Tag - research

From Complement-Mediated Kidney Diseases to Research Skills: Use ISN Toolkits to Implement Guidelines Effectively and Translate Evidence Into Practice

Ensure you're well-equipped in the global effort to combat kidney diseases by exploring, utilizing and sharing these valuable ISN resources. CKD Early Identification & Intervention Toolkit To address the burden of chronic kidney disease (CKD) and its impact on global morbidity, the ISN and KDIGO collaborated on a series of tools for CKD early identification and...

November 27, 2023Initiatives, NewsRead more...

Final Modules Now Available: Complete the ISN YNC Curriculum and Gain Exclusive Access to a Webinar on Statistics for Clinical Research

Modules 5 and 6 of the CME-accredited ISN YNC Curriculum: Basics of Statistics for a Successful Start in Clinical Research are now available at the ISN Academy. Access Modules 5 and 6 now! (Join/renew your ISN membership to access this content) Module 5: Learn the applications of big data and machine learning in clinical research through...

November 27, 2023Education, News, Young nephrologistsRead more...

Efficacy of Gravity-driven Continuous Flow Peritoneal Dialysis in Children

Rupesh Raina, ISN-ACT Global Trials Focus Subgroup member, summarizes the design and outcomes of one of the team's latest trial selections. Read all the latest global trial selections from the ISN-ACT initiative here. The "Trial of the month" is available in several languages. Gravity-assisted Continuous Flow Peritoneal Dialysis Technique Use in Acute Kidney Injury in Children: A...

November 27, 2023News, ResearchRead more...

Latest ISN Journal Editorial Selections

Precision medicine framework for optimizing CKD treatment Kidney International® Trends and Perspectives for Improving Quality of Chronic Kidney Disease Care: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference  The conference discussed improving chronic kidney disease (CKD) diagnosis, care safety, and patient well-being, identifying current tools, barriers, and research needs in CKD management. Discussions acknowledged that...

November 13, 2023Journals, News, ResearchRead more...

Enhancing Scientific Writing Skills in Turkey: Testimonials From Course Participants

From left to right: Caner Alparslan, ISN Young Nephrologists Committee member (Turkey); SWC faculty members Rümeyza Kazancioğlu (Turkey), Hans Peter Marti (Norway), and Zdenka Hruskova (Czech Republic); and host and BANTAO president Mustafa Arici (Turkey)* The ISN held a Scientific Writing Course (SWC) in Istanbul from October 5-7 at Istanbul University's central campus. During the three-day...

October 30, 2023Grants, News, Scientific Writing CourseRead more...

Letermovir Non-inferior to Valganciclovir for CMV Prophylaxis, With Lower Leukopenia Rates

ISN-ACT Global Trials Focus Subgroup member Maria Chiara Pelle summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus’ latest trial selections. Read all the latest global trial selections from the ISN-ACT initiative here. The “trial of the month” is available in several languages. Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-risk Kidney Transplant...

October 30, 2023News, ResearchRead more...

ISN Journal Editorial Selections

Kidney International® A Prospective Controlled, Randomized Clinical Trial of Kidney Transplant Recipients Developed Personalized Tacrolimus Dosing Using Model-based Bayesian Prediction  In this study, a population pharmacokinetic (PPK) model, incorporating factors such as genetics, age, and hematocrit, was developed and validated to optimize tacrolimus (Tac) dosage for kidney transplant recipients. PPK-based dosing was compared with traditional weight-based dosing....

October 30, 2023Journals, News, ResearchRead more...

ISN Grants Transforming Kidney Care Globally: Meet the Latest Recipients

The ISN is delighted to announce the results of its latest grant application period. We are pleased to welcome participants from fifteen countries worldwide: Six new ISN Fellows who will receive training to help them establish or improve local care in their home regions. The awardees are from Fiji, Kenya, Nigeria, the Solomon Islands and...

October 16, 2023Clinical Research, Fellowship, Grants, Interventional Nephrology Scholarships, NewsRead more...

Balanced Crystalloid Fluids May Reduce Delayed Graft Function in Deceased Donor Kidney Transplantation – New Selection of Global Trials Out Now

To stay updated on the latest research and developments in kidney care, access the latest selection of global trials from the ISN-ACT initiative here in multiple languages. ISN-ACT Global Trials Focus Coordinator Michele Provenzano summarizes the design and outcomes of the ISN-ACT Global Trials Focus’ latest “Trial of the Month.” Balanced Crystalloid Solution Versus Saline in...

October 16, 2023News, ResearchRead more...

The 2023 ISN-GKHA: Shaping the Future of Kidney Health Worldwide – Access Region-specific Data and Use the Findings in Your Research

The 2023 ISN-Global Kidney Health Atlas (ISN-GKHA) is driving positive change in kidney care on a global scale, and you can play a role in this transformation! Assessing global kidney care: ISN-GKHA's comprehensive analysis for informed health policies The ISN-GKHA is a comprehensive resource offering an overview of the current readiness, capacity, and competence for kidney...

October 16, 2023News, ResearchRead more...

Use of Self-educational Materials Can Help Decrease Dietary Salt Intake in CKD Patients – Trial Summary and Commentary

Anastasiia Zykova, ISN Advancing Clinical Trials Network member, summarizes the design and outcomes of a study from the ISN-ACT Global Trials Focus' most recent global trials selection. Evaluation of a simple, low-cost intervention to empower people with chronic kidney disease to reduce their dietary salt intake: OxCKD1, a multi-center randomized controlled trial. Summary In this trial, 193 adult participants...

October 2, 2023News, ResearchRead more...

Explore the Reshaped ISN International Network of Chronic Kidney Disease Cohort Studies (iNET-CKD) Network Map

The newly updated ISN iNET-CKD Network cohorts map features a new layout, revised information on cohorts, and additional data. Access the ISN iNET-CKD Network cohorts map here. The ISN iNET-CKD Network is one-of-a-kind. It tracks ongoing chronic kidney disease (CKD) cohort studies located worldwide, facilitating an exchange of insights into CKD progression and its global implications. This network's...

September 18, 2023News, ResearchRead more...

Read the Latest ISN Journal Editorial Selections

Kidney International® Repurposing Drugs for Diseases Associated With Podocyte Dysfunction Due to recent advances in understanding the molecular and cellular mechanisms underlying podocyte injury, there is potential for repurposing already approved therapeutics for treating these disorders. This mini-review explores the complexities of repurposing drugs for kidney treatment, emphasizing the importance of extensive testing, emerging technologies, early intervention,...

September 18, 2023ELP, Journals, News, ResearchRead more...

Forewarned or Forearmed: Do Automated Medication-targeted Alerts Improve AKI Outcomes? Trial Summary and Commentary

Nikolay Bulanov, ISN-ACT Global Trials Focus Subgroup member, summarizes the design and outcomes of a study from the ISN-ACT Global Trials Focus' most recent global trials selection and comments on the trial's limitations. A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes Summary: In this parallel-group, pragmatic, open-label trial, 5060 hospitalized...

September 18, 2023News, ResearchRead more...

Master the Art of Data Analysis and Interpretation With a Six-part Video Curriculum: “Basics of Statistics for a Successful Start in Clinical Research”

Whether taking your first steps into clinical research or looking to improve your statistical skills, the ISN Young Nephrologists Committee's six-part video curriculum guides you to use statistics effectively and analyze and interpret data from clinical trials and studies. Access Chapter I, Modules 1 and 2 now! Module 1: Learn study design basics and the...

September 4, 2023Education, News, Young nephrologistsRead more...

Results From the iNET-CKD Study on Hemoglobin in Global CKD Populations Published in Kidney International Reports®

The "Regional Variation in Hemoglobin Distribution Among Individuals With CKD: the ISN International Network of CKD Cohorts" study, led by ISN iNET-CKD* investigators, addresses anemia's global prevalence in people living with chronic kidney disease (CKD). Read the manuscript here. Current guidelines suggest a uniform hemoglobin (Hb) range for all people with CKD, but this research examines...

September 4, 2023News, ResearchRead more...

High-dose Hemodiafiltration or Hemodialysis for Patients With Kidney Failure? Michele Provenzano on the CONVINCE Trial

Michele Provenzano summarizes the design and outcomes of the ISN-ACT Global Trials Focus’ latest “Trial of the Month” and comments on possible mechanisms of the benefit and limitations of the results. A CONVINCE-ing trial for Hemodiafiltration Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure Reviewed by Dr. Provenzano, ISN-ACT Global Trials Focus Subgroup...

September 4, 2023News, ResearchRead more...

How to Write a Winning Abstract in Ten Easy Stages

Watch the webinar “Winning Steps for a Successful WCN’24 Abstract Submission and Beyond.” It’s abstract submission season! How can you write a good abstract that will get accepted to WCN’24? WCN’24 abstract reviewers Sabine Karam, Magdalena Madero, Roberto Pecoits-Filho and Rob Walker have got you covered! Follow their foolproof advice on writing a winning abstract...

September 4, 2023Education, News, Research, WCNRead more...

Help Shape the Global Kidney Care Landscape: Download, Use and Share the ISN-Global Kidney Health Atlas Region-specific Summary Slides

The ISN-Global Kidney Health Atlas (ISN-GKHA) team has produced region-specific summary slides from the 2023 ISN-GKHA edition. Access the documents* here: Africa, Eastern and Central Europe, Latin America, Middle East, NIS and Russia, North America and the Caribbean, North and East Asia, Oceania and South East Asia, South Asia, Western Europe. Why are these slides useful? This...

August 22, 2023Featured, News, ResearchRead more...

Latest ISN Journal Summaries

Kidney International ® Editorial Selections The Power of “Negative” Experiments: Harry Goldblatt’s Pathway to Discovering How Renal Ischemia Causes Hypertension The author demonstrates that Harry Goldblatt’s willingness to conduct and publish studies with negative outcomes led to a fundamental understanding of blood pressure control within less than a decade of his initial discovery, published in...

August 22, 2023Journals, News, ResearchRead more...