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From Complement-Mediated Kidney Diseases to Research Skills: Use ISN Toolkits to Implement Guidelines Effectively and Translate Evidence Into Practice

Ensure you’re well-equipped in the global effort to combat kidney diseases by exploring, utilizing and sharing these valuable ISN resources.

CKD Early Identification & Intervention Toolkit

To address the burden of chronic kidney disease (CKD) and its impact on global morbidity, the ISN and KDIGO collaborated on a series of tools for CKD early identification and intervention for kidney health professionals and physicians and nurses working in primary care.

The toolkit includes:

  • A one-page quick guide
  • Early screening booklet
  • Webinars
  • Articles
  • Patient resources

The quick guide, designed to facilitate the widespread adoption of strategies to identify and treat CKD, will be available in over 50 languages by the end of 2023.

Complement-Mediated Kidney Diseases Toolkit

This toolkit presents an overview of complement-mediated

kidney diseases, which, although rarer and less well-known, are an important and complex area of kidney health that needs to be better recognized to provide optimal care.

The toolkit includes:

  • Webinars
  • Infographics

Optimization of RAASi Therapy Toolkit

Since 2021, the ISN has collaborated with the American Society for Preventative Cardiology, the Heart Failure Association of the European Society of Cardiology, the Kidney Disease Improving Global Outcomes, and the Renal Physicians Association to create toolkits to advance the prevention and management of cardio-renal complications.

The first toolkit comprises five focused and practical infographics of RAASi therapy and related complications, including:

  • Monitoring and managing hyperkalemia
  • Monitoring and managing acute changes in kidney function
  • Dietary approaches

The RAASi tools are also available in Spanish and Japanese.

Look out for the second toolkit on SGLT2i optimization in early 2024. 

ISN Research Skills Toolkit

This comprehensive toolkit, developed by the ISN in collaboration with the ISN Academy, the Young Nephrologists Committee and the ISN Clinical Research Program Committee, hosts all the ISN’s research resources in one place.

These resources help support nephrologists, especially younger generations, to contribute to advancing kidney health worldwide through research projects.

The material addresses every aspect of clinical research. It includes:

  • Guidance on designing and running clinical trials
  • Statistics and kidney biopsy courses
  • Webinars

ISN-ACT Clinical Trials Toolkit 

This toolkit is a valuable resource to support researchers and nephrologists to contribute to global research in kidney care.

This extensive guide introduces the processes involved in becoming a trial site or initiating a clinical trial. It offers clear explanations and resources to guide you through every aspect of the four stages needed to carry out clinical trials:

  • Design and development
  • Ethics and regulatory requirements
  • Conducting a trial
  • Analysis and reporting 

The CKD Early Identification & Intervention Toolkit is supported by AstraZeneca; the Complement-Mediated Kidney Diseases Toolkit is supported by Novartis; the Optimization of RAASi Therapy Toolkit is supported by AstraZeneca and CSL Vifor.


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