Research

Looking for guidance and best practices to start your clinical trial or to participate as a trial site?

Over 5,000 people worldwide have already visited ISN's recently launched, open-access, online resource to assist you in trial design, study conduct, data management, data analysis, and publication. More than ever, clinical trials in nephrology are needed to generate high-quality evidence to inform all aspects of care for patients with or at risk of kidney disease,...

Access the ISN Observatory of CKDu and Share Data

In collaboration with the World Health Organization (WHO), the ISN i3C (International Consortium CKDu Collaborators) group has developed the ISN Observatory of CKDu to facilitate the exchange of information and knowledge to raise awareness of the urgent issue of Chronic Kidney Disease of unknown etiology. The input of experts in the field of CKDu provides both the ISN...

ISN to Launch Observatory Map on CKDu on May 7

As part of its Collaboration Plan with the World Health Organization (WHO), the ISN i3C (International Consortium CKDu Collaborators) group has developed a CKDu Observatory Map to facilitate the exchange of information and knowledge in order to raise awareness of the urgent issue of Chronic Kidney Disease of unknown etiology. Be the first to access...

Access and Present Region-specific Slides based on the ISN Global Kidney Health Atlas (GKHA) 2019

The ISN Global Kidney Health Atlas team has prepared summary slides of the ISN GKHA 2019 focusing on each ISN region individually. ISN invites members to share the results from their region with colleagues and key stakeholders to support discussions on and advocate for kidney health care with relevant national and regional health/policy/education officials. The new material contains...

Global Trials

Every month the ISN-ACT Team lists interesting new randomized controlled trials from around the world. Highlights: Keeping it simple with restriction: fluid restriction as good as diuretics and oral salt for SIAD Deciding HDF or HD: nothing to lose sleep over See the latest trials here.

ISN-H4KH Grant Awardee Publishes Research Findings

“High water intake and low urine osmolality are associated with favorable metabolic profile at a population level: low vasopressin secretion as a possible explanation” by ISN Hydration For Kidney Health (ISN-H4KH) Research Grant awardee, Sofia Enhörning, was published in the European Journal of Nutrition in February. Sofia Enhörning et al, investigated if low total water intake or high...

World Kidney Day 2020: The onset and progression of CKD are often preventable

Prof. Philip KT Li Honorary Professor of Medicine, Chinese University of Hong Kong and President of Hong Kong College of Physicians, and represents ISN on the WKD Joint Steering Committee   Dr. Guillermo García García Research Professor, University of Guadalajara Health Sciences Center, and Director of Nephrology, Hospital Civil de Guadalajara, Mexico, and represents IFKF on the WKD...

Lillian Jean Kaplan International Prize to be Awarded Annually

The Lilian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease (PKD) will now be awarded annually. ISN is grateful to Thomas Kaplan and the Recanati-Kaplan Foundation for their generosity in making this possible. The Lillian Jean Kaplan Prize recognizes individuals exhibiting excellence and leadership in PKD clinical or basic research that improves...

KI Supplements publishes papers on increasing access to integrated ESKD care worldwide

Kidney International Supplements (KIS) has published a set of papers describing the background, rationale, and action plans for developing a strategic approach to increase access to integrated end-stage kidney disease (ESKD) care worldwide over the next decade. Read this special edition here. Following March 2018's second Global Kidney Health Summit organised by the International Society of Nephrology (ISN), the primary...

Don’t miss the launch of the ISN Advancing Clinical Trials Toolkit at WCN20

The ISN Advancing Clinical Trials Toolkit is designed to assist in carrying out meaningful and robust clinical trials, or to become involved as a trial site, with the primary intention of improving patient care. Available online for the first time at the ISN World Congress of Nephrology (WCN), Congress delegates are invited to experience the...

ISN Research Collaborative Meeting and 1st International Consensus Meeting on Defining Kidney Failure in Clinical Trials

A two-day meeting was held in Vancouver, Canada, from January 31 to February 1, 2020, which brought together the ISN executive leadership, members of ISN Research groups, patients, clinicians, clinical trialists, academics, industry, and regulators to establish momentum for international collaborative work in clinical trials and research in kidney disease across the world. The meeting...

ISN Research Collaborative Meeting and 1st International Consensus Meeting on Defining Kidney Failure in Clinical Trials

A two-day meeting is to be held in Vancouver, Canada, from January 31 to February 1, 2020, bringing together members of ISN Research groups, patients, clinicians, clinical trialists, academics, industry, and regulators to establish momentum for international collaborative work in clinical trials and research in kidney disease across the world. The meeting will introduce current...

Access the latest ISN-ACT Global Trials

Every month the ISN-ACT Team lists interesting new randomized controlled trials from around the world. Highlights: Brace for it: an external support device may help fistulas to mature Getting things straight when it comes to peritoneal dialysis catheters See the latest trials here

Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

A multidisciplinary group of researchers and clinicians met in October 2018 to identify evidence and address controversies in potassium management providing research priorities and guidance for evaluation and management of dyskalemias in the context of kidney diseases.

Status of care for end stage kidney disease in countries and regions worldwide: international cross sectional survey

The ISN Global Kidney Health Atlas (GKHA) 2019 manuscript “Status of care for end stage kidney disease in countries and regions worldwide: international cross sectional survey” was published in The BMJ on October 31. The second edition of the GKHA reports on global kidney health across 160 countries representing 98% of the world’s population. The report focuses on care for end-stage kidney...

Latest ISN iNET-CKD study on hypertension now available in KI

Kidney International (KI) is pleased to announce the publication of a study on hypertension, led by the ISN iNET-CKD (International Network of chronic kidney disease cohort studies). This study highlights considerable international variation in hypertension control and treatment in chronic kidney disease (CKD). The new study from the ISN iNET-CKD highlights substantial variation in the prevalence...

August in KI: Take time out for reading

The editors of Kidney International (KI) would like to share a selection of articles from the August edition of the publication. Articles focus on a broad range of topics from renal pathology practice globally, the genomic landscape of CAKUT, identifying geospatial “hotspots” of glomerular diseases, the disease-specific incident glomerulonephritis displays geographic clustering in under-serviced rural areas of...

ISN-ACT Global Trials Focus: Transplant, glomerular diseases and pediatric nephrology

In July 2019, the second series of clinical trials curated by the ISN Advancing Clinical Trials (ISN-ACT) team will get us thinking about nephrology research and encourage more discussion about transplant, glomerular diseases and pediatric nephrology: from the role of EPO post-transplant, tacrolimus dosing in Asian transplant recipients to the optimal duration of steroids...

Kidney Patients are Neglected in Clinical Trials

PRESS RELEASE July 9, 2019 Kidney Patients are Neglected in Clinical Trials The exclusion of patients with kidney diseases from clinical trials remains an unsolved problem that hinders optimal care of these patients. Over 850 million people suffer from kidney diseases worldwide, a number which signifies epidemic proportions, yet these patients are still ignored by investigators and...

ISN-ACT Global Trials Focus: CKD, dialysis and hypertension

This month, the first series of clinical trials curated by the ISN-Advancing Clinical Trials (ISN-ACT) team will get us thinking about nephrology research and encourage more discussion about chronic kidney disease, dialysis and hypertension: from PD catheter exit site care, the effectiveness of Roxadustat, to the initial treatment of hypertension in Sub-Saharan Africans and...