Journals

Five compelling reasons to submit to Kidney International Case Reports™  

Case reports are often where progress begins. A single patient, an unexpected presentation, a practical clinical lesson that sharpens judgment and sparks discussion, ultimately leading to improved understanding and care.   With the recent launch of the ISN’s new fully open-access journal, Kidney International Case Reports™ (KICR)*, there has never been a better time to share bedside observations with the global kidney care community.  Submit a...

ISN Journal summaries on sodium-glucose cotransporter-2 inhibitors and CKD in indigenous populations in Kerala 

Kidney International®   Strategies for the development of sodium-glucose cotransporter-2 inhibitors for kidney protection in pediatric chronic kidney disease: proceedings of a workshop meeting in July 2023 There are currently no approved therapies to slow chronic kidney disease (CKD) progression across the diverse causes of pediatric CKD, despite evidence that sodium–glucose cotransporter-2 inhibitors (SGLT2is) slow kidney disease...

Bridging global kidney care gaps through data: KI presents ISN-GKHA Interactive Map   

A recent Kidney International® editorial showcases the ISN-Global Kidney Health Atlas (ISN-GKHA) Interactive Map, an open-access tool that enables clinicians, researchers, policymakers, and advocates to identify gaps and target areas where kidney care improvements are most needed.  Read the full paper in Kidney International®  Consolidating data from the 2019 and 2023 ISN-GKHA surveys, the map:  Compares kidney care capacity between countries and regions  Tracks trends and measures progress over time  Visualizes key indicators like workforce, infrastructure, and policies  Provides evidence to guide research, advocacy, and policy initiatives  Explore...

ISN Journal summaries on anemia in CKD and urine dipstick testing 

Kidney International®   Executive summary of the KDIGO 2026 Clinical Practice Guideline for the Management of Anemia in Chronic Kidney Disease (CKD)  The KDIGO 2026 guideline updates the management of anemia in CKD in light of new evidence and emerging therapies since the 2012 update.  It provides evidence-based recommendations on diagnosis and treatment, including iron therapy, erythropoiesis-stimulating agents, hypoxia-inducible factor–prolyl hydroxylase inhibitors,...

“An important role disseminating kidney science across the globe”: Celebrating 10 years of Kidney International Reports®

Visual featured in the KIR editorial on its 10th anniversary To mark 10 years of the ISN Journal Kidney International Reports® (KIR), we spoke with Editor-in-Chief Jai Radhakrishnan and Deputy Editor Sumit Mohan about the journal’s origins, defining moments, and how its mission has evolved over the past decade. Explore all ISN Journals Creating a home for...

Bedside insights to advance kidney care: Submissions open for new article type in Kidney International® 

Kidney International® (KI) introduces a new article type — “Clinical Journey in Translational Medicine” — spotlighting patient cases that link bedside observations to underlying mechanisms of disease.   Submissions are now open  This concise feature bridges clinical nephrology and discovery science, revealing how individual cases can advance understanding of pathophysiology, diagnostics, or treatment.   “The patient’s journey is ultimately what it’s all about. “Clinical Journey in...

From implementing global kidney health commitments to results of the Phase 2 ACTION2 trial: Read the latest ISN Journal summaries  

Kidney International®   Implementing the commitments of the WHO Kidney Health Resolution: Initial steps in three diverse settings  Chronic kidney disease (CKD) affects 850 million people globally, with the highest burden in low- and middle-income countries. The WHA78 kidney health resolution offers a unique opportunity to advance prevention and care.   This editorial presents case studies from Guatemala, Thailand,...

The ISN launches Kidney International Case Reports: Shaping clinical practice in global kidney care through real-world insights

December 1, 2025 The International Society of Nephrology (ISN) is proud to announce the launch of Kidney International Case Reports (KICR), a new peer-reviewed, open-access journal dedicated to publishing high-quality case reports, focused reviews, and short clinical communications relevant to kidney care. An official ISN Journal, KICR joins Kidney International®, Kidney International Reports®, and Kidney International...

ISN Journal summaries on APOL1 kidney disease and expanding peritoneal dialysis in India 

Kidney International®   APOL1 kidney disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference  APOL1 genetic variants increase the risk of progressive chronic kidney disease among people of African ancestry. A 2024 KDIGO Controversies Conference reviewed current evidence and debated terminology, testing, and management approaches.   Participants agreed on using the term “APOL1 kidney disease,” but found...

Kidney International® publishes new CKD remission paradigm, presented simultaneously at Kidney Week 2025

Kidney International® (KI) published "From progression to remission: a new paradigm for success in chronic kidney disease," by Nav Tangri, David Cherney, Katherine Tuttle, and Vlado Perkovic. The article was released at the same time as its presentation at ASN Kidney Week, increasing the study's visibility and reinforcing its significance to the global kidney community.  Read the article in KI  The research emphasizes a shift in...

ISN Journal summaries on kidney transplantation in patients with plasma cell dyscrasia and gender differences in living kidney donation 

Kidney International®   Management recommendations for kidney transplantation in patients with plasma cell dyscrasia  Patients with plasma cell dyscrasia such as multiple myeloma and AL amyloidosis often develop kidney failure but have been underrepresented in kidney transplantation due to recurrence risk and poor outcomes. A multidisciplinary panel reviewed new evidence showing improved survival with modern therapies and expanding transplant eligibility....

ISN Emerging Leaders spotlight the role of non-physician health workers in kidney care 

Kidney International Reports® has published a paper from the ISN Emerging Leaders Program (ELP) Cohort 3, “Expanding kidney care: How non-physician health workers can address the global CKD crisis.”   The publication explores how non-physician health workers — such as community health workers and nurses — can help close critical gaps in chronic kidney disease prevention...

ISN Journal summaries on felzartamab for IgA nephropathy and a new anti-podocin ELISA  

Kidney International®   Randomized, double-blind, placebo-controlled phase 2a study assessing the efficacy and safety of felzartamab for IgA nephropathy  A phase 2a trial tested felzartamab, an anti-CD38 antibody, in 54 patients with IgA nephropathy. Patients received different doses of felzartamab or placebo over six months.   Felzartamab reduced protein in the urine, with the strongest and longest-lasting effect seen...

ISN Journal summaries on the DIALIZE-Outcomes trial and heat stress nephropathy in CKDu hotspots in India 

Kidney International®   The randomized DIALIZE-Outcomes trial evaluated sodium zirconium cyclosilicate in hemodialysis  People on hemodialysis often face dangerous swings in blood potassium that can trigger sudden death or heart rhythm problems.   The DIALIZE-Outcomes trial tested whether the potassium binder sodium zirconium cyclosilicate (SZC) could reduce serious cardiovascular events compared with placebo in 2,690 patients with kidney failure.  The...

ISN Journal summaries on the KDIGO Guideline on IgAN and IgAV, and urinary dickkopf-3 to predict GFR loss 

Kidney International®   KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV)  IgA nephropathy and IgA vasculitis are leading causes of kidney disease worldwide, but treatment approaches have long varied.   The KDIGO 2025 guideline consolidates the latest evidence to provide updated recommendations on diagnosis, risk assessment, and therapies, aiming...

ISN Journal summaries on zigakibart, proteinuria, and pediatric CKD in rural Africa 

Kidney International®   Zigakibart demonstrates clinical safety and efficacy in a Phase 1/2 trial of healthy volunteers and patients with IgA nephropathy  Zigakibart, a humanized monoclonal antibody targeting A Proliferation-Inducing Ligand (APRIL), was tested in healthy volunteers and patients with IgA nephropathy (IgAN) in a Phase 1/2 trial with 100-week follow-up.   The treatment was well tolerated and led...

ISN Journal summaries on gender-specific kidney health and ethical considerations in CKDu research 

Kidney International®   Women and kidney health: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference The conference highlighted key sex- and gender-specific issues in kidney care, emphasizing chronic kidney disease’s (CKD) impact on women’s reproductive health and pregnancy outcomes.   Recommendations included counseling, multidisciplinary pregnancy management, and systematic monitoring of kidney function, blood pressure, and proteinuria.   The...

ISN Journal summaries on MGRS risk prediction and CKD screening 

Kidney International®  The Mayo MGRS Prediction Tool calculates the risk of finding monoclonal gammopathy of renal significance in a kidney biopsy in patients with monoclonal gammopathy   Determining which patients with chronic kidney disease (CKD) and monoclonal gammopathy should undergo a kidney biopsy to diagnose monoclonal gammopathy of renal significance (MGRS) remains a clinical challenge.  Researchers developed and...

ISN journal summaries on maternal preeclampsia and CKD medication safety during breastfeeding    

Kidney International®  A nationwide register-based cohort study examined the association between preeclampsia in mothers and the risk of kidney disease in their offspring  A large cohort study of over 2.2 million births has found that children born at term to mothers with preeclampsia face a higher risk of developing kidney disease later in life.  The study revealed...

ISN Journal summaries on the SONG initiative and public data in research 

Kidney International®  The Standardized Outcomes in Nephrology (SONG) initiative: A decade of harmonizing patient voices and research in kidney disease   The authors of this editorial highlight how research on chronic kidney disease has been hindered by inconsistent and often patient-irrelevant reporting of outcomes.   This challenge prompted the launch of the global Standardized Outcomes in Nephrology (SONG) initiative...