Chronic kidney disease (CKD) involves a gradual loss of kidney function. Advanced CKD can cause dangerous levels of fluid, electrolytes and waste to build up in the body as the kidneys ability to filter and eliminate excess fluids from the blood decreases.
CKD is a common condition often associated with getting older. It increases the risk of having heart and blood vessel disease. Early detection and treatment can often keep CKD from getting worse.
Kidney International® Zigakibart demonstrates clinical safety and efficacy in a Phase 1/2 trial of healthy volunteers and patients with IgA nephropathy Zigakibart, a humanized monoclonal antibody targeting A Proliferation-Inducing Ligand (APRIL), was tested in healthy volunteers and patients with IgA nephropathy (IgAN) in a Phase 1/2 trial with 100-week follow-up. The treatment was well tolerated and led...
The ISN Emerging Leaders Program (ELP) develops leadership potential to drive change in global kidney health. Since its launch, it has become a catalyst for early-career nephrologists and researchers to champion advocacy, expand research, and foster innovation in kidney care worldwide. Hurry – apply for the ISN Emerging Leaders Program by September 15! Here are some...
Faculty and delegates at the 5th Congress of the Senegalese Society of Nephrology, Dialysis, and Transplantation The ISN Continuing Medical Education (CME) Program recently supported the 5th Congress of the Senegalese Society of Nephrology, Dialysis, and Transplantation (SOSENDT) in Saly, Senegal, which gathered 332 participants from across Sub-Saharan Africa. Two ISN-supported speakers attended: Eric Goffin...
The ISN Foundation Fellowship Course* has recently been updated to better support early-career nephrologists. The course offers a solid grounding in clinical nephrology. The modules can be completed separately and include the following topics: Acute kidney injury Glomerular diseases Dialysis modalities and conservative kidney care management Chronic kidney disease Electrolytes and acid-base disorders Kidney transplantation Hosted at the ISN Academy, it...
Dr. Devarajan (wearing a suit) with the SAT Team at the National Pediatric Nephrology Conclave 2022, supported by the ISN An ISN Sister Renal Centers (SRC) collaboration between Sree Avittam Thirunal (SAT) Hospital in Kerala, India, and Cincinnati Children’s Hospital Medical Center (CCHMC), USA, has played a transformative role in developing pediatric nephrology services at...
Kidney International® The Mayo MGRS Prediction Tool calculates the risk of finding monoclonal gammopathy of renal significance in a kidney biopsy in patients with monoclonal gammopathy Determining which patients with chronic kidney disease (CKD) and monoclonal gammopathy should undergo a kidney biopsy to diagnose monoclonal gammopathy of renal significance (MGRS) remains a clinical challenge. Researchers developed and...
From global policy tools to community-driven projects and early-career development, ISN's research initiatives offer meaningful opportunities for all professionals committed to advancing kidney care. Whether you're just starting out or looking to broaden your impact, you can grow, collaborate, and drive real impact through ISN-supported research activities. We invited several contributors to share what...
The ISN invites renal pathologists, nephrologists and trainees from lower-, lower-middle-, and upper-middle-income countries to apply for an ISN Renal Pathology Bursary available for several key educational events in 2026. These bursaries aim to enhance diagnostic expertise, facilitating the early detection of kidney diseases and ultimately improving patient outcomes. Please read the guidelines carefully and submit...
A recent editorial by members of the ISN Emerging Leaders Program (ELP) cohort 3, published in Kidney International Reports®, explores urgent global disparities in chronic kidney disease (CKD) diagnostics. The piece highlights barriers to early detection—such as limited access to basic testing, biopsy services, and genetic evaluation—and proposes a tiered strategy to address these...
The ISN invites all to participate in the “KDIGO Global Survey on the Utilization and Implementation of KDIGO Guidelines.” Take the survey The survey aims to understand how KDIGO Guidelines are applied in daily practice and where challenges or gaps remain. Your insights will help tailor future guidance to better meet the needs of kidney health...
From the USA to Oceania and Southeast Asia and Latin America, ISN leaders are spotlighting global kidney health throughout July and August. Whether sharing the latest research, building partnerships, or amplifying regional voices, these engagements help elevate the global conversation on equitable kidney care. Where to find the ISN this July and August The Columbia Renal...
Kidney International® A nationwide register-based cohort study examined the association between preeclampsia in mothers and the risk of kidney disease in their offspring A large cohort study of over 2.2 million births has found that children born at term to mothers with preeclampsia face a higher risk of developing kidney disease later in life. The study revealed...
Building on a strong foundation of collaboration and training in East Africa, including the establishment of an ISN Regional Training Center in Kenya, the ISN is proud to partner on a promising new pilot project aimed at strengthening kidney care capacity in the region. The long-term vision is for this pilot to serve as...
Why do millions of people worldwide still face limited access to dialysis despite advances in kidney care? This urgent question was at the heart of the recent ISN-GKHA webinar: “Global variations in hemodialysis access and outcomes – insights for improving kidney care worldwide,” based on two extensive global studies informed by 2023 ISN-Global Kidney Health...
The ISN Pregnancy and Disease Toolkit has been expanded with three new modules to support clinicians managing complex cases in this critical area: Pregnancy-related acute kidney injury Postpartum follow-up and care Management of pregnancy hypertension and preeclampsia These evidence-based resources are ideal for personal learning or teaching others and aim to improve outcomes for mothers and babies worldwide. Access...
SEN members during a kidney care campaign We caught up with Darío Jiménez Acosta, President of the Ecuadorian Society of Nephrology (SEN), to learn how SEN is advancing kidney care locally and strengthening global ties through the ISN as a Collective-member society. Tell us about SEN and its origins SEN has been active since 1990, organizing national...
Kidney International® Identifying strategies for disseminating research to patients with chronic kidney disease and caregivers: a workshop report Research on chronic kidney disease (CKD) is often inaccessible to patients and caregivers, limiting its influence on care and decision-making. A workshop involving patients, caregivers, and health professionals identified three key strategies to improve dissemination: making research engaging and...
A new addition to the ISN-KDIGO CKD Early Identification & Intervention Toolkit offers step-by-step guidance for setting up and maintaining chronic kidney disease (CKD) early detection and intervention initiatives. Discover the new toolbox The “Starting and Sustaining Early CKD Detection and Intervention Programs Toolbox” outlines essential components for program design, from identifying at-risk populations and selecting...
Through robust data collection, international collaboration, and practical insights, the 2023 ISN-Global Kidney Health Atlas (ISN-GKHA) continues to drive progress in kidney care worldwide. This essential resource maps the availability and quality of kidney health services globally, helping kidney care professionals shape policy, support advocacy, guide research priorities, and identify service gaps, all toward...
Anisha Gerber, a pediatric nephrologist and assistant professor at the University of Virginia, became a mentee in 2023 while completing her fellowship. She was matched with Nivedita Kamath at St. John's Medical College in Bangalore, India. Apply to be a mentee by July 1 According to Anisha, the mentorship partnership has been instrumental in advancing her...
