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ISN International Consortium CKDu Collaborators (ISN i3C) Network Meeting Affirms Need to Build Capacity for Kidney Biopsies in CKDu Within Ethical Framework

Held in May, the meeting brought together 40 members of the ISN i3C (International Consortium CKDu Collaborators) network and the ISN Renal Pathology Working Group

The meeting highlighted the need to increase kidney biopsies in CKDu (chronic kidney disease of unknown origin) and improve biopsy preservation. 

Three ISN i3C network members presented: Richard Johnson outlined the usefulness of kidney biopsies in the study of CKDu, followed by a presentation from Chulani Herath on the ethics of performing kidney biopsies in patients with CKD (Chronic Kidney Disease). Karen Courville shared data on kidney biopsies in regions with a high prevalence of CKDu. 

Shuchi Anand, ISN iC3 Working Group chair, and meeting moderator alongside ISN iC3 Working Group deputy chair Eranga Wijewickrama, presented the concluding words, emphasizing the importance of working within an ethical framework and confirming the ISN i3C network’s plans to develop a strategy toward action. 

Commenting on the success and potential impact of the meeting, Surya Seshan, ISN Renal Pathology Working Group member, says, “It is admirable that although the etiology and pathophysiologic mechanisms may be diverse in various parts of the world, the ISN is addressing this issue in a global manner. It was a great session.”

Karen Courville continues, “It was very interesting to share the different viewpoints from nephropathologists and clinicians because it is a pathology that continues without a specific cause and many limitations to performing early biopsies exist, especially because patients present at a late stage.”





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