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Kidney International® Pegcetacoplan prophylaxis for recurrent C3 glomerulopathy with multifactorial genetic background C3 glomerulopathy (C3G) has a high risk of recurrence after kidney transplantation, and there is limited evidence on how best to prevent it. This case report describes a child with severe, early-onset C3G and a complex genetic background who received pegcetacoplan before and after a living-donor kidney transplant as prophylaxis...