ISN Journal summaries on nephrotic syndrome in children and obesity’s role in CKD
Kidney International®
The 2025 KDIGO executive summary updates guidance on managing nephrotic syndrome in children, introducing a treatment algorithm and aligning definitions with international standards.
It revises relapse prevention strategies, recommends against routine steroid use during infections, and emphasizes personalized selection of immunosuppressive agents without a fixed treatment hierarchy.
The update supports more flexible, patient-centered care based on the latest evidence.
Kidney International Reports®
New obesity guidelines and implications for CKD
Obesity’s role in chronic kidney disease (CKD) continues to be defined further, requiring clearer diagnostic and treatment guidelines.
The Lancet Commission on Obesity proposed a new disease definition and diagnostic criteria, distinguishing clinical and preclinical obesity and linking metabolically unhealthy obesity to CKD.
The updated guidelines, pending validation by relevant medical societies, offer a more comprehensive approach to obesity management in CKD.
