Kidney disease means your kidneys are damaged and can’t filter blood the way they should. Those with diabetes or high blood pressure are at greater risk of developing kidney disease.
Kidney problems include acute kidney injury, chronic kidney disease, kidney cysts, kidney stones, and kidney infections.
Kidney International® A population-based,regression discontinuity analysis examined the effects of nationwide alerting for acute kidney injury on health care and patient outcomes This study assessed whether Wales’ nationwide electronic alerts for acute kidney injury (AKI) improved care or patient outcomes in real-world practice. Using a population-based regression discontinuity analysis of hospital and community data from 2016 to...
This June, the ISN will contribute to nephrology events in Korea and Italy, supporting opportunities for kidney care professionals to exchange knowledge, build connections, and share expertise. 46th Annual Meeting of the Korean Society of Nephrology (KSN 2026) Shaping Tomorrow’s Nephrology: Insight-Driven Kidney Care June 11-14, 2026 Seoul, Korea Visit us at our booth and join the KSN-ISN...
Pregnancy-associated acute kidney injury (PrAKI) remains a major contributor to maternal and perinatal morbidity worldwide, yet its true global burden has never been captured in a single, coordinated dataset. Developed with ISN support, the first PrAKI Global Snapshot will help address this gap through an international, non-interventional service evaluation using anonymized, routinely collected clinical data. Building on the existing partnership between...
Why does chronic kidney disease of unknown origin (CKDu) remain so difficult to define, study, and prevent? In this episode, experts from the ISN i3C Working Group unpack the research gaps that continue to slow progress and discuss what is needed to move the field forward. Ben Caplin, Magdalena Madero, Eranga Wijewickrama, and Shuchi Anand* highlight gaps...
As part of its broader engagement during the World Health Assembly (WHA79) in Geneva from May 18 to 23, 2026, the ISN will contribute to two side events on May 20, including an important milestone: the first official WHA side event for which the society was invited to submit a proposal. Taking place just days before the first anniversary of the WHO kidney health resolution's approval, discussions at WHA79 will build on...
Can lower-exposure tacrolimus plus everolimus improve outcomes in older kidney transplant recipients? Could high-dose omega-3 supplementation offer a simple way to reduce cardiovascular risk in dialysis? Might a more conservative dialysis strategy actually help support kidney recovery? Available in English and Russian, the ISN TrialWatch Special Edition offers a curated look at selected randomized kidney care trials from 2025 and early 2026. Explore...
Kidney International® A secondary analysis of the TESTING trial predicted individual patient response to corticosteroid treatment in IgA nephropathy This study addressed how to better target corticosteroid treatment in IgA nephropathy, (IgAN) where benefits must be weighed against important side effects. Using a secondary analysis of the TESTING trial, the authors developed a model to predict each patient’s likely response to...
What if better research approaches could help take the “unknown” out of chronic kidney disease of unknown etiology (CKDu)? Launched at WCN’26, the new ISN i3C CKDu Toolkit* is designed to help build research capacity in CKDu-endemic regions by strengthening study design and implementation through consistent approaches to case definitions, exposure assessment, and outcome measurement. Explore the ISN i3C Toolkit It offers practical guidance to strengthen the rigor,...
From unmet needs in immune-mediated kidney diseases to therapeutic advances in C3G, WCN’26 Industry Sessions explored some of the most pressing topics in global kidney care today. Session recordings are open access and available on demand at the ISN Academy. Explore all industry symposia at the ISN Academy Discover dozens of sessions offering fresh perspectives on emerging science and new developments to help you stay up to date...
Ten years ago, Kidney International Reports® (KIR) launched with a clear mission: to expand access to high-quality kidney research and ensure that important discoveries reach clinicians, researchers, and health systems worldwide. Over the past decade, the journal has published studies that have shaped care and policy, fostered opportunities for early-career researchers to contribute and collaborate, and elevated voices...
As kidney care moves toward earlier molecular diagnosis and more precise treatment strategies, genomic insights are becoming increasingly relevant to everyday practice. Reflecting this shift, the newest ISN Academy Genetics Curriculum modules focus on topics ranging from congenital anomalies of the kidney and urinary tract to apolipoprotein L1 nephropathy. Explore the ISN Genetics Curriculum The curriculum also features five...
The 44th Vicenza Course AKI-CRRT-EBPT and Critical Care Nephrology 2026 will take place from June 16-18, 2026, at the Vicenza International Convention Centre in Vicenza, Italy. This hands-on course for beginner and advanced kidney care professionals explores the latest advances in acute kidney injury, from diagnosis and treatment strategies to emerging therapies to help prevent progression to chronic kidney disease. Explore the preliminary scientific...
The ISN “Are your kidneys healthy?” quiz webpage has been refreshed with a new design that makes key kidney health information easier to explore. Access the “Are your kidneys healthy?” quiz Available in 35 languages, the quiz helps better understand kidney function, risk factors, and steps they can take to protect their kidney health. Share the quiz with your patients to open a dialogue about...
The winning film* of the ISN Community Film Event, “Aurenis Choir: A Song of Hope” is a moving story from Argentina that reminds us that kidney care is not only about medicine, but also about connection, creativity, and hope. The Aurenis Choir was founded on World Kidney Day 2024 with the aim of creating a space for community, art, and meaning alongside...
Kidney International® Modern challenges in infection prevention: encapsulated organisms in the era of novel complement inhibitors This mini review examines infection prevention in patients receiving novel complement inhibitors, with a focus on serious infections caused by encapsulated organisms. It outlines practical strategies, including vaccination, antibiotic prophylaxis, and patient education. The authors stress that these therapies offer important benefits...
The ISN’s new IgA Nephropathy Curriculum delivers timely, practice-focused insights to help you integrate emerging evidence into care and optimize outcomes. Access the curriculum at the ISN Academy The curriculum is organized into three core areas of IgAN: pathogenesis, treatment, and prediction. Each section features in-depth conversations with David Wheeler, Jonathan Barret, and Michelle O'Shaughnessy, conducted...
The ISN-led GREEN-K* (Global Environmental Evolution in Nephrology and Kidney Care) initiative invites the global kidney community to review and comment on a joint draft statement, “Procurement for Environmentally and Ethically Sound Kidney Care Products and Services.” Read the draft statement and share your feedback by...
Kidney International® A single-arm phase 2 trial of an investigational RNA therapeutic targeting complement factor B (sefaxersen) for treatment of IgA nephropathy IgA nephropathy (IgAN) involves activation of the complement alternative pathway, contributing to kidney inflammation and disease progression. In this global, open-label phase 2 trial, patients with biopsy-confirmed IgAN received sefaxersen, an antisense inhibitor of complement factor B, to...
In Japan, the art of kintsugi repairs broken pottery with adhesive and powdered gold, transforming fracture into renewed strength. As the global kidney care community prepares to gather in Yokohama for WCN’26, Japan’s approach to kidney health offers a compelling parallel: working with impairment to preserve function, extending quality of life in an aging society, and continuously strengthening systems of care through early detection and...
Looking to strengthen your confidence in diagnosing and managing glomerular diseases? The ISN Primer Course in Glomerular Diseases offers an intensive, case-based learning experience designed to sharpen clinical decision-making and connect you with international faculty and peers. Applications are now open for the next edition of the course in Montevideo, Uruguay, from August 8–9, 2026. Find...
