News

Kidney International®  

A secondary analysis of the TESTING trial predicted individual patient response to corticosteroid treatment in IgA nephropathy 

This study addressed how to better target corticosteroid treatment in IgA nephropathy, (IgAN) where benefits must be weighed against important side effects.  

Using a secondary analysis of the TESTING trial, the authors developed a model to predict each patient’s likely response to methylprednisolone. They found that treatment benefit varied widely between individuals, and that patients with higher predicted benefit had better observed outcomes.  

The findings suggest corticosteroids could be used more precisely in IgA nephropathy by focusing treatment on those most likely to benefit. 

Kidney International Reports®  

Impact of CKD on life participation in Latin America  

This study explored how chronic kidney disease (CKD) affects life participation for people in Latin America who have not yet received kidney replacement therapy. 

Using a workshop with patients, caregivers, and healthcare professionals from five countries, the researchers examined how CKD influences daily life, relationships, work, and future goals.  

The authors found that CKD often brings isolation, stigma, debilitating symptoms, and uncertainty about family and career plans, and that support from family, clinicians, spirituality, and physical activity can help build resilience.  

The findings highlight the need for strategies that help patients live better with CKD, not just manage the disease clinically.