Tag - nephrotic syndrome

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ISN Journal summaries on felzartamab for IgA nephropathy and a new anti-podocin ELISA  

Kidney International®   Randomized, double-blind, placebo-controlled phase 2a study assessing the efficacy and safety of felzartamab for IgA nephropathy  A phase 2a trial tested felzartamab, an anti-CD38 antibody, in 54 patients with IgA nephropathy. Patients received different doses of felzartamab or placebo over six months.   Felzartamab reduced protein in the urine, with the strongest and longest-lasting effect seen...

October 27, 2025Journals, News, ResearchRead more...

ISN Journal summaries on nephrotic syndrome in children and obesity’s role in CKD 

Kidney International®  Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children  The 2025 KDIGO executive summary updates guidance on managing nephrotic syndrome in children, introducing a treatment algorithm and aligning definitions with international standards.   It revises relapse prevention strategies, recommends against routine steroid use during infections, and emphasizes personalized...

May 12, 2025Journals, NewsRead more...

A Cross-Continental Collaboration to Improve Pediatric Kidney Care Through the ISN Sister Renal Centers Program

The main objective of the eight-year ISN Sister Renal Centers (SRC) partnership was to improve the quality of pediatric kidney care at the Research & Clinical Institute for Pediatrics (RCIP), Pirogov Russian National Research Medical University, in Moscow, Russia, with support from the University Hospital (UZ) Leuven and Catholic (KU) Leuven University in Leuven,...

June 3, 2024Grants, News, Sister Renal CentersRead more...

ENVISION-ing a New Way Forward in IgA Nephropathy A Phase 2 Trial of Sibeprenlimab 

Daniel O’Hara, ISN-ACT Global Trials Focus coordinator, summarizes the design and outcomes of the latest "Trial of the Month." Explore all the global trial selections for November and December here. The "Trial of the Month" is available in several languages. A Phase 2 Trial of Sibeprenlimab in Patients With IgA Nephropathy Mathur et al., N Engl J Med...

December 11, 2023News, ResearchRead more...