Research

Provide Your Input: Complete a Survey on Fluid Management Practices in Kidney Replacement Therapy Patients

Fluid removal is a principal component of the kidney replacement therapy (KRT) prescription. However, there is a lack of high-quality evidence to guide fluid balance management in this context. The Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Canada, is conducting a survey to learn more about the attitudes and practice patterns of intensivists and nephrologists...

Listen to Season 2, Episode 1 of the ISN GKC Podcast on Early Identification and Intervention of Chronic Kidney Disease

Roberto Picoits-Filho and Smeeta Sinha talk to Michael G. Shlipak, University of California, San Francisco, and Sri Lekha Tummalapalli, Weill Cornell Medicine, about the KDIGO Controversies Conference and the resulting ISN-KDIGO Chronic Kidney Disease (CKD) Early Identification and Intervention Toolkit. Listen to the Podcast Drs. Tummalapali and Shlipak discuss current screening recommendations, testing, and treatment for...

Follow the Live #NephTrials Discussion on Spironolactone and its Impact on Dialysis Patients: Join on September 28 @ 9 p.m. EST

The #NephTrials initiative is an exciting series of conversations combining expertise from: The ISN-ACT Global Trials Focus The ISN-ACT Toolkit The #NephJC community Join us on September 28, 2021, at 9 p.m. EST to discuss: Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease (ACHIEVE), evaluating if spironolactone reduces heart failure and heart-related deaths in dialysis patients. — Discussion focus: Run-in periods: useful or threat...

Announcing a New Webinar Series on Mineralocorticoid Receptor Antagonists (MRAs) and Diabetic Kidney Disease (DKD) Management

Connect to the first webinar on September 7, 2021, from 3 - 4.15 p. m. CEST Register here. Prevention and treatment of DKD are critical to the future of global kidney health. Previously, the use of MRA in DKD has been limited by its adverse side effects. The development of non-steroidal MRAs seeks to optimize DKD treatment...

Increased Visibility for ISN’s Dialysis Framework

The ISN Framework for Developing Dialysis Programs in Low-Resource Settings is now available on the World Health Organization's NCD webpage. The framework, launched at the Global Policy Kidney Forum, ensures equal access to quality dialysis for kidney failure patients around the globe, as outlined in this article in The Lancet. The ISN encourages all to download...

2019 ISN GKHA Survey Results on Worldwide Kidney Care Capacity Published in BMJ Open

The paper, “Current status of health systems financing and oversight for end-stage kidney disease care: a cross-sectional global survey,” has been published in BMJ Open. Read the paper here. The ISN GKHA is a worldwide survey to assess the current capacity for kidney care. Designed to document the availability of the six principles* of Universal Health Coverage...

ISN i3C Network: Watch a Series of Webinars on Kidney Biopsy, Explore Ongoing CKDu Research, and Share Your Data on the ISN Observatory of CKDu

From the ISN i3C (International Consortium CKDu Collaborators) network: A series of innovative digital activities to guide nephrologists and healthcare leaders on implementing a kidney biopsy program. The activities include webinars, educational videos, and two audio interviews on the ISN Academy. Access here. The ISN Observatory of CKDu facilitates data sharing and collaboration between the diverse...

Access Chapter Two of the ISN-ACT Clinical Trials Toolkit Narratives

To facilitate understanding of important clinical trial methodologies, the ISN-ACT Clinical Trials Toolkit subgroup members are producing a series of stories based on various ISN-ACT Clinical Trials Toolkit topics. The second of these narratives outlines several trial design methods through fictional clinical discussions. Access chapter two here. The ISN-ACT Clinical Trials Toolkit is a comprehensive step-by-step...

Paper on Kidney Biopsy Codes Published

BMC Nephrology has published a paper on coding practice in national and regional kidney biopsy registries. The paper gives an overview of kidney biopsy registries, explores how kidney diseases are coded, and demonstrates the need to improve coding practice. This is the first publication from the Kidney Biopsy Codes for pathologists project, which aims to provide...

Kidney International Reports Celebrates Five Years of Presenting Outstanding Research in Nephrology

The Kidney International Reports' (KIR) Jai Radhakrishnan, editor-in-chief, Sumit Mohan, deputy editor, and Radha McLean, executive editor, highlight the journal's significant role in disseminating valuable research in nephrology, having published over 1,000 articles since its launch in 2016. The article, 5 Years (And Counting) of Expanding Access to Kidney Disease Research, marking the fifth anniversary...

International Consensus Definitions of Clinical Trial Outcomes for Kidney Failure: 2020 – Slide Deck and User Guide

In October 2020, Kidney International published the International Consensus Definitions of Clinical Trial Outcomes for Kidney Failure: 2020 developed from the 1st International Consensus Meeting on Defining Kidney Failure in Clinical Trials hosted by the ISN in Vancouver, BC, Canada, earlier that year. The paper has been summarized into a slide deck and user guide for...

ISN-H4KH Grant Awardee Has Research Results Published in KI Reports

In 2018, Amarasiri de Silva (Sri Lanka/USA) received an ISN-H4KH (Hydration for Kidney Health) Fellowship Grant. His abstract, "POS-314 People’s knowledge of Chronic Kidney Disease of Unknown Etiology in Sri Lanka," was accepted for presentation at WCN21 and published in Kidney International Reports. Amarasiri de Silva investigated a Sri Lankan population's knowledge of CKDu, and their...

Announcing the Updated ISN-ACT Clinical Trials Toolkit

An updated edition of the ISN-ACT Clinical Trials Toolkit is now available. It includes additional content and new resources. The Toolkit was updated and improved based on feedback from the ISN-ACT Toolkit subgroup and the nephrology community. The Toolkit is an ISN open-access, online resource to guide trial design, study conduct, data management, data analysis, and publications....

Final Webinar in the SGLT2i Series: Toward Equitable Access to Kidney Treatment

The ISN Webinar, Dissemination and Implementation of Therapies for Kidney Diseases in Low- and High-Income Countries, will be broadcast on Thursday, April 29, at 3 p.m. CEST (convert to your time zone here). Register here. SGLT2i inhibitors protect the heart and the kidney, but equitable access to these and other drugs for Chronic Kidney Disease and...

2019 ISN GKHA Survey Results of Country-specific Data on Kidney Care Published in KIS

The objective of the ISN Global Kidney Health Atlas (GKHA) is to provide a snapshot of individual country and regional health system characteristics, as well as specific elements relevant to the management of patients with kidney failure in terms of the WHO health systems building blocks. Our collection of manuscripts from the ten ISN regions,...

Explore Ongoing CKDu Research and Share Your Data on the ISN Observatory of CKDu

The ISN i3C (International Consortium CKDu Collaborators) group has redesigned the ISN Observatory of CKDu map. Access the map and share your data here. The map facilitates collaboration and data exchange to raise awareness of the urgent issue of chronic kidney disease of unknown etiology (CKDu). This initiative was developed as part of ISN’s 2018-2020 Collaboration Plan...

Available Now: CKD Toolkit for Healthcare Professionals

The ISN and KDIGO have partnered to create tools on CKD early identification and intervention for kidney health professionals, primary care physicians, and nurses working in primary care settings. Access the toolkit here. The ISN-KDIGO CKD Early Identification & Intervention Toolkit includes quick guides, infographics, teaching tools, as well as research articles, webcasts, and reports. The toolkit...

Narratives on ISN-ACT Clinical Trials Toolkit

To illustrate the ISN-ACT Clinical Trials Toolkit’s usability and facilitate understanding of important clinical trial methodologies, ISN-ACT Clinical Trials Toolkit subgroup members are developing a series of stories based on various toolkit topics. The first of these narratives, by Augusto Cesar Soares dos Santos and Brendan Smyth, outlines trial randomization methods through a fictional clinical...

Announcing the Winners of Early-Career Researcher Awards

The ISN-KI Early-career Researcher Award recognizes outstanding research in basic and clinical science published in Kidney International (KI) in 2019 and 2020. The winners are: Basic science Sho Hasegawa (Japan) Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury Qi Cao (Australia) Regulatory innate lymphoid cells suppress innate immunity and reduce renal ischemia/reperfusion injury Clinical science Madhav C. Menon (USA) Genome-wide...