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ISN Journal Editorial Selections

Kidney International®

Novel Anemia Therapies in CKD: Conclusions from a KDIGO Controversies Conference 

The conference, held virtually in December 2021, reviewed new evidence on diagnosing and managing anemia in chronic kidney disease (CKD). The meeting focused on a new class of agents—the hypoxia-inducible factor-prolyl hydroxylase inhibitors (HIF-PHIs).

HIF-PHIs are reported to be non-inferior to conventional Erythropoiesis-Stimulating Agents in managing hemoglobin levels and reducing transfusion needs in both non-dialysis and dialysis CKD patients.

However, concerns about cardiovascular safety persist, and there is no conclusive evidence supporting a reduction in the need for iron supplementation or improved anemia correction in states of chronic inflammation with HIF-PHIs.


Kidney International Reports®

The Role of Nephrology Nurses in Symptom Management – Reflections on the Kidney Diseases: Improving Global Outcomes Controversies Conference on Symptom-based Complications in Dialysis Care

The conference, held in May 2022, tackled the challenge of dealing with symptoms in dialysis patients. They discussed ways to:

  • Incorporate symptom assessment into routine care
  • Ease physical symptoms
  • Improve the management of psychological symptoms
  • Find system-level approaches for better symptom management.

The conference outcomes show that healthcare experts in kidney health are committed to making sure symptoms are assessed and managed in a personalized way and become part of routine clinical care.


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