autosomal dominant polycystic kidney disease Archives - International Society of Nephrology

Explore the latest ISN Global Trials Focus selections featuring a “Trial of the month” on the effect of dapagliflozin in patients with ADPKD receiving tolvaptan

ISN-ACT Global Trials Focus editorial team member Michele Provenzano summarizes the design and outcomes of the latest "Trial of the month" featured in ISN-ACT Global Trials Focus. Trial of the month: DAPA-tolvaptan: First trial of SGLT2 inhibition in ADPKD with background tolvaptan therapy Open-label, randomized, controlled, crossover trial on the effect of dapagliflozin in patients with ADPKD receiving tolvaptan Uchiyama...

June 30, 2025News, ResearchRead more...

ISN Journal Summaries on Clinical Practice Guideline for ADPKD and Mitochondrial Function in Diabetic Kidney Disease

Kidney International® KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD): Executive Summary The KDIGO 2025 Clinical Practice Guideline for ADPKD is the first global guideline on the evaluation, management, and treatment of this genetic disorder, focusing on areas such as diagnosis, kidney manifestations, disease progression, and extrarenal...

February 3, 2025Journals, NewsRead more...

Celebrating Outstanding Contributions to Kidney Care: The 2025 ISN Awards and ISN Pioneer Award Winners

Please join us in congratulating the 2025 ISN Awards and Pioneer Award winners. ISN Awards Shilpanjali Jesudason – the Roscoe Robinson Award Marie Trudel – the Lillian Jean Kaplan Prize for polycystic kidney disease (PKD) Ariela Benigni – the Alfred Newton Richards Award ISN Pioneer Award winners Africa: Boucar Diouf (Senegal) Eastern and Central Europe: Liliana Garneata (Romania) Latin America: Ana María...

January 21, 2025Awards, News, WCNRead more...

Deciphering the Mechanisms Responsible for PKD: Announcing the Winner of the ISN 2025 Lillian Jean Kaplan Prize

Please join us in congratulating Professor Marie Trudel, the ISN 2025 Award winner for the Lillian Jean Kaplan International Prize. Professor Trudel will receive the prize during the ‘Bridging the Gap: PKD Research and Clinical Care Perspective – Kaplan PKD Session’ at the ISN World Congress of Nephrology 2025 in New Delhi, India. She will...

December 9, 2024ISN Awards, News, WCNRead more...

ISN Journal Editorial Selections on eGFR Decline and ADPKD Patient Perspectives

Kidney International® A Randomized, Open-label Clinical Trial Examined the Effects of Canagliflozin on Albuminuria and eGFR Decline Using An Individual Pre-Intervention eGFR Slope The CANPIONE study showed that canagliflozin significantly reduced albuminuria by 30.8% and slowed eGFR decline in patients with type 2 diabetes and microalbuminuria. Using a novel design comparing eGFR slopes before and during treatment,...

November 26, 2024Journals, News, ResearchRead more...

Podcast, Accredited Courses, Collaborative Case Presentations, and Open-Access Curricula: Explore Latest Releases at the ISN Academy Now!

The ISN Academy offers hundreds of hours of cutting-edge educational content developed to enhance your knowledge and skills and ensure you keep up with the latest advancements in kidney care. Brand new content includes: Latest episode of the ISN Global Kidney Care Podcast: A discussion on health disparities, their root causes, and their impact on the...

February 5, 2024Education, NewsRead more...

A Promising Alliance: The ISN and PKD Foundation Tackle Polycystic Kidney Disease

The ISN is pleased to share news of its official partnership with the Polycystic Kidney Disease Foundation, a collaboration to raise awareness about polycystic kidney disease and offer educational resources on this rare condition. Together, the two organizations will produce a webinar and podcast. Join us for the upcoming "Equity in ADPKD: Bridging Gaps for Better...

October 30, 2023Education, NewsRead more...

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