Results of Open-label Extension of the ORIGIN Study – Explore the Visual Abstract
This visual abstract was supported by Vera Therapeutics. Download Visual Abstract
Celebrating Excellence: Meet Eleven New ISN-Named Fellows
The ISN congratulates its newest ISN-Named Fellows: Megan Borkum and Neeru Agarwal for ISN-ACT (clinical trials) Rajitha A. Abeysekera for SharE-RR (registries) Somkanya Tungsanga, Nivedita Kamath, Victoria Nkunu, Caner Alparslan, Viviane Calice-Silva, Abduzhappar Gaipov, Anna Francis and Maria Pippias, for ISN-GKHA (ISN-Global Kidney Health Atlas) Learn more about our ISN-Named Fellows here These early-career ISN members were approved as ISN-Named...
New Perspectives on Treatment Protocols: Kidney International® Publishes Late-breaking Clinical Trials
Two significant research studies were accepted as late-breaking clinical trials at Kidney Week 2024 and have subsequently been published in Kidney International®. Higher Intraoperative Blood Pressure Does Not Reduce Acute Kidney Injury in Non-Cardiac Surgery: What Do the Results of the POISE-3 Trial Tell Us? The POISE-3 trial's analysis found no benefit in targeting a...
The ISN Holds Consensus Meeting on Changing Paradigms of Studies in CKD
The ISN PARADIGM meeting took place in Vancouver, BC, Canada, from November 22-23, 2024. The meeting gathered clinicians, trialists, patient partners, regulators, and industry scientists to rethink current concepts of laboratory values in chronic kidney disease (CKD) populations, the value of patient-reported outcomes, and trial designs while fostering a robust culture of clinical trials. The program...
Latest ISN Journal Editorial Selections
Kidney International® Patients With Crush Syndrome and Kidney Disease: Lessons Learned From the Earthquake in Kahramanmaraş, Türkiye This study assessed in-hospital outcomes and related factors in 1,024 adult patients diagnosed with post-earthquake crush syndrome following the 2023 earthquakes in Kahramanmaraş, Türkiye. A 9.8% mortality rate was reported. Nonsurvivors were older, were more likely to have preexisting chronic...
2023 ISN-GKHA Paper on Quality and Monitoring of Kidney Care Published in Nephrology
Nephrology has published the paper "Structures for Quality Assurance and Measurements for Kidney Replacement Therapies: A Multinational Study From the ISN-GKHA" by Ekrikpo et al. This study evaluates the capacity for delivering quality kidney failure care globally using data from the 2023 ISN Global Kidney Health Atlas (GKHA). The findings highlight variability in quality assurance standards,...
Latest ISN Journal Editorial Selections
Kidney International® NAVKIDS2: A Lesson in Matching Outcomes Measures to Interventions The Randomized Controlled Trial (NAVKIDS2) of a Patient Navigator Program Created for Children With Chronic Kidney Disease These two studies evaluate a patient navigation program for children from disadvantaged backgrounds with chronic kidney disease (CKD), aiming to improve access to evidence-based care. While the patient navigation...
A New Intervention for TARGETing Resistant Hypertension
Effect of Alcohol-Mediated Renal Denervation on Blood Pressure in the Presence of Antihypertensive Medications: Primary Results From the TARGET BP I Randomized Clinical Trial Kandzari et al, Circulation, 2024 Jun 11;149(24):1875-1884 ISN-ACT Global Trials Focus coordinator Megan Borkum summarizes the design and outcomes of one of the latest ISN-ACT Global Trials Focus (GTF) selections. Summary: The TARGET...
Save the Date: ISN-ANIO Workshop on Global Clinical Trials in Diverse Populations – Registration Opening Soon!
The clinical trials workshop will be held on February 5, 2025, at the Pride Plaza Aerocity in New Delhi, India, directly preceding the ISN World Congress of Nephrology 2025 (WCN’25) from February 6-9, 2025. It is organized by the ISN-ANIO committee, a collaboration between the ISN and the American Nephrologists of Indian Origin (ANIO) This...
Building Skills for Young Researchers One ISN Webinar at a Time – Register for November’s Session!
By Ahad Qayyum (Pakistan) The ISN has long considered capacity-building and education for young nephrologists a key priority. The Young Nephrologists Committee (YNC) has played a significant role in ISN initiatives that help its members improve their scientific writing skills, interpret data, and build a professional network. Recent initiatives include an ongoing webinar series to...
ISN-GKHA Data Highlights Progress and Challenges in Global Kidney Care Delivery: BMJ Publication
The BMJ has published the paper, "Progress of Nations in the Organisation of, and Structures for, Kidney Care Delivery Between 2019 and 2023: Cross-Sectional Survey in 148 Countries" by Okpechi et al. Using data from the ISN Global Kidney Health Atlas (GKHA) 2019 and 2023 reports, the study analyzed changes in the availability of kidney...
Advancing Global Kidney Research: Announcing the ISN Clinical Research Program 2024 Grantees
The ISN warmly congratulates the following researchers who received grants from the ISN Clinical Research Program to undertake vital research to advance kidney care in their communities. Michael Alao (Nigeria) "Neonatal AKI Continuum Study: A Multicenter, Longitudinal Study in Nigeria" Zulfitri Azuan Mat Daud (Malaysia) "Mobile App to Improve Nutrition Literacy Among CKD" (co-sponsored by the Asian Pacific...
Latest ISN Journal Editorial Selections
Kidney International® Repurposing Drugs for Diseases Associated With Podocyte Dysfunction Podocyte disorders often lead to chronic kidney disease and kidney failure, with current treatments relying on nonspecific immunosuppressants that have serious side effects. Recent advances in understanding the molecular mechanisms of podocyte injury offer new opportunities, including the potential to repurpose existing FDA-approved drugs for kidney-related uses. This...
ISN’s Global Kidney Health Atlas 2023 Data Highlights Kidney Care Inequalities in New Supplement Release
The Nephrology Dialysis Transplantation (NDT) Supplement "Current Status of Kidney Care Services Across Countries: A Report from the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA)" presents results from the third edition of the ISN-Global Kidney Health Atlas in a curated selection of articles relevant to public policy on kidney care. The articles highlight significant...
Investigating the Economic Burden and Cost-effectiveness Evidence Base for Rare Kidney Diseases
Rare kidney diseases (RKD) place a substantial economic burden on patients and health systems, the extent of which is unknown and may be systematically underestimated by health economic techniques. The “Scoping Review of Economic Analyses of Rare Kidney Diseases,” written in collaboration with The George Institute for Global Health, examines the existing evidence base toward...
Back to School With the ISN Academy: Elevate Your Knowledge With Our Comprehensive Courses
As the new academic year begins, the ISN Academy is excited to welcome lifelong learners to enhance their expertise and advance their careers in kidney care with the ISN's comprehensive curriculums and courses for all levels. Access all ISN Academy courses and curriculums Here's a glimpse of what's on offer: POCUS Curriculum Course overview: Training program that...
Should You Proceed With Surgery or Tablets in Peritoneal Dialysis Patients With Advanced Secondary Hyperparathyroidism?
ISN-ACT Global Trials Focus contributor Ahad Qayyum summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. The "Trial of the Month" is available in several languages, now including German. Read all global trial selections from the ISN-ACT initiative here. In addition, in the ISN 'Guide for Everyone' series, selected clinical trials...
Top 5 Reasons to Submit an Abstract to WCN’25
It's abstract submission season! Submitting an abstract to WCN'25 is an excellent way to showcase your research and advance your career. Find out more and submit your abstract here Here are the top 5 reasons to get motivated and submit your abstract today – think abstract, think NEPHRO! NEtworking: Cultivate lasting professional relationships Prominence: Showcase your research on...
A Simple Method to Reduce Hypotension During Hemodialysis: Ascending-Descending Ultrafiltration With Linear Sodium Profiling
ISN-ACT Global Trials Focus editorial team member Dominik Tuechler summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. The "Trial of the Month" is available in several languages, now including German. Read all global trial selections from the ISN-ACT initiative here. In addition, in the ISN 'Guide for Everyone' series, selected...
“I Have Made Significant Progress”: Achieve Your Goals With the ISN Mentorship Program – Apply as a Mentee by July 1
Dr. Bonilla-Felix (left) and Dr. Zamora met virtually to discuss areas for improvement Dr. Nelson Zamora Rodriguez (Bolivia) was awarded 3rd place in the ISN Mentorship Abstract Award for his submission "Prevalence of Frailty in Chronic Hemodialysis Patients at Regional Hospital San Juan De Dios, Tarija – Bolivia." Read the full paper in the supplement...