Journals

KI publishes ISN’s International Consensus Definitions of Clinical Trial Outcomes for Kidney Failure: 2020

Kidney International has published the International Consensus Definitions of Clinical Trial Outcomes for Kidney Failure: 2020, developed from the 1st International Consensus Meeting on Defining Kidney Failure in Clinical Trials hosted by the ISN in Vancouver, BC, Canada, in early 2020. Kidney failure is an important outcome for patients, clinicians, researchers, healthcare systems, payers, and regulators. However,...

International Perspectives on Patient Involvement in Clinical Trials in Nephrology

The involvement of patients in nephrology clinical trials is limited despite their ability to prioritize research, help with study design, participation, and implementation of results. The aim of this position paper is to review the need for and challenges of patient involvement; to assess the present situation of patient involvement; and to describe the...

Functional Assessment of Fatigue and Other Patient-Reported Outcomes in Patients Enrolled in the Global aHUS Registry

This longitudinal studyassessedfatigue and treatment status in patients with Atypical hemolytic uremic syndrome (aHUS) from the Global aHUS Registry. The results confirm the detrimental effects of aHUS on patients’ daily lives, especially in terms of fatigue,butdemonstratessignificant improvement in symptoms following treatment with eculizumab.

A Planetary Health Perspective for Kidney Disease

In response to factors such as climate change, unsustainable kidney-treatment methods, and CKD epidemics due to toxins and extreme working conditions, the authors urge nephrologists to pay particular attention to the effects of global warming and its potential to cause acute and chronic kidney injury, severe dehydration, and electrolyte disturbances. The authors propose a “planetary health” approach...

Young ISN Members Reflect on Working Conditions During the COVID-19 Pandemic

Young ISN members continue to work on the frontline of the COVID-19 pandemic. Rhys Evans, a member of the ISN Young Nephrologists Committee, asked young ISN members from India, Ecuador, and Nigeria, to reflect on their experiences. Read reflections from other young ISN members here. Find resources relating to the COVID-19 infection here. Reflections from Chandigarh, India Joyita Bharati, Assistant...

How Is COVID-19 Affecting You? ISN Members Reply

As COVID-19 continues to have a global impact, the ISN reached out to its members around the world to hear about the crisis in their own words. Below are some first-hand accounts. What has your experience been so far? ISN members are encouraged to tell us on Twitter or Facebook using #ThisIsISN and have your testimonial added here. “During the quarantine period, my life...

KDIGO Report to be published in Kidney International and Kidney International Reports

KDIGO’s Nomenclature for Kidney Function and Disease Conference Report and Glossary will be released in the June issue of Kidney International. An executive summary and glossary will be published in KI Reports. The KDIGO consensus conference took place in June 2019 providing a platform to discuss standardizing and refining kidney-related terminology to be more patient-centered and precise and to...

Announcing the ISN Global Kidney Care Podcast

The ISN Global Kidney Care Podcast (GKCP) , to be launched this month, will initially focus on the COVID-19 pandemic. Over time, the GKCP will provide content on science, research, and clinical aspects of nephrology, including: Case-Based Discussions Paradox Nephrology Everyday Nephrologists Latest Kidney International and Kidney International Reports Papers The GKCP will be available via numerous podcast platforms and apps, including Apple, Stitcher, Spotify,...

ISN-H4KH Research Abstracts Published in Kidney International Reports

In 2018, Sandra Wagner (France), Angie Aguilar-Gonzalez (Guatemala), and Amarasiri de Silva (Sri Lanka/USA) received ISN-H4KH (Hydration for Kidney Health) Grants for their respective projects. All three recipients had their abstracts accepted for presentation at WCN’20 and, consequently, published in Kidney International Reports. Sandra Wagner et al. investigated the association between Uosm and eGFR decline; and the...

ISN President, Vivek Jha, takes the lead on the “Novel Coronavirus 2019 Epidemic and Kidneys”

Novel coronavirus disease (COVID-19) is a newly discovered contagious disease caused by SARS-CoV-2 virus, primarily manifesting as an acute respiratory illness with interstitial and alveolar pneumonia, but can affect multiple organs such as kidney, heart, digestive tract, blood and nervous system. The rapidly spreading outbreak which first emerged in Wuhan, Hubei Province in China...

Milestones in Nephrology: Treatment of Glomerular Diseases – Pioneering Clinical Trials

Celebrating ISN’s 60th anniversary, Kidney International’s “Milestones in Nephrology” series continues with a review of some of the original articles it has published on the treatment of glomerular disease, publications that helped make significant changes in patient management: Shorter term corticosteroids are equally effective as longer term in primary nephrotic syndrome in children (Yoshikawa N, Nakanishi K, Sako...

Milestones in Nephrology: Systemic autoimmune diseases and the kidney

To celebrate ISNs 60th anniversary, Kidney International’s “Milestones in Nephrology” series continues with a review of some of the original articles it has published on the effects of systemic autoimmune diseases on the kidney. These articles have characterized the pathology and clinical course of these diseases and enabled the nephrology community to make informed decisions in...

Pathophysiology of the glomerulus: KI tells the story

To celebrate ISN’s 60th anniversary throughout 2020, Kidney International’s “Milestones in Nephrology” series launches with a review of the development in understanding of the pathophysiology of the glomerulus, highlighting several original articles published in KI: The glomerular signature in patients with hematuria (Kenneth F. Fairley and Douglas F. Birch, 1982); The permselectivity of the glomerular capillary wall (Ramsay L.S....

August in KI: Take time out for reading

The editors of Kidney International (KI) would like to share a selection of articles from the August edition of the publication. Articles focus on a broad range of topics from renal pathology practice globally, the genomic landscape of CAKUT, identifying geospatial “hotspots” of glomerular diseases, the disease-specific incident glomerulonephritis displays geographic clustering in under-serviced rural areas of...

ISN-ACT Global Trials Focus: CKD, dialysis and hypertension

This month, the first series of clinical trials curated by the ISN-Advancing Clinical Trials (ISN-ACT) team will get us thinking about nephrology research and encourage more discussion about chronic kidney disease, dialysis and hypertension: from PD catheter exit site care, the effectiveness of Roxadustat, to the initial treatment of hypertension in Sub-Saharan Africans and...

June in KI: Take time out for reading

This month, we have lots of new educational material for you to delve into. From new in-depth reviews in Kidney International (KI) to June's KI editor’s picks.  Big science and big data in nephrology Over the next few months, Kidney International (KI) will feature in-depth reviews on big science, artificial intelligence, and machine learning. This review, the first in this series, provides...