Insight

March 08, 2022

 FEATURES
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Two Days to Go! World Kidney Day Takes Place on Thursday, March 10

Help raise awareness on this momentous day in the kidney health calendar.
The ISN encourages all to download, print, and distribute from a range of campaign material available on the World Kidney Day (WKD) website. Discover 2022 logos, leaflets and flyers, school presentations, and infographics, such as this one on improving kidney health literacy.
There is still time to organize a WKD activity! Consult the activities guide for ideas to help you set up (COVID-19-safe) activities. Pin your event on the WKD activities map to increase your visibility and show the global reach of WKD activities.
The WKD Social media toolkit provides text and images to help you raise awareness on social media. Use #WorldKidneyDay on Facebook, Twitter, Instagram, and LinkedIn. Take part in the #ShowYourKidneys challenge in support of the event and retweet or share WKD posts to help make as much noise as possible on the day.
Together, let’s make the most of World Kidney Day 2022 to advance kidney health worldwide!
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Moving Account of Waiting for a Kidney Transplant Wins Your Vote at the ISN Community Film Event

On Saturday, February 26, your votes for the 2022 ISN Film Community Best Film were tallied, and the winner was announced and recognized at WCN'22.
Watch the winning entry here!
Please join us in congratulating Jeyakumar Meyyappan, India, for the film “For Some the Wait Never Ends.”
The winning film presents snapshots from the life of Mr. Saad Ahmad Khan, a 26-year-old long-term dialysis patient from India. Mr. Khan experienced cardiac arrest during a kidney transplant attempt almost ten years ago and suffers from visual impairment as a consequence. His close family members are not suitable as kidney donors.
Mr. Khan's earnest question, "How long should I wait?" prompted the filmmakers to highlight his plight in the hope of increasing awareness of organ donation.
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Announcing the Winner of the 2022 Schrier Award

Please join us in congratulating the winner of the 2022 Schrier Award, the SRC Belarus-Germany pair:
  • Emerging center:  Belarusian Medical Academy of Postgraduate Education, Minsk, Belarus (BelMAPE)
  • Supporting center: Universitatsklinikum Charité, Berlin, Germany
Through the ISN SRC Program, the centers collaborated to improve kidney pathology services at the emerging center in Belarus and throughout the country. BelMAPE now has the capacity to train another center from the region, and a preliminary agreement has been reached to continue as an SRC Trio partnership with a hospital in Georgia.

Read the ISN's statement relating to current events in the Ukraine here.

 ISN LATEST NEWS
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Events

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Thank You for Being Part of the World Congress of Nephrology 2022!

It was a great pleasure to welcome you all to WCN'22, virtually and in person at Malaysia's first international event of the year.
More than 250 speakers delivered scientific content to delegates from around the world. There's plenty to catch up on if you missed any sessions - all virtual and in-person content is currently available on-demand to WCN'22 delegates until May 31, 2022, on the congress platform.
In addition to the scientific information and educational courses,
  • Visit the outgoing leaders, awards, and ISN@Work galleries
  • Listen to the plenary lectures on green technologies, patient advocacy, lessons learnt from two pandemics, and re-defining renal disease across disciplines and continents
  • Watch the ISN Community Film Event winning entry
  • Explore industry-hosted symposia to learn the latest developments
  • Review this year’s abstracts, and much more!
We warmly thank all WCN'22 speakers and chairs for their time and expertise; so many speakers and chairs stayed up at all hours of their night to make themselves available for live Q&A.
We are grateful to delegates for their session participation, voting in the ISN Community Film Event, engaging with us on social media, and generating lively and valuable debate during topical networking sessions. Your contributions helped make WCN'22 a successful and engaging event.
The ISN warmly thanks the congress hosts, the Malaysian Society of Nephrology, and the Asian Pacific Society of Nephrology, for their enthusiastic and dedicated efforts toward delivering a seamless program and to our industry sponsors, ISN Collective-Member Societies, and countless others who worked tirelessly behind the scenes to deliver a memorable event.
Save the date! WCN'23 will be held in Beijing, China, from March 30 - April 2. We look forward to welcoming you!
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Register for the ISN Frontiers Meeting in Bergamo, Italy, at the Early Bird Rate Until March 30

Register to benefit from the early bird registration fee.
Join the ISN, the Mario Negri Institute for Pharmacological Research, and a global panel of clinical and scientific experts for three days of specialty content at the ISN Frontiers Meeting ‘Complement-related kidney diseases: classification, genetics, and treatment.'
This meeting is accredited by the European Accreditation Council for Continuing Medical Education - full details here.
The meeting will focus on the two rare and severe prototypical complement-mediated kidney diseases:
  • Atypical hemolytic uremic syndrome (aHUS)
  • C3 Glomerulopathies/Membranoproliferative Glomerulonephritis
There is an urgent need to identify key issues for the optimal management of these two challenging diseases and undertake research to resolve controversial points.

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Grants

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Get the Training and Support You Need to Improve Kidney Care in Your Community: Apply for an ISN Fellowship

The deadline to apply is May 1, 2022.
ISN Fellows can make a real impact on advancing kidney care in their home region by:
  • Providing better standards of care for their patients
  • Training other doctors and healthcare professionals in the area
  • Pioneering new programs to improve access to treatments and services, such as peritoneal dialysis, renal pathology, or transplantation
  • Starting or continuing locally-relevant research projects
  • Connecting their home center with other ISN programs and opportunities to advance kidney care
Read more here.
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Young Nephrologists in China: Apply for a Regional Scholarship

The IACN-ISN-HKSN Scholarship supports young nephrologists to train in clinical nephrology for three months in China. The grant is a joint initiative from the International Association of Chinese Nephrologists (IACN), the ISN, and the Hong Kong Society of Nephrology (HKSN).
Find out more and apply here. The deadline to apply is May 1, 2022.
Zhou Yue from Peking University Shenzhen Hospital was selected from the most recent round of applications. She will shortly begin training at Peking University First Hospital under the supervision of Dr. Ming-hui Zhao.
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Apply for an ISN Ravi Mehta AKI Fellowship

The ISN Ravi Mehta AKI Fellowship fund supports one ISN Fellow per year from a low-resource country to train in acute kidney injury (AKI) or continuous renal replacement therapy. This training enables nephrologists to significantly improve the standards of kidney care in their home countries.
Candidates should submit their application to the main ISN Fellowship program and indicate AKI as a primary focus.
Apply to the ISN Ravi Mehta AKI Fellowship here before May 1.

Would You Like to Support the ISN Ravi Mehta AKI Fellowship Program?

The ISN invites you to make a financial contribution to the Ravi Mehta AKI Fellowship Fund here.
If you are donating with a US check, please send it to the International Society of Nephrology, 340 North Ave, 3rd Floor, Cranford, NJ 07016, USA, with the reference “Ravi Mehta AKI Fellowship.”
For any additional information, please contact the ISN at fellowship@theisn.org.
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Research

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Watch the ISN Webinar on Challenges and Opportunities for Interventions in CKDu

More than 100 people attended the ISN webinar “Challenges and Opportunities for Interventions in CKDu” organized by the ISN i3C (International Consortium CKDu Collaborators) Network on February 17, 2022.
Are you interested in carrying out research that benefits these communities and generates new insight into the disease's pathophysiology? Watch the recorded webinar here.
Moderated by Shuchi Anand, the webinar focused on the need for interventions to benefit patients and communities affected by chronic kidney disease of unknown etiology (CKDu) and Mesoamerican nephropathy. Hear from:
  • Brendan Smyth, ISN-ACT (Advancing Clinical Trials) Network member, on potentially relevant interventional study designs in CKDu
  • Nishantha Nanayakkara, ISN i3C Network member, on his experience implementing a randomized controlled trial at the individual level in a low-resource setting
  • Jason Glaser, ISN i3C Network member, on the importance of interacting with industry to assess the effects of working environments on healthcare professionals and implement positive changes
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ISN-ACT Global Trials Focus: January-February 2022

Highlight:
A summary of the highlighted trial is now available in French, Mandarin, Russian, and Spanish. See the latest trials here.
Support equal access to nephrology research, become an ISN Member!
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Advocacy

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Join us for the WKD Webinar on Thursday

To mark World Kidney Day (WKD), the joint steering committee will host two sessions of an official webinar highlighting different aspects of the 2022 theme, “Kidney Health for All - Bridge the Gap to Better Kidney Care.”
The panel, which includes participation from ISN President Agnes Fogo and the International Federation of Kidney Foundations President SF Lui, will explore ways to improve health literacy by collaborating with patients at all levels of healthcare.
Read more here.
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Connect With Experts on March 17 for a Webinar on Migrant and Refugee Transplant Issues

The Declaration of Istanbul Custodian Group (DICG) will present specific issues arising from current global crises generating fertile ground for illicit organ removal and posing challenges to the interpretation of the Declaration of Istanbul (DOI).
These include an increase in refugees and migrants due to conflicts and humanitarian crises and a decrease in available organs due to COVID-19.
“Transplantation in the Context of Migrants & Refugees: Challenges & Dilemmas” will take place at 7 a.m EST (convert to your time zone here) on Thursday, March 17, 2022.
Read more here.
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Building Healthier Sustainable Communities to Safeguard Kidney Health: the Global Kidney Policy Forum at WCN'22

The Professor Donal O'Donoghue, Global Kidney Policy Forum: Building Healthier Sustainable Communities to Safeguard Kidney Health, brought together virtually key decision-makers and stakeholders, including WHO representatives, local politicians, patients, and internationally renowned nephrologists at the World Congress of Nephrology 2022.
In line with the 12 Recommendations to Global Kidney Health guidelines, speakers addressed the burden of kidney diseases in the Southeast Asia region, discussing policies and strategies to improve kidney care and prevention at regional and global levels.
The ISN will be working with local partners to turn the forum’s recommendations into reality and help address the significant variations in the accessibility, affordability, and quality of care throughout the region.
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Patient Liaison Advisory Group Pledges to Shape Patient Perspectives Within ISN Initiatives at WCN’22 Launch

The Patient Liaison Advisory Group, comprising a patient representative from each of the ten ISN regions, will support ISN’s efforts to shape patient-centered health initiatives and research programs to address the burden of kidney disease worldwide.
The group was officially launched at the World Congress of Nephrology 2022. Following opening remarks from the ISN President, Professor Agnes Fogo, the Chair of the Patient Liaison Advisory Group, Mr. Manvir Victor, presented the group’s mission statement:
‘Created in 2021, the ISN’s Patient Liaison Advisory Group represents the inter-continental diversity of kidney patients with one representative from each of the society’s ten regions. Its mission is to advise and guide the ISN so that the patient perspective becomes embedded within our work, shaping health initiatives and research programs so that they tackle the global burden of kidney disease.’
Each group member was introduced at the launch and discussed the initiative with delegates during the Q&A session.
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Advocacy and Policy Course Equips Participants to Campaign for Better Kidney Health

The ISN's first “Advocacy and Policy Course - New Skills for the Modern Nephrologist” was held on February 24 at the World Congress of Nephrology 2022.
Internationally renowned kidney health advocates introduced the concept of advocacy and provided real-life success stories from kidney care campaigns in different countries. The course emphasized the importance of aligning advocacy strategies with patient perspectives and the need to skillfully present data to policymakers.
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EDUCATION

Podcast

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Listen to the World Kidney Day Special Edition of the ISN Global Kidney Care Podcast

The Global Kidney Care Podcast (GKCP) has recorded a special WKD episode, “World Kidney Day: Health Literacy, a Call for All Nephrologists.”
Listen to the special WKD edition of the GKCP here.
In this episode, Roberto Pecoits-Filho and Smeeta Sinha discuss the history of WKD and the 2022 campaign theme and goals with members of the WKD Steering Committee, Robyn Langham, Australia, co-chair for ISN, and SF Lui, Hong Kong, IFKF-WKA, project director.

Upcoming Webinars

Thursday, March 10

World Kidney Day 2022:
Bridge the Knowledge Gap to Better Kidney Care - Bringing Together the Community for Kidney Health

Session 1: 11 a.m. CET / Session 2: 10 p.m. CET
Speakers: Agnes Fogo, USA
SF Lui, Hong Kong
Verónica Martínez, Mexico
Manvir Victor, Malaysia
Ann Bonner, Australia
Beatrice Titilola Segun-Agboola, Nigeria
Paul Laffin, France
Moderators: Vassilios Liakopoulos, Greece (Session 1)
Kam Kalantar Zadeh, USA (Session 2)
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Monday, March 14, 4 p.m. CET

ISN-KDIGO-WONCA
Joint Webinar on the CKD Early Identification and Intervention Toolkit

Speakers: Vivekanand Jha, India
Ana Cebrian, Spain
Domingo Orozco-Beltran, Spain
Moderator: Magdalena Madero, Mexico
This webinar is supported by an unrestricted educational grant from AstraZeneca.
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Thursday, March 17, 12 p.m. CET

DICG Webinar:
Transplantation in the Context of Migrants & Refugees - Challenges & Dilemmas

Speakers: Krisof Van Assche, Belgium
Sylwia Gawronska, Thailand
Liliana Sorrentino, Switzerland
Chair: Sanjay Nagral, India
Eric Rondeau, France
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Recorded Webinar

ISN i3C Webinar:
Challenges and Opportunities for Interventions in CKDu

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COVID-19

KI-Covid

Kidney International on COVID-19

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Journals

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Watch the Latest ISN Video Abstract on Urine Single-Cell RNA-Sequencing

Watch the latest video abstract here.
This episode presents the Kidney International Reports paper:
Urine Single Cell RNA-Sequencing From Focal Segmental Glomerulosclerosis Reveal Inflammatory Signatures
Discover more video abstracts on the ISN Academy.
he ISN Video Abstract Series is an initiative by the @ISNeducation Social Media Team showcasing key articles from ISN Journals on social media platforms.
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Kidney International Editorial Selections

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Kidney Health for All: Bridging the gap in Kidney Health Education and Literacy

This special editorial, produced by the World Kidney Day (WKD) Steering Committee, aims to increase kidney disease awareness as part of the WKD 2022 campaign.
The authors encourage kidney organizations to work to shift responsibility for patient health literacy away from patients and toward health care providers and policymakers.
They recommend establishing co-designed partnerships between these groups to facilitate communication and education and reduce the deficit in patient health literacy.
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Findings From 4C-T Study Demonstrate an Increased Cardiovascular Burden in Girls with End Stage Kidney Disease and Kidney Transplantation

Mortality in children with kidney failure is higher in girls than boys with cardiovascular complications representing the most common cause of death.
In this study, pulse wave velocity (PWV) was investigated in children with kidney failure undergoing kidney replacement therapy to determine sex differences and potential contributing factors.
Findings demonstrate that girls with advanced chronic kidney disease are more susceptible to developing vascular stiffening compared to boys. This difference persists after transplantation and may contribute to higher mortality rates in girls with kidney failure.
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Kidney International Reports Editorial Selections

KIR-Editorial
In the current issue of Kidney International Reports, two studies explore the role of sickle cell trait with APOL1 nephropathy:
Sickle Cell Trait and Kidney Disease in People of African Ancestry with HIV
APOL1 Renal Risk Variants and Sickle Cell Trait Associations with Reduced Kidney Function in a Large Congolese Population-Based Study
In the paper by Hung et al., which included 2,895 individuals who participated in the GEN-AFRICA study, sickle cell trait and APOL1 HR genotypes were associated with estimated glomerular filtration rates of <60 ml/min per 1.73 m2.
Masimango et al. conducted the second study of 587 adults living in the Democratic Republic of Congo. The frequency of sickle cell trait and GSTM1 null allele in individuals with and without two APOL1 risk alleles were found to be 3.8% and 51.2%, respectively.
A commentary discusses the complexity and relevance of these findings.
KI-Editorial

Ethiopia's Tigray Dialysis Service Cut Due to Dwindling Supplies Amid War

Since Ethiopia’s civil war broke out in November 2020, 70% of healthcare facilities in the Tigray region have become dysfunctional. At Ayder, Tigray’s flagship tertiary center, even basic care has become a luxury.
Ayder’s hemodialysis service, serving 9,000,000 people, was an outstanding example of sophisticated care in a low-resource environment enabled by private-public partnerships, community engagement, and an ethical commitment to care. War and blockade have caused reduced access, funding, severe supply shortages, and drastically curtailed dialysis.