Kidney disease means your kidneys are damaged and can’t filter blood the way they should. Those with diabetes or high blood pressure are at greater risk of developing kidney disease.
Kidney problems include acute kidney injury, chronic kidney disease, kidney cysts, kidney stones, and kidney infections.
Kidney International® Conventional cytotoxic chemotherapy–associated nephrotoxicity: consensus report of the 34th Acute Disease Quality Initiative (ADQI) Workgroup Conventional cytotoxic chemotherapy remains essential in cancer care, but can cause acute and chronic kidney injury. The 34th ADQI Workgroup reviewed the epidemiology, mechanisms, risk factors, clinical manifestations, prevention, and management of nephrotoxicity linked to commonly used agents. The resulting consensus report emphasizes clinician awareness,...
Reconnect with the resources, opportunities, and community that support your professional growth and help advance kidney health worldwide. For a limited time, ISN membership is available at 50% off for the remainder of 2026 with code 50ISN26. Join the ISN or renew your membership at 50% off Join or renew today to gain access to thousands of hours of educational content,...
As you continue to use ISN-Global Kidney Health Atlas (ISN-GKHA) data in your work or look to better understand the global kidney health landscape, listen to an ISN Roundtable marking the ISN-GKHA’s 10th anniversary that offers valuable insights into one of the nephrology community’s most influential resources. Access the ISN-GKHA 2027: 10-Year Round-Up Roundtable video In the discussion, leaders behind the ISN-GKHA reflect on the atlas’ evolution and its worldwide impact. David Johnson...
“If a drug improves creatinine but makes a patient too fatigued to work, that’s a safety signal we might be missing.” How can nephrology translate recent advances in research into better outcomes for people with kidney diseases? In the second episode of the ISN PARADIGM in Clinical Trials podcast series, drawing on insights from the Consensus Meeting on Changing Paradigms...
“We are truly a global journal: We do not just select [from] one area that has resources ... authors can submit their papers from whatever region they’re from.” Jai Radhakrishnan As Kidney International Reports® (KIR) marks its 10th anniversary, a WCN'26 Kidney Studio interview with Editor-in-Chief Jai Radhakrishnan reflects on how a bold early commitment to open access and a dedication to...
A new case report in Kidney International Case Reports™ (KICR) describes an exceptionally rare delayed dual invasive fungal infection involving mucormycosis and aspergillosis in the native kidney of a kidney transplant recipient more than 10 years after transplantation. Macroscopic appearance of small whitish tissue (fungal ball) passed in urine The patient presented with fever, right loin...
“By connecting policy, primary care, and health financing, we can help translate global commitments [for kidney health] into practical action and support progress in the lead-up to the 2027 UN High-Level Meeting on UHC.” Marcello Tonelli, co-author of the paper A new health policy paper published in The Lancet, led by ISN President Marcello Tonelli along with an international group of experts, sets out a step-by-step framework to help...
Concerned about the environmental impact of kidney care but unsure where to start? The ISN Green Nephrology Toolkit offers practical guidance to help healthcare professionals introduce simple, sustainable changes within their kidney care units. Explore the toolkit Developed in collaboration with the ISN Emerging Leaders Program cohort 2 with support from the GREEN-K* steering committee, the toolkit is designed for teams at any stage of their sustainability...
What do kidney care priorities look like across ISN regions? In a series of WCN'26 Kidney Studio interviews, several ISN regional board chairs and deputy chairs share perspectives on the challenges and opportunities shaping kidney care in their regions. The interviews show how regional leadership connects the ISN's global mission with local realities, from earlier diagnosis and workforce development to access, education, and awareness. Oceania and South East Asia: Expanding access and...
Kidney International® A population-based,regression discontinuity analysis examined the effects of nationwide alerting for acute kidney injury on health care and patient outcomes This study assessed whether Wales’ nationwide electronic alerts for acute kidney injury (AKI) improved care or patient outcomes in real-world practice. Using a population-based regression discontinuity analysis of hospital and community data from 2016 to...
This June, the ISN will contribute to nephrology events in Korea and Italy, supporting opportunities for kidney care professionals to exchange knowledge, build connections, and share expertise. 46th Annual Meeting of the Korean Society of Nephrology (KSN 2026) Shaping Tomorrow’s Nephrology: Insight-Driven Kidney Care June 11-14, 2026 Seoul, Korea Visit us at our booth and join the KSN-ISN...
Pregnancy-associated acute kidney injury (PrAKI) remains a major contributor to maternal and perinatal morbidity worldwide, yet its true global burden has never been captured in a single, coordinated dataset. Developed with ISN support, the first PrAKI Global Snapshot will help address this gap through an international, non-interventional service evaluation using anonymized, routinely collected clinical data. Building on the existing partnership between...
Why does chronic kidney disease of unknown origin (CKDu) remain so difficult to define, study, and prevent? In this episode, experts from the ISN i3C Working Group unpack the research gaps that continue to slow progress and discuss what is needed to move the field forward. Ben Caplin, Magdalena Madero, Eranga Wijewickrama, and Shuchi Anand* highlight gaps...
As part of its broader engagement during the World Health Assembly (WHA79) in Geneva from May 18 to 23, 2026, the ISN will contribute to two side events on May 20, including an important milestone: the first official WHA side event for which the society was invited to submit a proposal. Taking place just days before the first anniversary of the WHO kidney health resolution's approval, discussions at WHA79 will build on...
Can lower-exposure tacrolimus plus everolimus improve outcomes in older kidney transplant recipients? Could high-dose omega-3 supplementation offer a simple way to reduce cardiovascular risk in dialysis? Might a more conservative dialysis strategy actually help support kidney recovery? Available in English and Russian, the ISN TrialWatch Special Edition offers a curated look at selected randomized kidney care trials from 2025 and early 2026. Explore...
Kidney International® A secondary analysis of the TESTING trial predicted individual patient response to corticosteroid treatment in IgA nephropathy This study addressed how to better target corticosteroid treatment in IgA nephropathy, (IgAN) where benefits must be weighed against important side effects. Using a secondary analysis of the TESTING trial, the authors developed a model to predict each patient’s likely response to...
What if better research approaches could help take the “unknown” out of chronic kidney disease of unknown etiology (CKDu)? Launched at WCN’26, the new ISN i3C CKDu Toolkit* is designed to help build research capacity in CKDu-endemic regions by strengthening study design and implementation through consistent approaches to case definitions, exposure assessment, and outcome measurement. Explore the ISN i3C Toolkit It offers practical guidance to strengthen the rigor,...
From unmet needs in immune-mediated kidney diseases to therapeutic advances in C3G, WCN’26 Industry Sessions explored some of the most pressing topics in global kidney care today. Session recordings are open access and available on demand at the ISN Academy. Explore all industry symposia at the ISN Academy Discover dozens of sessions offering fresh perspectives on emerging science and new developments to help you stay up to date...
Ten years ago, Kidney International Reports® (KIR) launched with a clear mission: to expand access to high-quality kidney research and ensure that important discoveries reach clinicians, researchers, and health systems worldwide. Over the past decade, the journal has published studies that have shaped care and policy, fostered opportunities for early-career researchers to contribute and collaborate, and elevated voices...
As kidney care moves toward earlier molecular diagnosis and more precise treatment strategies, genomic insights are becoming increasingly relevant to everyday practice. Reflecting this shift, the newest ISN Academy Genetics Curriculum modules focus on topics ranging from congenital anomalies of the kidney and urinary tract to apolipoprotein L1 nephropathy. Explore the ISN Genetics Curriculum The curriculum also features five...
