News

Cardiovascular disease, chronic kidney disease, diabetes, and obesity are closely interconnected, yet care is often delivered through separate clinical pathways.

In October 2025, the ISN convened the ISN International Expert Forum, “Exploring the Nexus of Cardiovascular-Kidney-Metabolic (CKM) Health,” to examine how a more integrated CKM approach could improve prevention, treatment, and care delivery. The resulting meeting report has now been published in Kidney International®. 

Read the meeting report in Kidney International® 

A global, multidisciplinary group of experts examined CKM risk stratification, lifestyle interventions, guideline-directed therapies, emerging treatments, and models of care. 

Participants emphasized the need for earlier case finding, combined kidney and cardiovascular risk assessment over time, and timely use of evidence-informed therapies to reduce kidney disease progression, kidney failure, and cardiovascular events. 

The report also highlights persistent barriers, including therapeutic inertia, fragmented care, and inequities in access, while pointing to multidisciplinary and system-level models that could help translate evidence into practice more effectively. 

Explore the ISN CKM initiative for resources and tools supporting a shared approach to cardiovascular-kidney-metabolic health across disciplines and regions.