...