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ISN Journal summaries on membranous nephropathy and disaster management

Kidney International®

Designing clinical trials for the treatment of membranous nephropathy in the anti-PLA2R era: Results of a NephCure membranous nephropathy workshop

Membranous nephropathy (MN) is a leading cause of adult nephrotic syndrome, and anti-PLA2R antibodies are now recognized as key biomarkers reflecting disease activity in many patients.

At a 2023 NephCure workshop, experts discussed how to better incorporate these biomarkers into clinical trial design for MN treatments. While aPLA2R levels are already used to guide care and are included in some trials, standardization of assays and clear response thresholds are still lacking.

The workshop concluded with a call to unify existing datasets and resources to advance precision drug development in MN.

 

Kidney International Reports®

Scoping review of kidney patients and providers perspectives on disaster management

Patients with kidney disease are particularly vulnerable during disasters, underscoring the importance of understanding the experiences of those affected.

This scoping review examined existing empirical studies on how patients, caregivers, and healthcare professionals prepare for and experience such events.

The review found that relevant literature is limited and often methodologically weak. To address this, the authors propose key research priorities to guide future studies and strengthen disaster-specific kidney care.

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