Tag - hemodialysis

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In hemodialysis, a machine removes blood from your body, filters it through a dialyzer (artificial kidney), and returns the cleaned blood to your body. The process takes 3-5 hours in a hospital or a dialysis center three times a week.

Read the latest summaries from the ISN Journal portfolio

Kidney International®   Pegcetacoplan prophylaxis for recurrent C3 glomerulopathy with multifactorial genetic background  C3 glomerulopathy (C3G) has a high risk of recurrence after kidney transplantation, and there is limited evidence on how best to prevent it.  This case report describes a child with severe, early-onset C3G and a complex genetic background who received pegcetacoplan before and after a living-donor kidney transplant as prophylaxis...

August 31, 2026Journals, News, ResearchRead more...

Turn environmentally sustainable goals into action with the new ISN Green Nephrology Toolkit 

Concerned about the environmental impact of kidney care but unsure where to start? The ISN Green Nephrology Toolkit offers practical guidance to help healthcare professionals introduce simple, sustainable changes within their kidney care units.   Explore the toolkit   Developed in collaboration with the ISN Emerging Leaders Program cohort 2 with support from the GREEN-K* steering committee, the toolkit is designed for teams at any stage of their sustainability...

May 26, 2026Initiatives, NewsRead more...

Tune in to regional perspectives from the WCN’26 Kidney Studio 

What do kidney care priorities look like across ISN regions?  In a series of WCN'26 Kidney Studio interviews, several ISN regional board chairs and deputy chairs share perspectives on the challenges and opportunities shaping kidney care in their regions.  The interviews show how regional leadership connects the ISN's global mission with local realities, from earlier diagnosis and workforce development to access, education, and awareness.  Oceania and South East Asia: Expanding access and...

May 26, 2026News, Regional Activities, WCNRead more...

Turning shared priorities into structured, sustainable progress: CARE-NEPH in action

“With this initiative, we shall be able to train at least two nephrologists every year and create a platform for other institutions to take up the mantle."  CARE-NEPH East Africa* was launched in answer to a simple question: What becomes possible when training, institutional partnerships, and leadership development are coordinated rather than delivered separately? In East Africa, that approach is already creating new opportunities...

May 11, 2026Grants, NewsRead more...

Recent key kidney health studies in one place: Explore a special edition of ISN TrialWatch 

Can lower-exposure tacrolimus plus everolimus improve outcomes in older kidney transplant recipients? Could high-dose omega-3 supplementation offer a simple way to reduce cardiovascular risk in dialysis? Might a more conservative dialysis strategy actually help support kidney recovery?   Available in English and Russian, the ISN TrialWatch Special Edition offers a curated look at selected randomized kidney care trials from 2025 and early 2026.  Explore...

May 11, 2026News, ResearchRead more...

ISN Journal summaries on parathyroid hormone in CKD-related osteoporosis and kidney care fragility in Nepal 

Kidney International®   ​Uremia and parathyroid hormone have distinct effects on bone protein and gene expression  People with chronic kidney disease (CKD) remain at high risk of fractures despite treatment aimed at maintaining parathyroid hormone at acceptable levels.  This study examined the distinct effects of uremia and parathyroid hormone on bone in patients on hemodialysis and controls.  The authors...

April 13, 2026Journals, News, ResearchRead more...

ISN Journal summaries on the DIALIZE-Outcomes trial and heat stress nephropathy in CKDu hotspots in India 

Kidney International®   The randomized DIALIZE-Outcomes trial evaluated sodium zirconium cyclosilicate in hemodialysis  People on hemodialysis often face dangerous swings in blood potassium that can trigger sudden death or heart rhythm problems.   The DIALIZE-Outcomes trial tested whether the potassium binder sodium zirconium cyclosilicate (SZC) could reduce serious cardiovascular events compared with placebo in 2,690 patients with kidney failure.  The...

October 13, 2025Journals, News, ResearchRead more...

Training abroad, transforming at home: Four ISN Fellows lead kidney care development in Laos

Lao transplant team, including past ISN Fellows Noot Sengthavisouk (far left) and Chanmaly Keomany (far right), observing at Ramathibodi Hospital in Thailand In 2007, kidney care in Laos was limited to a few dialysis beds, with no capacity for kidney biopsy, peritoneal dialysis, or transplantation. Over the past two decades, the ISN Fellowship Program and...

September 1, 2025Fellowship, Grants, NewsRead more...

Small kidneys, big impact: Advancing pediatric kidney care in Sri Lanka 

A Sister Renal Centers (SRC) partnership has played a pivotal role in reshaping pediatric kidney care at the Lady Ridgeway Hospital (LRH) in Sri Lanka and extending its impact nationwide.  "LRH University Unit now stands as a pioneering institution in pediatric nephrology, offering outstanding clinical care and serving as a center for training and research,"...

June 30, 2025Grants, News, Sister Renal CentersRead more...

What does the ISN-GKHA tell us about global dialysis trends?  

Why do millions of people worldwide still face limited access to dialysis despite advances in kidney care?  This urgent question was at the heart of the recent ISN-GKHA webinar: “Global variations in hemodialysis access and outcomes – insights for improving kidney care worldwide,” based on two extensive global studies informed by 2023 ISN-Global Kidney Health...

June 16, 2025News, ResearchRead more...

Award-winning impact from an ISN Mentorship pairing 

ISN Mentee Felix-Mihai Maralescu  Apply to the ISN Mentorship Program as a mentee by July 1  Felix-Mihai Maralescu, a young nephrologist from the Romanian city of Santana, was looking for research guidance when he was accepted into the ISN Mentorship Program. What he gained was a career-defining milestone!  Apply to the ISN Mentorship Program  Paired with Jochen Raimann...

May 12, 2025Grants, Mentorship, NewsRead more...

ISN Journal summaries on CKD-MBD, Pexivas trial, in-center hemodialysis, and the ISN Collaborative Quality Framework on Dialysis 

Kidney International® (KI)  Chronic Kidney Disease–Mineral and Bone Disorder: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference  The 2023 KDIGO conference confirmed that the 2017 guidelines on managing chronic kidney disease–mineral and bone disorder (CKD-MBD) remain valid but proposed reframing CKD-MBD around two clinical syndromes: CKD-associated osteoporosis and CKD-associated cardiovascular disease.  Future guidelines may...

March 24, 2025Journals, NewsRead more...

Explore the latest ISN-ACT Global Trials Focus selection featuring a “Trial of the Month” on the role of targeted exercises for children on hemodialysis  

ISN-ACT Global Trials Focus editorial team member Neeru Agarwal summarizes the design and outcomes of the latest "Trial of the Month" featured in ISN-ACT Global Trials Focus.   Trial of the Month:  Effect of muscle stretching and isometric exercises on quality of life in children undergoing regular hemodialysis  Khalf-Allah et al., Pediatric Nephrology. 2024 39:3289-3299.  Summary  In this single-center study, 68...

March 10, 2025News, ResearchRead more...

Celebrating ISN’s 2024 Publications: Driving Kidney Research for Better Patient Outcomes 

As we step into 2025, we reflect on the impactful ISN-led research of 2024. These studies deepen our understanding of kidney health and advance global kidney care as a health priority. Below, we highlight some of the year’s key contributions:    An Update on the Global Disparities in Kidney Disease Burden and Care Across World Countries...

January 6, 2025Journals, News, ResearchRead more...

A Dynamic Learning Environment: Supporting Pediatric Nephrology Training in Romania Through the ISN Educational Ambassadors Program

Participants and Educational Ambassadors Laura Castellanos-Reyes and Christine Sethna at the pediatric nephrology training course in Bucharest The ISN Educational Ambassadors Program supported comprehensive pediatric nephrology training in Romania, covering kidney disease management and the latest guidelines. The program enabled two pediatric nephrologists, Laura Castellanos-Reyes and Christine Sethna, along with a nurse, Vera Benn — all...

October 28, 2024Educational Ambassador, Grants, NewsRead more...

Latest ISN Journal Editorial Selections

Kidney International®  NAVKIDS2: A Lesson in Matching Outcomes Measures to Interventions   The Randomized Controlled Trial (NAVKIDS2) of a Patient Navigator Program Created for Children With Chronic Kidney Disease   These two studies evaluate a patient navigation program for children from disadvantaged backgrounds with chronic kidney disease (CKD), aiming to improve access to evidence-based care.   While the patient navigation...

October 14, 2024Journals, News, ResearchRead more...

Depression Management With Sertraline in Maintenance Hemodialysis Patients

ISN-ACT Global Trials Focus Subgroup member Marimar Contreras Nieves summarizes the design and outcomes of one of the latest ISN-ACT Global Trials Focus (GTF) selections. The Efficacy and Safety of Sertraline in Maintenance Hemodialysis Patients With Depression: A Randomized Controlled Study Zhang et al., J Affect Disord, 2024 May, 1:353:60-66 Summary This study evaluated the efficacy and safety of...

September 30, 2024News, ResearchRead more...

ISN Journal Editorial Selections

Kidney International® Fluid Management Protocols in Hemodialysis Patients Using Bioimpedance Validation: Time to Look Elsewhere? This study investigated the impact of clinical protocols versus bioimpedance spectroscopy (BIS) on managing volume status in hemodialysis patients and its effect on preserving residual kidney function (RKF). The findings reveal that standardized volume management protocols achieved similar outcomes to BIS in...

September 16, 2024Journals, NewsRead more...

A Simple Method to Reduce Hypotension During Hemodialysis: Ascending-Descending Ultrafiltration With Linear Sodium Profiling

ISN-ACT Global Trials Focus editorial team member Dominik Tuechler summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. The "Trial of the Month" is available in several languages, now including German. Read all global trial selections from the ISN-ACT initiative here. In addition, in the ISN 'Guide for Everyone' series, selected...

July 1, 2024News, ResearchRead more...

“I Have Made Significant Progress”: Achieve Your Goals With the ISN Mentorship Program – Apply as a Mentee by July 1

Dr. Bonilla-Felix (left) and Dr. Zamora met virtually to discuss areas for improvement Dr. Nelson Zamora Rodriguez (Bolivia) was awarded 3rd place in the ISN Mentorship Abstract Award for his submission "Prevalence of Frailty in Chronic Hemodialysis Patients at Regional Hospital San Juan De Dios, Tarija – Bolivia."   Read the full paper in the supplement...

June 18, 2024Grants, Mentorship, NewsRead more...