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Explore the ISN Global Trials Focus Selection for February and March, Featuring a “Trial of the Month” on the Efficacy and Safety of Aldosterone Synthase Inhibition 

ISN-ACT Global Trials Focus editorial team member Neeru Agarwal summarizes the design and outcomes of the latest ISN-ACT Global Trials Focus "Trial of the Month."  The "Trial of the Month" is available in several languages, now including German. Read all global trial selections from the ISN-ACT initiative here. In addition, selected clinical trials are demystified for the layperson.  Part of the...

April 23, 2024News, ResearchRead more...

Protecting IgA Nephropathy Patients: Sparsentan Reduces Proteinuria and Preserves Kidney Function Through to Two Years

ISN-ACT Global Trials Focus editorial team member Neeru Agarwal summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. Read all global trial selections from the ISN-ACT initiative here. The "trial of the month" is available in several languages. In addition, selected clinical trials are demystified for the layperson. Efficacy and safety...

March 18, 2024News, ResearchRead more...

A Ray of Light for People Living With Chronic Kidney Disease: A Promising Digital Physical Activity Intervention

ISN-ACT Global Trials Focus editorial team member Megan Borkum summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. Read all global trial selections from the ISN-ACT initiative here. The "trial of the month" is available in several languages. In addition, selected clinical trials are demystified for the layperson. Evaluating the effect...

March 4, 2024News, ResearchRead more...

Sparsentan Decreased Proteinuria, but Failed to Slow eGFR Decline in FSGS: Data From the DUPLEX Trial – New Selection of Global Trials Out Now!

ISN-ACT Global Trials Focus Subgroup member Anastasiia Zykova summarizes the design and outcomes of the team's latest "Trial of the Month." Stay updated on the latest research and developments in kidney care: Access the new selection of global trials from the ISN-ACT initiative here. The "Trial of the Month" is available in several languages. Sparsentan Versus Irbesartan...

February 19, 2024News, ResearchRead more...

Demystifying Global Kidney Trials: Providing Clear Explanations for All With a New ISN Patient-Focused Initiative

Discover the "ISN Global Kidney Trials Insights: A Guide for Everyone," a new ISN initiative for people living with kidney diseases and others interested in kidney-related clinical trials. The project intends to foster meaningful communication between patients and kidney care practitioners and increase patient participation in clinical trials. Read the first study in the guide comparing...

February 5, 2024News, ResearchRead more...

Letermovir Non-inferior to Valganciclovir for CMV Prophylaxis, With Lower Leukopenia Rates

ISN-ACT Global Trials Focus Subgroup member Maria Chiara Pelle summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus’ latest trial selections. Read all the latest global trial selections from the ISN-ACT initiative here. The “trial of the month” is available in several languages. Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-risk Kidney Transplant...

October 30, 2023News, ResearchRead more...

Use of Self-educational Materials Can Help Decrease Dietary Salt Intake in CKD Patients – Trial Summary and Commentary

Anastasiia Zykova, ISN Advancing Clinical Trials Network member, summarizes the design and outcomes of a study from the ISN-ACT Global Trials Focus' most recent global trials selection. Evaluation of a simple, low-cost intervention to empower people with chronic kidney disease to reduce their dietary salt intake: OxCKD1, a multi-center randomized controlled trial. Summary In this trial, 193 adult participants...

October 2, 2023News, ResearchRead more...

Forewarned or Forearmed: Do Automated Medication-targeted Alerts Improve AKI Outcomes? Trial Summary and Commentary

Nikolay Bulanov, ISN-ACT Global Trials Focus Subgroup member, summarizes the design and outcomes of a study from the ISN-ACT Global Trials Focus' most recent global trials selection and comments on the trial's limitations. A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes Summary: In this parallel-group, pragmatic, open-label trial, 5060 hospitalized...

September 18, 2023News, ResearchRead more...

High-dose Hemodiafiltration or Hemodialysis for Patients With Kidney Failure? Michele Provenzano on the CONVINCE Trial

Michele Provenzano summarizes the design and outcomes of the ISN-ACT Global Trials Focus’ latest “Trial of the Month” and comments on possible mechanisms of the benefit and limitations of the results. A CONVINCE-ing trial for Hemodiafiltration Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure Reviewed by Dr. Provenzano, ISN-ACT Global Trials Focus Subgroup...

September 4, 2023News, ResearchRead more...

Explore the Latest #NephTrials Discussion on Dapagliflozin and CKD on the ISN’s Twitter Feed

The latest #NephTrials online discussion took place on March 10. Access the Twitter thread here. Twitter attendees joined Ron Gansevoort, Roberto Pecoits-Filho, Joel Topf, Manasi Bapat, and Swapnil Hiremath to discuss the RENAL LIFECYCLE trial. The conversation examined the composite and secondary outcomes of a randomized control trial investigating the effects of dapagliflozin on people with severe...

March 20, 2023News, ResearchRead more...

Implement Evidence-based Care in Your Healthcare Center – Discover Kidney Research Outcomes From the ISN-ACT Global Trials Focus

The ISN-ACT Global Trials Focus (GTF) is a monthly selection of recent interesting trials relevant to kidney care. Each month, one trial is spotlighted as the "trial of the month." Recent trials of the month include: Cooled Enthusiasm for Lower Dialysate Temperatures; No Demonstrated Benefit for Cardiovascular Outcomes Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers Show Reassuring...

March 6, 2023News, ResearchRead more...

Join the ISN and Guests Live on March 10 for the Latest #NephTrials Discussion on the RENAL LIFECYCLE Trial Outcomes on Dapagliflozin and CKD

The next #NephTrials will be held on March 10, 2023, at 3 p.m. CET! Join Ron Gansevoort, primary investigator of the RENAL LIFECYCLE trial, in conversation with Michael Walsh, Roberto Pecoits-Filho, Joel Topf, Manasi Bapat, and Swapnil Hiremath. The panel will examine the composite and secondary outcomes of a randomized control trial investigating the effects...

March 6, 2023News, ResearchRead more...

Pin Your Trial Network on the ISN Network of Trials Networks Map!

The ISN-ACT (Advancing Clinical Trials) has created an online map tracking trial networks in kidney care research around the world. The aim is to facilitate clinical trial capacity and professional exchanges and collaboration by connecting people undertaking clinical trials and related studies in nephrology. The map allows researchers to quickly locate trial networks with the capacity...

January 23, 2023News, ResearchRead more...

Take Part in the ISN GTF Twitter Space to Discuss the TESTING Randomized Clinical Trial on Oral Methylprednisolone

  Join the ISN Global Trials Focus (GTF) editorial team and researchers from the TESTING* study for a live audio discussion on the GTF project and the TESTING randomized clinical trial on oral methylprednisolone. Access the Twitter Space conversation here on November 17, 2022, at 10 p.m. CET. Scan the QR code in the image above to...

November 15, 2022News, ResearchRead more...

Ten Participants Receive Expert Guidance at the Ongoing ISN Online Scientific Writing Course

The ISN Online Scientific Writing Course, cohosted by Sociedad Latinoamericana de Nefrología e Hipertensión (SLANH), is currently holding its second edition, running live sessions on each of the four Saturdays in May. The course, held in English, brings young researchers from the Latin American region closer to their goal of getting published as they receive exclusive, one-to-one tutoring...

May 23, 2022Grants, NewsRead more...

Discover Highlights from a Successful First iNET-CKD Webinar on Building a Cohort Study

Would you like to understand the key design elements of a cohort study and learn how to draft a study protocol? Watch the first iNET-CKD webinar, "Building a Cohort Study: Insight from Investigators," here. More than 200 people attended the webinar on May 10, generating a lively conversation on Twitter: Access the thread here. Participants came...

May 23, 2022News, ResearchRead more...