ISN Journal Editorial Selections
Kidney International® A Prospective Controlled, Randomized Clinical Trial of Kidney Transplant Recipients Developed Personalized Tacrolimus Dosing Using Model-based Bayesian Prediction In this study, a population pharmacokinetic (PPK) model, incorporating factors such as genetics, age, and hematocrit, was developed and validated to optimize tacrolimus (Tac) dosage for kidney transplant recipients. PPK-based dosing was compared with traditional weight-based dosing....